Breast Cancer Survivorship, Quality of Life, and Late Toxicities
Open accessAbstract
Breast cancer is the most frequent cancer in women: in 2018, almost two million cases have been diagnosed all over the world and it represents the principal cause of death from a neoplastic disease in women. In the past years, breast cancer prognosis has significantly improved over time: currently 5-year survival rates are in the range of 90%, and 10-year survival is about 80%. This improvement has been mostly observed in western countries, due to high coverage and compliance with screening programs, leading to early diagnosis, i.e., when the disease is at a subclinical level, and to an improvement in tumor molecular characterization and innovative systemic treatments. Yet the identification of different biological breast cancer subtypes prompted the development of innovative targeted agents and improved treatment personalization. On the other hand, longer survival rates and increasing proportions of cured patients require dedicated strategies to manage long-term sequelae of breast cancer treatments, with particular attention to quality of life. This review analyzes the most important issues, potentially occurring with cancer treatments, concerning long-term sequelae and quality of life, to define a global approach to breast cancer survivorship.
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Somatic side effects of therapy (e.g., neurotoxicity, cardiotoxicity, lymphoedema, pain) and increased tumour-related stress or mental illnesses (e.g., anxiety, depression) play a central role in follow-up care.
“In addition to somatic side effects of the therapy, such as neurotoxicity and cardiotoxicity, lymphoedema or pain [6–8], increased tumour-related stress or mental illnesses such as anxiety and depression play a central role in follow-up care.”
From The BrEasT cancer afTER-CARE (BETTER-CARE) programme to improve breast cancer follow-up: design and feasibility study results of a cluster-randomised complex intervention trial (2024) · cites this paper as [7]
The Background and Conclusions (pages not provided) say that treatment sequelae require attention and resources in breast-cancer follow-up. The Cardiotoxicity After Adjuvant Therapy section identifies cardiotoxicity as an important late effect and recommends follow-up examinations. Our copy does not identify neurotoxicity, lymphoedema or pain as examples; the citation in the printed sentence is attached to the somatic-effects clause, not the subsequent anxiety-and-depression clause. (LLM, conf=0.83)
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Cites
Bray, F., Ferlay, J., Soerjomataram, I., Siegel, R. L., Torre, L. A., & Jemal, A. (2018) · CA: A Cancer Journal for Clinicians · doi:10.3322/caac.21492 · Cited by 84,109 · see citing works
Zamorano, J. L., Lancellotti, P., Muñoz, D. R., Aboyans, V., Asteggiano, R., Galderisi, M., Habib, G., Lenihan, D. J., Lip, G. Y. H., Lyon, A. R., et al. (2016) · European Heart Journal · doi:10.1093/eurheartj/ehw211 · Cited by 2,598 · see citing works
Effect of Screening and Adjuvant Therapy on Mortality from Breast Cancer
Berry, D. A., Cronin, K. A., Plevritis, S. K., Fryback, D. G., Clarke, L. D., Zelen, M., Mandelblatt, J. S., Yakovlev, A. Y., Habbema, J. D. F., & Feuer, E. J. (2005) · New England Journal of Medicine · doi:10.1056/nejmoa050518 · Cited by 2,456 · see citing works
Pertuzumab, Trastuzumab, and Docetaxel in HER2-Positive Metastatic Breast Cancer
Swain, S. M., Baselga, J., Kim, S.-B., Ro, J., Semiglazov, V., Campone, M., Ciruelos, E., Ferrero, J.-M., Schneeweiss, A., Heeson, S., et al. (2015) · New England Journal of Medicine · doi:10.1056/nejmoa1413513 · Cited by 2,164 · see citing works
Baum, M., Budzar, A. U., Cuzick, J. M., Forbes, J., Houghton, J., Klijn, J. G. M., & Sahmoud, T. (2002) · The Lancet · doi:10.1016/s0140-6736(02)09088-8 · Cited by 1,958 · see citing works
Zamorano, J. L., Lancellotti, P., Muñoz, D. R., Aboyans, V., Asteggiano, R., Galderisi, M., Habib, G., Lenihan, D. J., Lip, G. Y. H., Lyon, A. R., et al. (2016) · European Journal of Heart Failure · doi:10.1002/ejhf.654 · Cited by 1,800 · see citing works
Sledge, G. W., Toi, M., Neven, P., Sohn, J., Inoue, K., Pivot, X., Burdaeva, O., Okera, M., Masuda, N., Kaufman, P. A., et al. (2017) · Journal of Clinical Oncology · doi:10.1200/jco.2017.73.7585 · Cited by 1,680 · see citing works
Overall survival with ribociclib plus endocrine therapy in breast cancer
Im, S.-A., Lu, Y.-S., Bardia, A., Harbeck, N., Colleoni, M., Franke, F., Chow, L., Sohn, J., Lee, K.-S., Campos-Gomez, S., et al. (2019) · New England Journal of Medicine · doi:10.1056/nejmoa1903765 · Cited by 1,001 · see citing works
