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Cited by 1,167

The DOI matches its Crossref record; 33 of the 33 references it cites were found in a registry or an index.

Clinical applications of resting state functional connectivity

Open access
Fox, Michael D.·2010·Frontiers in Systems Neuroscience

Abstract

During resting conditions the brain remains functionally and metabolically active. One manifestation of this activity that has become an important research tool is spontaneous fluctuations in the blood oxygen level-dependent (BOLD) signal of functional magnetic resonance imaging (fMRI). The identification of correlation patterns in these spontaneous fluctuations has been termed resting state functional connectivity (fcMRI) and has the potential to greatly increase the translation of fMRI into clinical care. In this article we review the advantages of the resting state signal for clinical applications including detailed discussion of signal to noise considerations. We include guidelines for performing resting state research on clinical populations, outline the different areas for clinical application, and identify important barriers to be addressed to facilitate the translation of resting state fcMRI into the clinical realm.

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Metadata

Authors
Fox, M. D.
Venue
Frontiers in Systems Neuroscience
Published
2010
Volume
4
Pages
19-19
ISSN
1662-5137 (ISSN-L)
OpenAlex
W2143661428
Cited by
1,167
References
33
FWCI
35.84
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: Clinical applications of resting state functional connectivity. https://app.cochat.ai/papers/10.3389/fnsys.2010.00019
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Fox, M. D. (2010). Clinical applications of resting state functional connectivity. Frontiers in Systems Neuroscience. https://doi.org/10.3389/fnsys.2010.00019

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.