Gut Microbiota-Dependent Metabolite Trimethylamine N-Oxide Contributes to Cardiac Dysfunction in Western Diet-Induced Obese Mice

Cited by (280)

Items 101–200 of 280

1. Ginger essential oil and citral ameliorates atherosclerosis in ApoE−/− mice by modulating trimethylamine-N-oxide and gut microbiota
   Suraphan Panyod, Wei‐Kai Wu, Sin-Yi Peng, Yea-Jing Tseng, Ya-Chi Hsieh, Rou-An Chen, Huai‐Syuan Huang, Yi‐Hsun Chen, Hsiao-Li Chuang, Cheng‐Chih Hsu et al. · 2023 · npj Science of Food
2. Connections between serum Trimethylamine N-Oxide (TMAO), a gut-derived metabolite, and vascular biomarkers evaluating arterial stiffness and subclinical atherosclerosis in children with obesity
   Monica Simina Mihuţa, Corina Paul, Andreea Borlea, Cristina Mihaela Roi, Denisa Pescari, Oana-Alexandra Velea-Barta, Ioana Monica Mozos, Dana Liana Stoian · 2023 · Frontiers in Endocrinology
3. Reductions in gut microbiota‑derived metabolite trimethylamine N‑oxide in the circulation may ameliorate myocardial infarction‑induced heart failure in rats, possibly by inhibiting interleukin‑8 secretion
   Xiaoyan Li, Yongcun Sun, Xinru Zhang, Jing Wang · 2019 · Molecular Medicine Reports
4. Trimethylamine-N-oxide acutely increases cardiac muscle contractility
   Carlee I. Oakley, Julian A. Vallejo, Derek D. Wang, Mark Gray, LeAnn M. Tiede-Lewis, Tilitha Shawgo, Emmanuel Daon, George L. Zorn, Jason R. Stubbs, Michael Wacker · 2020 · American Journal of Physiology-Heart and Circulatory Physiology
5. Adopting a Mediterranean-style eating pattern with low, but not moderate, unprocessed, lean red meat intake reduces fasting serum trimethylamine N-oxide (TMAO) in adults who are overweight or obese
   Sridevi Krishnan, Lauren E O’Connor, Yu Han Daisy Wang, Erik Gertz, Wayne W. Campbell, Brian J. Bennett · 2021 · British Journal Of Nutrition
6. Fasting-Mimicking Diet Reduces Trimethylamine N-Oxide Levels and Improves Serum Biochemical Parameters in Healthy Volunteers
   Melita Videja, Eduards Sevostjanovs, Sabīne Upmale-Engela, Edgars Liepinsh, Ilze Konrāde, Maija Dambrova · 2022 · Nutrients
7. Gut Microbiota and Coronary Artery Disease: Current Therapeutic Perspectives
   Themistoklis Katsimichas, Panagiotis Theofilis, Konstantinos P Tsioufis, Dimitris Tousoulis · 2023 · Metabolites
8. Alteration of the gut microbiome in patients with heart failure: A systematic review and meta-analysis
   Jiayi Huang, Yongping Lin, Xiangwei Ding, Song Lin, Xin Li, Wei Yan, Minglong Chen · 2024 · Microbial Pathogenesis
9. The gut microbiota and cardiovascular disease: Exploring the role of microbial dysbiosis and metabolites in pathogenesis and therapeutics
   Amin Mohsenzadeh, Sahar Pourasgar, Amirali Mohammadi, Mahdis Nazari, Soroush Nematollahi, Yeganeh Karimi, Parisa Firoozbakhsh, Hossein Mohsenzadeh, Kasra Kamali, Reza Elahi · 2025 · Life Sciences
10. Microbiome-Derived Trimethylamine N-Oxide (TMAO) as a Multifaceted Biomarker in Cardiovascular Disease: Challenges and Opportunities
    Kinga Jaworska, Wojciech Kopacz, Mateusz Koper, Marcin Ufnal · 2024 · International Journal of Molecular Sciences
11. Systematic investigation of the relationships of trimethylamine N -oxide and l -carnitine with obesity in both humans and rodents
    Xiang Gao, Guang Sun, Edward W. Randell, Yuan Tian, Haicheng Zhou · 2020 · Food & Function
12. Identification of Potential Biomarkers in the Cervicovaginal Fluid by Metabolic Profiling for Preterm Birth