Piccart, M., Hortobagyi, G. N., Campone, M., Pritchard, K. I., Lebrun, F., Ito, Y., Noguchi, S., Perez, A., Rugo, H. S., Deleu, I., et al. (2014) · Annals of Oncology · doi:10.1093/annonc/mdu456 · Cited by 574 · see citing works
Coleman, R. E., Banks, L. M., Girgis, S. I., Kilburn, L., Vrdoljak, E., Fox, J. N., Cawthorn, S., Patel, A., Snowdon, C. F., Hall, E., et al. (2007) · The Lancet Oncology · doi:10.1016/s1470-2045(07)70003-7 · Cited by 426 · see citing works
Cardiotoxicity of anticancer treatments
Ewer, M. S., & Ewer, S. M. (2015) · Nature Reviews Cardiology · doi:10.1038/nrcardio.2015.65 · Cited by 416 · see citing works
Lambertini, M., Moore, H. C. F., Leonard, R. C., Loibl, S., Münster, P. N., Bruzzone, M., Boni, L., Unger, J. M., Anderson, R. A., Mehta, K. M., et al. (2018) · Journal of Clinical Oncology · doi:10.1200/jco.2018.78.0858 · Cited by 393 · see citing works
Saadatmand, S., Bretveld, R. W., Siesling, S., & Tilanus‐Linthorst, M. M. A. (2015) · BMJ · doi:10.1136/bmj.h4901 · Cited by 349 · see citing works
Erratum: Cardiotoxicity of anticancer treatments
Ewer, M. S., & Ewer, S. M. (2015) · Nature Reviews Cardiology · doi:10.1038/nrcardio.2015.133 · Cited by 340 · see citing works
Measures of Outcome in Metastatic Breast Cancer: Insights From a Real-World Scenario
Bonotto, M., Gerratana, L., Poletto, E., Driol, P., Giangreco, M., Russo, S., Minisini, A. M., Andreetta, C., Mansutti, M., Pisa, F. E., et al. (2014) · The Oncologist · doi:10.1634/theoncologist.2014-0002 · Cited by 295 · see citing works
Past, Present, and Future Challenges in Breast Cancer Treatment
Sledge, G. W., Mamounas, E. P., Hortobágyi, G. N., Burstein, H. J., Goodwin, P. J., & Wolff, A. C. (2014) · Journal of Clinical Oncology · doi:10.1200/jco.2014.55.4139 · Cited by 278 · see citing works
(2013) · Fertility and Sterility · doi:10.1016/j.fertnstert.2013.08.012 · Cited by 269 · see citing works
Guénancia, C., Lefebvre, A., Cardinale, D. M., Yu, A. F., Ladoire, S., Ghiringhelli, F., Zeller, M., Rochette, L., Cottin, Y., & Vergely, C. (2016) · Journal of Clinical Oncology · doi:10.1200/jco.2016.67.4846 · Cited by 213 · see citing works
Recommendations for fertility preservation in patients with lymphoma, leukemia, and breast cancer
Kim, S. S., Donnez, J., Barri, P. N., Pellicer, A., Patrizio, P., Rosenwaks, Z., Nagy, P., Falcone, T., Andersen, C. B., Hovatta, O., et al. (2012) · Journal of Assisted Reproduction and Genetics · doi:10.1007/s10815-012-9786-y · Cited by 195 · see citing works
Assessment of the risk of post‐menopausal osteoporosis using clinical factors
Ribot, C. A., Pouillès, J. M., Bonneu, M., & Trémollières, F. (1992) · Clinical Endocrinology · doi:10.1111/j.1365-2265.1992.tb01436.x · Cited by 135 · see citing works
Ovarian cryopreservation for fertility preservation: indications and outcomes
Anderson, R. A., Wallace, W. H., & Baird, D. T. (2008) · Reproduction · doi:10.1530/rep-08-0097 · Cited by 129 · see citing works
Campbell‐Enns, H. J., & Woodgate, R. L. (2015) · The JBI Database of Systematic Reviews and Implementation Reports · doi:10.11124/jbisrir-2015-1795 · Cited by 115 · see citing works
Imayama, I., Alfano, C. M., Neuhouser, M. L., George, S. M., Smith, A. W., Baumgartner, R., Baumgartner, K. B., Bernstein, L., Wang, C.-Y., Duggan, C. R., et al. (2013) · Breast Cancer Research and Treatment · doi:10.1007/s10549-013-2594-y · Cited by 88 · see citing works
Effectiveness of service screening: a case–control study to assess breast cancer mortality reduction
the IMPACT Working Group, Puliti, D., Miccinesi, G., Collina, N., Lisi, V. D., Federico, M., Ferretti, S., Finarelli, A. C., Foca, F., Mangone, L., et al. (2008) · British Journal of Cancer · doi:10.1038/sj.bjc.6604532 · Cited by 85 · see citing works
Breast cancer treatment-induced cardiotoxicity
Martel, S., Maurer, C., Lambertini, M., Ponde, N. F., & de Azambuja, E. (2017) · Expert Opinion on Drug Safety · doi:10.1080/14740338.2017.1351541 · Cited by 78 · see citing works
Intimacy and sexuality in women with breast cancer: professional guidance needed
den Ouden, M. E. M., Pelgrum-Keurhorst, M. N., Uitdehaag, M. J., & de Vocht, H. M. (2018) · Breast Cancer · doi:10.1007/s12282-018-0927-8 · Cited by 58 · see citing works
Sexual health in long-term breast cancer survivors
Soldera, S. V., Ennis, M., Lohmann, A. E., & Goodwin, P. J. (2018) · Breast Cancer Research and Treatment · doi:10.1007/s10549-018-4894-8 · Cited by 56 · see citing works
Osteoporosis management in patients with breast cancer: EMAS position statement
Trémollières, F., Ceauşu, I., Depypere, H. T., Lambrinoudaki, I. V., Mueck, A. O., Pérez-López, F. R., van der Schouw, Y. T., Senturk, L. M., Simoncini, T., Stevenson, J. C., et al. (2016) · Maturitas · doi:10.1016/j.maturitas.2016.10.007 · Cited by 50 · see citing works
Obese Breast Cancer Patients and Survivors: Management Considerations.
