The Mechanism of Warburg Effect-Induced Chemoresistance in Cancer

Cites (244)

Items 201–244 of 244

1. Hypoxia favors chemoresistance in T-ALL through an HIF1α-mediated mTORC1 inhibition loop
   Lucine Fahy, Julien Calvo, Sara Chabi, Laurent Renou, Charly Le Maout, Sandrine Poglio, Thierry M Leblanc, Arnaud Petit, André Baruchel, Paola Fabiola Ballerini et al. · 2021 · Blood Advances
2. Fam83D promotes tumorigenesis and gemcitabine resistance of pancreatic adenocarcinoma through the Wnt/β-catenin pathway
   Yongqiang Hua, Ke Zhang, Jie Sheng, Zhouyu Ning, Ye Li, Weidong Shi, Luming Liu · 2021 · Life Sciences
3. Tumor Microenvironment – Selective Pressures Boosting Cancer Progression
   Sofia C. Nunes · 2020 · Advances in experimental medicine and biology
4. Targeting Cellular Metabolism Chemosensitizes the Doxorubicin-Resistant Human Breast Adenocarcinoma Cells
   Shulan Ma, Rongfei Jia, Dongju Li, Bo Shen · 2015 · BioMed Research International
5. Could GLUT12 be a Potential Therapeutic Target in Cancer Treatment? A Preliminary Report
   Jonai Pujol‐Giménez, Fátima Pérez de Heredia, Miguel Angel Idoate · 2015 · Journal of Cancer
6. Metformin facilitates BG45‑induced apoptosis via an anti‑Warburg effect in cholangiocarcinoma cells
   Dehua Tang, Lei Xu, Mingming Zhang, Robert Dorfman, Yida Pan, Qian Zhou, Lixing Zhou, Yuming Wang, Yang Li, Yuyao Yin et al. · 2018 · Oncology Reports
7. Helicobacter pylori CagA Protein Attenuates 5-Fu Sensitivity of Gastric Cancer Cells Through Upregulating Cellular Glucose Metabolism
   Sujie Gao, Defeng Song, Yiting Liu, Hongwei Yan, Xuebo Chen · 2020 · OncoTargets and Therapy
8. Liposomes co-Loaded with 6-Phosphofructo-2-Kinase/Fructose-2, 6-Biphosphatase 3 (PFKFB3) shRNA Plasmid and Docetaxel for the Treatment of non-small Cell Lung Cancer
   Nusrat Chowdhury, I. Vhora, Ketan Patel, R. Doddapaneni, A. Mondal, Mandip Singh · 2017 · Pharmaceutical Research
9. Metabolic Interplay between Tumour Cells and Cancer-Associated Fibroblasts (CAFs) under Hypoxia versus Normoxia
   Septelia Inawati Wanandi, Sri Suciati Ningsih, Hijrah Asikin, Rendy Hosea, Gladies Mercya Grameinie Neolaka · 2018 · Malaysian Journal of Medical Sciences
10. Hypoxia exposure induced cisplatin resistance partially via activating p53 and hypoxia inducible facor‑1α in non‑small cell lung cancer A549 cells
    Qiang Guo, Fei Lan, Yan Xu, Xiao Zhu, Yuelei Wu, Qin Zhang · 2018 · Oncology Letters
11. Combined deletion of Glut1 and Glut3 impairs lung adenocarcinoma growth
    Caroline Contat, Pierre‐Benoit Ancey, Nadine Zangger, Silvia Sabatino, Justine Pascual, Stéphane Escrig, Louise Helene Søgaard Jensen, Christine Goepfert, Bernard Lanz, Mario G. Lepore et al. · 2020 · eLife
12. YAP promotes the proliferation and migration of colorectal cancer cells through the Glut3/AMPK signaling pathway
    Lin‐Hua Jiang, Jiawen Zhang, Qixuan Xu, Bin Wang, Yizhou Yao, Liang Sun, Xuchao Wang, Diyuan Zhou, Ling Gao, Shiduo Song et al. · 2021 · Oncology Letters
13. Tumor-Derived Exosome-Educated Hepatic Stellate Cells Regulate Lactate Metabolism of Hypoxic Colorectal Tumor Cells via the IL-6/STAT3 Pathway to Confer Drug Resistance
    Feifei Li, Lei Zhan, Qian Dong, Qiwei Wang, Yuanhe Wang, Xiaoyan Li, Yong Zhang, Jingdong Zhang · 2020 · OncoTargets and Therapy
14. Sphingosine kinase 1 contributes to doxorubicin resistance and glycolysis in osteosarcoma
    Xiaojun Ren, Chunhong Su · 2020 · Molecular Medicine Reports
15. Targeting the autophagy in bone marrow stromal cells overcomes resistance to vorinostat in chronic lymphocytic leukemia
    Lu Ding, Wan Zhang, Lili Yang, Hélène Pelicano, Kaiwen Zhou, Ran Yin, Ruibin Huang, Junyi Zeng · 2018 · OncoTargets and Therapy
16. Neoadjuvant Chemotherapy in Breast Cancer: Review of the Evidence and Conditions That Facilitated Its Use during the Global Pandemic