Sheng, J. Y.-S., Sharma, D., Jerome, G. J., & Santa-Maria, C. A. (2018) · PubMed · Cited by 42 · see citing works
Richard, A., Harbeck, N., Wuerstlein, R., & Wilhelm, F. (2018) · Psycho-Oncology · doi:10.1002/pon.4957 · Cited by 41 · see citing works
Medical approaches to preservation of fertility in female cancer patients
Mastro, L. D., Giraudi, S., Levaggi, A., & Pronzato, P. (2011) · Expert Opinion on Pharmacotherapy · doi:10.1517/14656566.2011.522568 · Cited by 39 · see citing works
Rojas, K. E., Matthews, N., Raker, C., Clark, M. A., Onstad, M., Stuckey, A., & Gass, J. (2018) · Journal of Cancer Survivorship · doi:10.1007/s11764-017-0651-y · Cited by 36 · see citing works
Fertility, sexuality and cancer in young adult women
Condorelli, M., Lambertini, M., Mastro, L. D., Boccardo, F., Demeestere, I., & Bober, S. L. (2019) · Current Opinion in Oncology · doi:10.1097/cco.0000000000000540 · Cited by 29 · see citing works
Multiple Approaches for Individualized Fertility Protective Therapy in Cancer Patients
Demeestere, I., Moffa, F., Peccatori, F. A., Poirot, C., & Shalom‐Paz, E. (2011) · Obstetrics and Gynecology International · doi:10.1155/2012/961232 · Cited by 23 · see citing works
Salakari, M., Nurminen, R., Sillanmäki, L. H., Pylkkänen, L. H., & Suominen, S. (2019) · Supportive Care in Cancer · doi:10.1007/s00520-019-05228-8 · Cited by 17 · see citing works
Manuale pratico di psico-oncologia
Grassi, L. G., Biondi, M., & Costantni, A. (2003) · Institutional Research Information System University of Ferrara (University of Ferrara) · Cited by 14 · see citing works
Eagle, I. T., Benavides, E., Eber, R., Kolenic, G. E., Jung, Y., Poznak, C. H. V., & Taichman, L. S. (2016) · Journal Of Clinical Periodontology · doi:10.1111/jcpe.12562 · Cited by 13 · see citing works
Metastatic breast cancers: Estimates for Italy
Crocetti, E., Gori, S., & Falcini, F. (2018) · Tumori Journal · doi:10.1177/0300891618766177 · Cited by 9 · see citing works
Aseyev, O., Johnson, C. B., Turek, M. A., Stadnick, E., Law, A., Gosh, N., & Dent, S. F. (2017) · Cancer Research · doi:10.1158/1538-7445.sabcs16-p2-07-06 · Cited by 2 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Breast Cancer—Epidemiology, Classification, Pathogenesis and Treatment (Review of Literature)
Smolarz, B., Nowak, A. Z., & Romanowicz, H. (2022) · Cancers · doi:10.3390/cancers14102569 · Cited by 642 · see citing works
Whittaker, A. L., George, R. P., & O'Malley, L. A. (2022) · Scientific Reports · doi:10.1038/s41598-022-05682-1 · Cited by 209 · see citing works
Fusco, N., Malapelle, U., Fassan, M., Marchiò, C., Buglioni, S., Zupo, S., Criscitiello, C., Vigneri, P. G., Tos, A. P. D., Maiorano, E., et al. (2021) · Frontiers in Oncology · doi:10.3389/fonc.2021.644737 · Cited by 121 · see citing works
Morales-Sánchez, L., Luque-Ribelles, V., Márquez, P. G.-O., Ruíz-González, P., & Bozal, R. G. (2021) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph18041640 · Cited by 108 · see citing works
Unmet supportive care needs of breast cancer survivors: a systematic scoping review
Fan, R., Wang, L., Bu, X., Wang, W., & Zhu, J. (2023) · BMC Cancer · doi:10.1186/s12885-023-11087-8 · Cited by 103 · see citing works
Breast Cancer with Bone Metastasis: Molecular Insights and Clinical Management
Venetis, K., Piciotti, R., Sajjadi, E., Invernizzi, M., Morganti, S., Criscitiello, C., & Fusco, N. (2021) · Cells · doi:10.3390/cells10061377 · Cited by 101 · see citing works
Al-Khedhairy, A. A., & Wahab, R. (2022) · Metals · doi:10.3390/met12010148 · Cited by 86 · see citing works
Psychosocial experiences of breast cancer survivors: a meta-review
King, R., Stafford, L., Butow, P. N., Giunta, S., & Laidsaar‐Powell, R. (2023) · Journal of Cancer Survivorship · doi:10.1007/s11764-023-01336-x · Cited by 87 · see citing works
Impact of Rehabilitation on Breast Cancer Related Fatigue: A Pilot Study
Invernizzi, M., Alessandro de, S. I. R. E., Lippi, L., Venetis, K., Sajjadi, E., Gimigliano, F., Gennari, A., Criscitiello, C., Cisari, C., & Fusco, N. (2020) · Frontiers in Oncology · doi:10.3389/fonc.2020.556718 · Cited by 79 · see citing works
Self-citationCDKN1A/p21 in Breast Cancer: Part of the Problem, or Part of the Solution?
Manousakis, E., Miralles, C. M., Esquerda, M. G., & Wright, R. H. G. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms242417488 · Cited by 71 · see citing works
Long-Term Effects of Breast Cancer Therapy and Care: Calm after the Storm?
Tommasi, C., Balsano, R., Corianò, M., Pellegrino, B., Saba, G., Bardanzellu, F., Denaro, N., Ramundo, M., Toma, I., Fusaro, A., et al. (2022) · Journal of Clinical Medicine · doi:10.3390/jcm11237239 · Cited by 76 · see citing works
Shiraishi, M., Sowa, Y., Tsuge, I., 児玉, 卓., Inafuku, N., & Morimoto, N. (2022) · Frontiers in Oncology · doi:10.3389/fonc.2022.815498 · Cited by 62 · see citing works
Breast Radiotherapy-Related Cardiotoxicity. When, How, Why. Risk Prevention and Control Strategies
Díaz-Gavela, A. A., Figueiras-Graillet, L. M., Luis, Á., Segura, J. S., Ciérvide, R., Peñalver, E. D. C., Couñago, F., Arenas, M., & López‐Fernández, T. (2021) · Cancers · doi:10.3390/cancers13071712 · Cited by 67 · see citing works
Chen, L., Shen, J., Kang, Z., Zhang, Z., Zheng, Z., Zhang, L., Xiao, Z., Zhang, Q., Fang, H., Zhou, J., et al. (2024) · Chem · doi:10.1016/j.chempr.2024.01.030 · Cited by 56 · see citing works
Chakravarthy, S. R. S., Bharanidharan, N., Kumar, V. V., Mahesh, T. R., Sivakami, R., & Annand, J. R. (2024) · International Journal of Computational Intelligence Systems · doi:10.1007/s44196-024-00409-8 · Cited by 50 · see citing works
Recent Advances in Diagnostic and Therapeutic Approaches for Breast Cancer: A Comprehensive Review
Noor, F., Noor, A., Ishaq, A. R., Farzeen, I., Saleem, M. H., Ghaffar, K., Aslam, M. F., Aslam, S., & Chen, J. (2021) · Current Pharmaceutical Design · doi:10.2174/1381612827666210303141416 · Cited by 47 · see citing works
Lin, Y., Wu, C., He, C., Yan, J., Chen, Y., Gao, L., Liu, R., & Cao, B. (2022) · Supportive Care in Cancer · doi:10.1007/s00520-022-07494-5 · Cited by 47 · see citing works
Zhou, K., Ning, F., Wang, W., & Li, X. (2022) · BMC Cancer · doi:10.1186/s12885-022-09177-0 · Cited by 43 · see citing works
Singh, D. P., Banerjee, T., Kour, P., Malik, R., Naidu, G. R., Durai, C. A. D., Kumar, R. S., Kaushal, R. K., Singh, R., & Narayan, Y. (2025) · Archives of Computational Methods in Engineering · doi:10.1007/s11831-025-10414-5 · Cited by 42 · see citing works
Function and Application of Flavonoids in the Breast Cancer
Park, M. Y., Kim, Y., Ha, S. E., Kim, H. H., Bhosale, P. B., Abusaliya, A., Jeong, S. H., & Kim, G. S. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23147732 · Cited by 41 · see citing works
Natalucci, V., Marini, C. F., Flori, M., Pietropaolo, F., Lucertini, F., Annibalini, G., Vallorani, L., Sisti, D., Saltarelli, R., Villarini, A., et al. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm10122678 · Cited by 42 · see citing works
Factors influencing the burden on spousal caregivers of breast cancer survivors
Lin, T., Hu, X., Chen, H., Xiao, S., & Zhang, X. (2022) · Supportive Care in Cancer · doi:10.1007/s00520-022-07130-2 · Cited by 46 · see citing works
The State of Cancer Care in the United Arab Emirates in 2022
Al-Shamsi, H. O. (2022) · Clinics and Practice · doi:10.3390/clinpract12060101 · Cited by 37 · see citing works
Schäffler, H., Mergel, F., Pfister, K., Lukac, S., Fink, A., Veselinovic, K., Rack, B. K., Fink, V., Leinert, E., Dimpfl, M., et al. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms242216366 · Cited by 36 · see citing works
Invernizzi, M., Lippi, L., Folli, A., Turco, A., Zattoni, L., Maconi, A., Alessandro de, S. I. R. E., & Fusco, N. (2022) · Frontiers in Molecular Biosciences · doi:10.3389/fmolb.2022.930361 · Cited by 36 · see citing works
Lin, T., Lv, J., Zhong, T., Zeng, X., Han, M., Fu, L., & Chen, H. (2024) · Scientific Reports · doi:10.1038/s41598-024-59214-0 · Cited by 34 · see citing works
Lin, T., Xiang, Y., Zeng, X., Fu, L., Li, J., & Chen, H. (2024) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2024.1309702 · Cited by 35 · see citing works
Emerging roles of TRIM27 in cancer and other human diseases
Yu, C., Rao, D., Wang, T., Song, J., Zhang, L., & Huang, W. (2022) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2022.1004429 · Cited by 32 · see citing works
Intratumoral implantable drug delivery system for targeted localized chemotherapy in breast cancer
Souri, M., Elahi, S., & Soltani, M. (2024) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2024.105519 · Cited by 31 · see citing works
Davey, M. G., Casey, M. C., McGuire, A., Waldron, R. M., Paganga, M., Holian, E., Newell, J., Heneghan, H., McDermott, A. M., Keane, M., et al. (2022) · Annals of Surgery · doi:10.1097/sla.0000000000005613 · Cited by 30 · see citing works