    Tabitha Tse, Sandeep R. Sehdev, Jean Morag Seely, Denis H. Gravel, Mark J. Clemons, Erin Cordeiro, Angel Arnaout · 2021 · Current Oncology
17. Targeting monocarboxylate transporter by α-cyano-4-hydroxycinnamate modulates apoptosis and cisplatin resistance of Colo205 cells: implication of altered cell survival regulation
    Ajay Kumar, Shiva Kant, Sukh Mahendra Singh · 2013 · APOPTOSIS
18. Knockdown of FOXO6 Inhibits Glycolysis and Reduces Cell Resistance to Paclitaxel in HCC Cells via PI3K/Akt Signaling Pathway
    Xixiang Yu, Xixi Gao, Xiaoping Mao · 2020 · OncoTargets and Therapy
19. MYC Expression and Metabolic Redox Changes in Cancer Cells: A Synergy Able to Induce Chemoresistance
    Barbara Marengo, Ombretta Garbarino, Andrea Speciale, Lorenzo Monteleone, Nicola Traverso, Cinzia Domenicotti · 2019 · Oxidative Medicine and Cellular Longevity
20. Emetine elicits apoptosis of intractable B-cell lymphoma cells with MYC rearrangement through inhibition of glycolytic metabolism
    Tomohiro Aoki, Kazuyuki Shimada, Akihiko Sakamoto, Keiki Sugimoto, Takanobu Morishita, Yuki Kojima, Satoko Shimada, Seiichi X. Kato, Chisako Iriyama, Shunsuke Kuno et al. · 2016 · Oncotarget
21. Effect of pyruvate kinase M2-regulating aerobic glycolysis on chemotherapy resistance of estrogen receptor-positive breast cancer
    Yue-jun Qian, Lina Bi, Yingxu Yang, Dong Wang · 2018 · Anti-Cancer Drugs
22. MicroRNA‐488 inhibits proliferation and glycolysis in human prostate cancer cells by regulating PFKFB3
    Jun Wang, Xiaojuan Li, Zhaoming Xiao · 2019 · FEBS Open Bio
23. Effects of extracellular acidity on resistance to chemotherapy treatment: a systematic review
    Viviane Palmeira da Silva, Carulina Bueno de Mesquita, Júlia Silveira Nunes · 2018 · Medical Oncology
24. Overcoming cetuximab resistance in Ewing's sarcoma by inhibiting lactate dehydrogenase-A
    JIAXIN FU, HAN JIANG, Chenxuan Wu · 2016 · Molecular Medicine Reports
25. Ammonia mediates mitochondrial uncoupling and promotes glycolysis via HIF-1 activation in human breast cancer MDA-MB-231 cells
    Yapeng Lu, Lu Wang, Wangwang Ding, Dan Wang, Xueting Wang, Qianqian Luo, Li Zhu · 2019 · Biochemical and Biophysical Research Communications
26. Glycolytic inhibition by 3-bromopyruvate increases the cytotoxic effects of chloroethylnitrosoureas to human glioma cells and the DNA interstrand cross-links formation
    Xiaodong Sun, Guohui Sun, Yaxin Huang, Shufen Zhang, Xiaoyu Tang, Na Zhang, Lijiao Zhao, Rugang Zhong, Yongzhen Peng · 2020 · Toxicology
27. Targeting glycometabolic reprogramming to restore the sensitivity of leukemia drug-resistant K562/ADM cells to adriamycin
    Xueyan Zhang, Jing Chen, Ziying Ai, Zhewen Zhang, Li Lin, Hulai Wei · 2018 · Life Sciences
28. Intratumoral Distribution of Lactate and the Monocarboxylate Transporters 1 and 4 in Human Glioblastoma Multiforme and Their Relationships to Tumor Progression-Associated Markers
    Carolin Kubelt, Sönke Peters, Hajrullah Ahmeti, Monika Huhndorf, Lukas Huber, Gesa Cohrs, Jan‐Bernd Hövener, Olav Jansen, Michael Synowitz, Janka Held‐Feindt · 2020 · International Journal of Molecular Sciences
29. MicroRNA‑122 regulates docetaxel resistance of prostate cancer cells by regulating PKM2
    Zhirong Zhu, Guiliang Tang, Jiajun Yan · 2020 · Experimental and Therapeutic Medicine
30. Disruption of pH Dynamics Suppresses Proliferation and Potentiates Doxorubicin Cytotoxicity in Breast Cancer Cells
    Diana Tavares‐Valente, Bárbara Sousa, Fernando Carlos Schmitt, Fátima Baltazar, Odília Queirós · 2021 · Pharmaceutics
31. Nodal induced by hypoxia exposure contributes to dacarbazine resistance and the maintenance of stemness in melanoma cancer stem‑like cells
    Hong Li, Junjie Chen, Xiao Wang · 2018 · Oncology Reports
32. Circular RNA circUBE2D2 functions as an oncogenic factor in hepatocellular carcinoma sorafenib resistance and glycolysis.