Breast Cancer in the United Arab Emirates
Al-Shamsi, H. O., Abdelwahed, N., Al-Awadhi, A. M., Mohamed, A., Abyad, A. M., Rafii, S., Afrit, M., Lababidi, B., Abu-Gheida, I. H., Sonawane, Y., et al. (2023) · JCO Global Oncology · doi:10.1200/go.22.00247 · Cited by 33 · see citing works
Gurgel, A. R. B., Mingroni-Netto, P., Farah, J. C., de Brito, C. M. M., Levin, A. S., & Brum, P. C. (2021) · Frontiers in Physiology · doi:10.3389/fphys.2021.624169 · Cited by 28 · see citing works
Yang, W., Wu, X., & Zhou, F. (2020) · Medical Science Monitor · doi:10.12659/msm.928919 · Cited by 29 · see citing works
Ke, L., Li, S., & Cui, H. (2022) · BMC Cancer · doi:10.1186/s12885-022-10284-1 · Cited by 29 · see citing works
Álvarez-Pardo, S., Romero-Pérez, E. M., Camberos, N. A., Fernández, J. A. D. P., Horta-Gim, M. A., Gonzalez-Bernal, J. J., Mielgo‐Ayuso, J., Simón‐Vicente, L., Fernández-Solana, J., & González‐Santos, J. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph192316229 · Cited by 28 · see citing works
Effect of tumor-associated macrophages on the pyroptosis of breast cancer tumor cells
Ji, X., Huang, X., Li, C., Guan, N., Pan, T., Dong, J., & Li, L. (2023) · Cell Communication and Signaling · doi:10.1186/s12964-023-01208-y · Cited by 28 · see citing works
Souri, M., Elahi, S., & Soltani, M. (2024) · Expert Opinion on Drug Delivery · doi:10.1080/17425247.2024.2323211 · Cited by 28 · see citing works
A doxorubicin loaded chitosan–poloxamer in situ implant for the treatment of breast cancer
Sahoo, G. P., Rai, V. K., Pradhan, D., Halder, J., Rajwar, T. K., Mahanty, R., Saha, I., Mishra, A., Dash, P., Dash, C., et al. (2024) · RSC Advances · doi:10.1039/d4ra06253a · Cited by 27 · see citing works
Bakri, N. A. C., Kwasnicki, R. M., Dhillon, K., Khan, N., Ghandour, O., Cairns, A., Darzi, A. W., & Leff, D. R. (2021) · Annals of Surgical Oncology · doi:10.1245/s10434-021-10458-4 · Cited by 27 · see citing works
Artificial intelligence supporting cancer patients across Europe—The ASCAPE project
Tzelves, L. I., Manolitsis, I. S., VARKARAKIS, I. M., Ivanović, M. D., Kokkonidis, M., Useros, C. S., Kosmidis, T., Muñoz-Mateu, M., Grau, I., Athanatos, M., et al. (2022) · PLoS ONE · doi:10.1371/journal.pone.0265127 · Cited by 27 · see citing works
Lin, T., Hu, X., Fu, L., Zhang, X., & Chen, H. (2022) · Journal of Clinical Nursing · doi:10.1111/jocn.16321 · Cited by 26 · see citing works
Rapp, S. R., Dressler, E. V. M., Brown, W. M., Wade, J. L., Le-Lindqwister, N. A., King, D. M., Rowland, K. M., Weaver, K. E., Klepin, H. D., Shaw, E. G., et al. (2024) · Journal of Clinical Oncology · doi:10.1200/jco.23.01100 · Cited by 25 · see citing works
Ahmad, N., Alomar, S. Y., Albalawi, F. S., Khan, M. R., Farshori, N. N., Wahab, R., & Shaik, M. R. (2023) · Journal of King Saud University - Science · doi:10.1016/j.jksus.2023.102708 · Cited by 24 · see citing works
Noman, A. M., Sultan, M. T., Zafar, S., Maaz, M., Mazhar, A., Hussain, M., Imran, M., Mujtaba, A., Hussain, M. T., Alsagaby, S. A., et al. (2025) · Food Science & Nutrition · doi:10.1002/fsn3.70936 · Cited by 23 · see citing works
Alessandro de, S. I. R. E., Lippi, L., Ammendolia, A., Cisari, C., Venetis, K., Sajjadi, E., Fusco, N., & Invernizzi, M. (2021) · Journal of Personalized Medicine · doi:10.3390/jpm11121369 · Cited by 23 · see citing works
Bhanushali, A., Tran, L., Nairne-Nagy, J., Bereza, S., Callary, S. A., Atkins, G. J., Ramasamy, B., & Solomon, L. B. (2024) · The Journal of Arthroplasty · doi:10.1016/j.arth.2024.04.053 · Cited by 22 · see citing works
Anticancer Molecular Mechanisms of Epigallocatechin Gallate: An Updated Review on Clinical Trials
Noman, A. M., Sultan, M. T., Mazhar, A., Baig, I., Javaid, J., Hussain, M., Imran, M., Alsagaby, S. A., Abdulmonem, W. A., Mujtaba, A., et al. (2025) · Food Science & Nutrition · doi:10.1002/fsn3.70735 · Cited by 21 · see citing works
Orellana-Jaén, J., Páez, L. C., & Fernández, M. M. (2023) · Breast Cancer · doi:10.1007/s12282-023-01484-z · Cited by 21 · see citing works
Mendes-Santos, C., Nunes, F., Weiderpass, E., Santana, R., & Andersson, G. (2022) · JMIR Cancer · doi:10.2196/33550 · Cited by 19 · see citing works
“Nevertheless, owing to improvements in early diagnosis, tumor molecular characterization, and innovative systemic treatments, breast cancer prognosis has significantly improved across the globe, with 5-year survival rates reaching approximately 90% in high-income countries [3].”
BackgroundHu, L., Xu, B., Chau, P. H., Lok, K. Y. W., Kwok, J. Y. Y., Choi, E. P. H., & Lau, Y. (2024) · Psycho-Oncology · doi:10.1002/pon.9304 · Cited by 18 · see citing works
Kerkmann, A., Schinke, C., Dordevic, A. D., Kern, J., Bangemann, N., Finck, J., Blohmer, J., Ruprecht, K., Göpfert, J. C., Otto, C., et al. (2024) · The Oncologist · doi:10.1093/oncolo/oyae268 · Cited by 18 · see citing works
Han, J., Zhai, X., Tao, X., Li, Y., Zhao, Z., Zhan, Y., Dong, D., Yang, S., & Lv, L. (2025) · Breast Cancer Research · doi:10.1186/s13058-025-02013-w · Cited by 18 · see citing works
Familial aspects of fear of cancer recurrence: current insights and knowledge gaps
Faraji, A., Dehghani, M., & Khatibi, A. (2023) · Frontiers in Psychology · doi:10.3389/fpsyg.2023.1279098 · Cited by 21 · see citing works
The progressive trend of modeling and drug screening systems of breast cancer bone metastasis
Azar, H. K., Gharibshahian, M., Rostami, M., Mansouri, V., Sabouri, L., Beheshtizadeh, N., & Rezaei, N. (2024) · Journal of Biological Engineering · doi:10.1186/s13036-024-00408-5 · Cited by 20 · see citing works
Quality of Life and Hope of Women in China Receiving Chemotherapy for Breast Cancer
Li, Y., Zhou, Z., Ni, N., Li, J., Luan, Z., & Peng, X. (2021) · Clinical Nursing Research · doi:10.1177/10547738211046737 · Cited by 18 · see citing works
Ursini, L. A., Nuzzo, M., Rosa, C., Guglielmo, F. C. D., Tommaso, M. D., Trignani, M., Borgia, M., ALLAJBEJ, A., Patani, F., CARLO, C. D., et al. (2021) · In Vivo · doi:10.21873/invivo.12443 · Cited by 17 · see citing works
Hung, Y., Leung, S., Chiu, S. P., Li, P., Kan, A. C. O., Lo, C., Wong, S. Z., Luk, S., Lai, C. C., Helali, A. E., et al. (2022) · Cancer Medicine · doi:10.1002/cam4.5046 · Cited by 17 · see citing works
Liu, H.-P., Wei, J. C., Yip, H., & Yeh, M.-H. (2021) · Frontiers in Oncology · doi:10.3389/fonc.2021.757626 · Cited by 16 · see citing works
Byun, H. K., Kim, J. S., Chang, J. S., Cho, Y., Ahn, S., Yoon, J. H., Kim, H., Kim, N., Choi, E., Park, H., et al. (2022) · Breast Cancer Research and Treatment · doi:10.1007/s10549-021-06507-x · Cited by 16 · see citing works
Omari, M., Amaadour, L., Zarrouq, B., Al‐Sheikh, Y. A., Asri, A. E., Kriya, S., Nadi, S., Benbrahim, Z., Mellas, N., Rhazi, K. E., et al. (2023) · BMC Women s Health · doi:10.1186/s12905-023-02571-1 · Cited by 16 · see citing works
Age Impacts Clinical and Patient-Reported Outcomes following Postmastectomy Breast Reconstruction
Kim, M., Ali, B., Zhang, K. M., Vingan, P. S., Boe, L. A., Ly, C. L., Allen, R. J., Stern, C. S., Matros, E., Cordeiro, P. G., et al. (2024) · Plastic & Reconstructive Surgery · doi:10.1097/prs.0000000000011554 · Cited by 16 · see citing works
The Key Role of Emotional Repair and Emotional Clarity on Depression among Breast Cancer Survivors
Guil, R., Morales-Sánchez, L., Ruiz-González, P., Gómez-Molinero, R., & Gil-Olarte, P. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph19084652 · Cited by 15 · see citing works
Marwah, H., & Dewangan, H. K. (2025) · Current Cancer Drug Targets · doi:10.2174/0115680096366956250314043513 · Cited by 15 · see citing works
Chou, C.-Y., Shen, T.-T., Wang, W., & Wu, M. (2024) · Taiwanese Journal of Obstetrics and Gynecology · doi:10.1016/j.tjog.2023.11.012 · Cited by 15 · see citing works
Blundo, C., Giroda, M., Fusco, N., Sajjadi, E., Venetis, K., Leonardi, M. C., Vicini, E., Despini, L., Rossi, C. F., Runza, L., et al. (2021) · Frontiers in Oncology · doi:10.3389/fonc.2021.723693 · Cited by 15 · see citing works
Novel sulfonamide-indolinone hybrids targeting mitochondrial respiration of breast cancer cells
Helmy, S. W. A., Abdel‐Aziz, A. K., Dokla, E. M. E., Ahmed, T. E., Hatem, Y., Abdel‐Rahman, E. A., Sharaky, M. M., Shahin, M. I., Elrazaz, E. Z., Serya, R. A. T., et al. (2024) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2024.116255 · Cited by 14 · see citing works
An Updated Review of the Anticancer Mechanisms and Therapeutic Potential of Naringenin
Noman, A. M., Sultan, M. T., Raza, H., Imran, M., Hussain, M., Mujtaba, A., Mostafa, E. M., Ghoneim, M. M., Selim, S., Jaouni, S. K. A., et al. (2025) · Food Science & Nutrition · doi:10.1002/fsn3.70626 · Cited by 13 · see citing works