    Hai Huang, Jian Wei Peng, Shijian Yi · 2021 · PubMed
33. Synergistic cytotoxicity of cisplatin and Taxol in overcoming Taxol resistance through the inhibition of LDHA in oral squamous cell carcinoma
    Lin Feng, E Lingling, MICHAIL MICHAILOVICH SOLOVEIV, Dongsheng Wang, Bo Zhang, Yu Dong, Hong‐Chen Liu · 2015 · Oncology Letters
34. Down-Regulation of miR-7 in Gastric Cancer Is Associated With Elevated LDH-A Expression and Chemoresistance to Cisplatin
    Huifang Jin, Jufeng Wang, Ming Shao · 2020 · Frontiers in Cell and Developmental Biology
35. Impact of Hypoxia-Related Tumor Acidosis on Cytotoxicity of Different Chemotherapeutic Drugs In Vitro and In Vivo
    Oliver Thews, Anne Riemann, Martin Nowak, Michael Gekle · 2014 · Advances in experimental medicine and biology
36. A specific inhibitor of lactate dehydrogenase overcame the resistance toward gemcitabine in hypoxic mesothelioma cells, and modulated the expression of the human equilibrative transporter-1
    Elisa Giovannetti, Leticia G. León, Valentina E. Gómez‐Mellado, Paolo Andrea Zucali, Filippo Minutolo, Godefridus J. Peters · 2016 · Nucleosides Nucleotides & Nucleic Acids
37. PPARα agonist alleviates tumor growth and chemo-resistance associated with the inhibition of glucose metabolic pathway
    Qian Gou, Dong Chen, Jianhua Jin · 2019 · European Journal of Pharmacology
38. Potential Roles of GLUT12 for Glucose Sensing and Cellular Migration in MCF-7 Human Breast Cancer Cells Under High Glucose Conditions
    CHIHIRO MATSUI, Tomoka Takatani‐Nakase, Sachie Maeda · 2017 · Anticancer Research
39. Ascorbate sensitizes human osteosarcoma cells to the cytostatic effects of cisplatin
    Naohiro Oka, Akiyoshi Komuro, Hisayuki Amano, Suman Dash, Masahiko Honda, Kazushige Ota, Shunji Nishimura, Takeshi Ueda, Masao Akagi, Hitoshi Okada · 2020 · Pharmacology Research & Perspectives
40. Targeting Altered Metabolism—Emerging Cancer Therapeutic Strategies
    Minsuh Seo, Robert Blake Crochet, Yong‐Hwan Lee · 2014 · Elsevier eBooks
41. Targeting PFKFB3 in the Endothelium for Cancer Therapy
    Qi Yang, Peng Hou · 2017 · Trends in Molecular Medicine
42. Silencing TCF4 Sensitizes Melanoma Cells to Vemurafenib Through Inhibiting GLUT3-Mediated Glycolysis
    Can Liu, Siqi He, Jianfei Zhang, Shiyan Li, Jian Chen, Chaofei Han · 2020 · OncoTargets and Therapy
43. TRIM66 Overexpression Promotes Glioma Progression and Regulates Glucose Uptake Through cMyc/GLUT3 Signaling
    Yuequn Song, Lifang Meng, Jian Qing Yu · 2021 · Cancer Management and Research
44. Expression of Glycolysis-Related Proteins in Cancer of Unknown Primary Origin
    Murilo Bonatelli, Isabella Fernandes Fornari, Priscila Neves Bernécule, Lara Esquiapatti Pinheiro, Ricardo Filipe Alves Costa, Adhemar Longatto‐Filho, João Neif Antonio, Eduardo Caetano Albino da Silva, Flavio Mavignier Cárcano, Celine Marques Pinheiro · 2021 · Frontiers in Oncology