Nascimben, M., Lippi, L., Alessandro de, S. I. R. E., Invernizzi, M., & Rimondini, L. (2023) · Cancers · doi:10.3390/cancers15020336 · Cited by 13 · see citing works
Validation of the PREDICT Prognostication Tool in US Patients With Breast Cancer
Stabellini, N., Cao, L., Towe, C. W., Miller, M. E., Sousa-Santos, A. H., Amin, A. L., & Montero, A. J. (2023) · Journal of the National Comprehensive Cancer Network · doi:10.6004/jnccn.2023.7048 · Cited by 13 · see citing works
Zeng, Q., Li, C., Yu, T., & Zhang, H. (2024) · American Journal of Physical Medicine & Rehabilitation · doi:10.1097/phm.0000000000002531 · Cited by 13 · see citing works
Darida, M., Rubovszky, G., Kiss, Z., Székely, B., Madaras, B., Horváth, Z., Kocsis, J., Sipőcz, I., Várnai, M., Balogh, É., et al. (2025) · Frontiers in Oncology · doi:10.3389/fonc.2025.1465511 · Cited by 13 · see citing works
Intrieri, T., Manneschi, G., & Caldarella, A. (2022) · Journal of Cancer Research and Clinical Oncology · doi:10.1007/s00432-022-04245-1 · Cited by 12 · see citing works
A Framework for Breast Cancer Classification with Deep Features and Modified Grey Wolf Optimization
P., F. R. P., & Tehsin, S. (2025) · Mathematics · doi:10.3390/math13081236 · Cited by 12 · see citing works
Fusco, N., Rizzo, A., Costarelli, L., Santinelli, A., Cerbelli, B., Scatena, C., Macrì, E., Pietribiasi, F., d’Amati, G., Sapino, A., et al. (2022) · Pathologica · doi:10.32074/1591-951x-747 · Cited by 12 · see citing works
Eugenol: An Insight Into the Anticancer Perspective and Pharmacological Aspects
Noman, A. M., Sultan, M. T., Mazhar, A., Khan, W. A., Imran, M., Hussain, M., Mostafa, E. M., El-Ghorab, A. H., Ghoneim, M. M., Selim, S., et al. (2025) · Food Science & Nutrition · doi:10.1002/fsn3.70727 · Cited by 11 · see citing works
Hybrid Optimization and Explainable Deep Learning for Breast Cancer Detection
Mustafa, M. A., Erdem, O. A., & Söğüt, E. (2025) · Applied Sciences · doi:10.3390/app15158448 · Cited by 11 · see citing works
Kang, D., Kim, H., Cho, J., Kim, Z., Chung, M., Lee, J. E., Nam, S. J., Kim, S. W., Yu, J., Chae, B. J., et al. (2023) · JMIR Public Health and Surveillance · doi:10.2196/45212 · Cited by 11 · see citing works
Synergistic strength: unleashing exercise and polyphenols against breast cancer
Pang, H., & Badehnoosh, B. (2025) · Cancer Cell International · doi:10.1186/s12935-025-03767-1 · Cited by 11 · see citing works
Cytotoxic and molecular assessment against breast (MCF-7) cancer cells with cobalt oxide nanoballs
Wahab, R., Siddiqui, M. A., Ahmad, J., Saquib, Q., & Al-Khedhairy, A. A. (2021) · Journal of King Saud University - Science · doi:10.1016/j.jksus.2021.101467 · Cited by 10 · see citing works
Bozal, R. G., Ruíz-González, P., Morales-Sánchez, L., Gómez‐Molinero, R., & Márquez, P. G.-O. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph19148592 · Cited by 12 · see citing works
Postpartum Breast Cancer and Survival in Women With Germline BRCA Pathogenic Variants
Zhang, Z., Ye, S., Bernhardt, S. M., Nelson, H. D., Velie, E. M., Borges, V. F., Woodward, E. R., Evans, D. G., & Schedin, P. J. (2024) · JAMA Network Open · doi:10.1001/jamanetworkopen.2024.7421 · Cited by 13 · see citing works
Mechanisms of traditional Chinese medicine overcoming of radiotherapy resistance in breast cancer
Zhao, X., Luo, T., Qiu, Y., Yang, Z., Wang, D., Wang, Z., Zeng, J., & Bi, Z. (2024) · Frontiers in Oncology · doi:10.3389/fonc.2024.1388750 · Cited by 9 · see citing works
Comprehensive review of non-invasive-treatment-related cardiovascular toxicity in breast cancer
Li, C., Dai, H., Guo, X., Zhou, L., & Jiang, M. (2025) · iScience · doi:10.1016/j.isci.2025.111759 · Cited by 9 · see citing works
Kastora, S. L., Pantiora, E. V., Hong, Y. H., Veeramani, M., Azim, H. A., Chakrabarti, R., Geisler, J., Knoop, A. S., Lambertini, M., Linderholm, B. K., et al. (2025) · Cancer Treatment Reviews · doi:10.1016/j.ctrv.2025.102880 · Cited by 9 · see citing works
Haris, I., Hutajulu, S. H., Astari, Y. K., Wiranata, J. A., Widodo, I., Kurnianda, J., Taroeno‐Hariadi, K. W., Hardianti, M. S., Purwanto, I., & Prabandari, Y. S. (2023) · Cureus · doi:10.7759/cureus.41744 · Cited by 9 · see citing works
Munzone, E., Marra, A., Comotto, F., Guercio, L., Sangalli, C. A., Cascio, M. L., Pagan, E., Sangalli, D., Bigoni, I., Porta, F. M., et al. (2024) · JCO Clinical Cancer Informatics · doi:10.1200/cci.24.00034 · Cited by 9 · see citing works
Vrieling, C., Assele, S. Y., Moser, L. C., Sauvé, N., Litière, S., Fourquet, A., Poortmans, P. M., Struikmans, H., van Tienhoven, G., Bartelink, H. G. M. M., et al. (2021) · European Journal of Cancer · doi:10.1016/j.ejca.2021.06.018 · Cited by 9 · see citing works
Post-mastectomy Pain Syndrome: A Review Article and Emerging Treatment Modalities
Shah, J. D., Kirkpatrick, K. P., & Shah, K. B. (2024) · Cureus · doi:10.7759/cureus.56653 · Cited by 8 · see citing works
Dong, J., Wang, D., & Zhong, S. (2024) · PLoS ONE · doi:10.1371/journal.pone.0300176 · Cited by 12 · see citing works
The effect of sleep quality on attitudes toward death in breast cancer survivors
Düzova, Ü. S., Düzova, M., & Altınel, B. (2024) · Supportive Care in Cancer · doi:10.1007/s00520-024-08865-w · Cited by 8 · see citing works
Colaes, R., Schroyen, G., Radwan, A., Laic, R. A. G., Helsper, S., Himmelreich, U., Hatse, S., Smeets, A., Caeyenberghs, K., Sunaert, S., et al. (2025) · Cancer · doi:10.1002/cncr.70095 · Cited by 8 · see citing works
Artificial intelligence for breast cancer management
Chua, B. N., Thng, D. K. H., Toh, T. B., & Ho, D. (2026) · Communications Medicine · doi:10.1038/s43856-025-01342-3 · Cited by 9 · see citing works
Acceptance of Artificial Intelligence in Supporting Cancer Patients
Manolitsis, I. S., Tzelves, L. I., Feretzakis, G., Kalles, D., Verykios, V. S., Katsimperis, S. N., Αναστασίου, Α., Koutsouris, D., Kosmidis, T., Deliveliotis, C., et al. (2023) · Studies in health technology and informatics · doi:10.3233/shti230561 · Cited by 8 · see citing works
Baseline quality of life and chemotherapy toxicities in patients with early breast cancer
Licaj, I., Coquan, E., Dabakuyo‐Yonli, T. S., Dauchy, S., Vaz-Luís, I., Charles, C., Lemogne, C., Trédan, O., Vanlemmens, L., Jouannaud, C., et al. (2023) · Cancer · doi:10.1002/cncr.34643 · Cited by 7 · see citing works
Qin, Q., Li, S., Li, W., & Li, Y. (2023) · Journal of Clinical Psychology · doi:10.1002/jclp.23584 · Cited by 7 · see citing works
Oncoplastic breast surgery in Europe
Däster, K., García, R. P., Masannat, Y., & Kothari, A. S. (2024) · Gland Surgery · doi:10.21037/gs-23-380 · Cited by 7 · see citing works
Xu, W., Liu, X., Zhang, C., Zhu, L., Zhao, Y., & Liao, C. (2024) · Asian Nursing Research · doi:10.1016/j.anr.2024.09.003 · Cited by 7 · see citing works
Alessandro de, S. I. R. E., Lippi, L., Marotta, N., Folli, A., Calafiore, D., Moalli, S., Turco, A., Ammendolia, A., Fusco, N., & Invernizzi, M. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24020921 · Cited by 7 · see citing works
Song, B., Hou, G., Xu, M., & Chen, M. (2024) · Cellular Signalling · doi:10.1016/j.cellsig.2024.111101 · Cited by 7 · see citing works
Caprara, G., Pagan, E., Titta, L., Tieri, M., Magionesi, G., Gallosti, S., Bagnardi, V., Mazzocco, K., & Mazza, M. (2024) · Frontiers in Oncology · doi:10.3389/fonc.2024.1436610 · Cited by 6 · see citing works
- Authors
- Nardin, S., Mora, E., Varughese, F. M., D'Avanzo, F., Vachanaram, A. R., Rossi, V., Saggia, C., Rubinelli, S., & Gennari, A.
- Affiliations
- Università degli Studi del Piemonte Orientale “Amedeo Avogadro” (IT)
- Azienda Ospedaliero Universitaria Maggiore della Carita (IT)
- Corresponding author
- Gennari, Alessandra
- Venue
- Frontiers in Oncology
- Publisher
- Frontiers Media SA
- Published
- 2020-06-16
- Volume
- 10
- Pages
- 864-864
- ISSN
- 2234-943X (ISSN-L)
- PMC
- PMC7308500
- OpenAlex
- W3036457113
- Cited by
- 330
- References
- 39
- Citations by year
- 2026: 47 · 2025: 85 · 2024: 83 · 2023: 55 · 2022: 37 · 2021: 21 · 2020: 2
- FWCI
- 3.09
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Frontiers in Oncology (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- Associazione Italiana per la Ricerca sul Cancro
- Topics
- Health Sciences › Medicine › Oncology › Cancer survivorship and care
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cancer Research › Breast Cancer Treatment Studies
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Childhood Cancer Survivors' Quality of Life
- Keywords
- breast cancer survivorship, quality of life, late toxicity, breast cancer screening, breast cancer subtypes, targeted therapy, personalized treatment
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