    AbuZar Ansari, Heeyeon Lee, Young‐Ah You, Youngae Jung, Sunwha Park, Soo Min Kim, Geum‐Sook Hwang, Young Ju Kim · 2020 · Metabolites
13. Gut Microbiota and the Quality of Oral Anticoagulation in Vitamin K Antagonists Users: A Review of Potential Implications
    Anny J. Camelo-Castillo, José Miguel Rivera‐Caravaca, Esteban Orenes‐Piñero, Inmaculada Ramírez-Macías, Vanessa Roldán, Gregory Y.H. Lip, Francisco R. Marín · 2021 · Journal of Clinical Medicine
14. Suppression of trimethylamine N-oxide with DMB mitigates vascular dysfunction, exercise intolerance, and frailty associated with a Western-style diet in mice
    Vienna Elizabeth Brunt, Nathan Greenberg, Zachary J. Sapinsley, Abigail G. Casso, James J. Richey, Nicholas S. VanDongen, Rachel A. Gioscia‐Ryan, Brian P. Ziemba, Andrew Peter Neilson, Kevin P. Davy et al. · 2022 · Journal of Applied Physiology
15. Increased Trimethylamine N-Oxide Is Not Associated with Oxidative Stress Markers in Healthy Aged Women
    Robert Antoni Olek, Joanna J. Samulak, Angelika Katarzyna Sawicka, Dace Hartmane, Solveiga Grı̄nberga, Osvalds Pugovičs, Wiesława Łysiak−Szydłowska · 2019 · Oxidative Medicine and Cellular Longevity
16. wild-type choline TMA lyase in complex with betaine aldehyde
    Michael A. Funk, Catherine Luschinsky Drennan · 2018 · Worldwide Protein Data Bank
17. Gut microbiota nexus: Exploring the interactions with the brain, heart, lungs, and skin axes and their effects on health
    Pallab Chakraborty, Debolina Banerjee, Paramita Majumder, Joy Sarkar · 2024 · Medicine in Microecology
18. Obesity-associated inflammation countered by a Mediterranean diet: the role of gut-derived metabolites
    Melanie R. Florkowski, Esther Abiona, Karen M. Frank, Allison L. Brichacek · 2024 · Frontiers in Nutrition
19. Targeting on Gut Microbiota-Derived Metabolite Trimethylamine to Protect Adult Male Rat Offspring against Hypertension Programmed by Combined Maternal High-Fructose Intake and Dioxin Exposure
    Chien‐Ning Hsu, Julie Y.H. Chan, Hong‐Ren Yu, Wei‐Chia Lee, Kay L. H. Wu, Guo‐Ping Chang‐Chien, Sufan Lin, Chih‐Yao Hou, You‐Lin Tain · 2020 · International Journal of Molecular Sciences
20. A Novel Insight at Atherogenesis: The Role of Microbiome
    Tatiana Vladimirovna Kirichenko, Yuliya V. Markina, Vasily N. Sukhorukov, Victoria Alexandrovna Khotina, Wei‐Kai Wu, Alexander Nikolaevich Orekhov · 2020 · Frontiers in Cell and Developmental Biology
21. Targeting Gut Microbiota as a Novel Strategy for Prevention and Treatment of Hypertension, Atrial Fibrillation and Heart Failure: Current Knowledge and Future Perspectives
    Oxana M. Drapkina, Adel A. Yafarova, A. N. Kaburova, Anton R. Kiselev · 2022 · Biomedicines
22. The Interaction of Gut Microbiota and Heart Failure with Preserved Ejection Fraction: From Mechanism to Potential Therapies
    Wei Yu, Yufeng Jiang, Hui Xu, Yafeng Zhou · 2023 · Biomedicines
23. Cabernet sauvignon dry red wine ameliorates atherosclerosis in mice by regulating inflammation and endothelial function, activating AMPK phosphorylation, and modulating gut microbiota
    Xinlong Cheng, Xue Han, Liangfu Zhou, Yasai Sun, Qian Zhou, Xuan Lin, Zhe Gao, Jie Wang, Wen Zhao · 2023 · Food Research International
24. Gut Microbe-Generated Metabolite Trimethylamine-N-Oxide and Ischemic Stroke
    Zhen Li, Xinyi He, Qi Fang, Xulong Yin · 2024 · Biomolecules
25. The interplay between microbial metabolites and macrophages in cardiovascular diseases: A comprehensive review
    Yongzheng Yang, Sajad Karampoor, Rasoul Mirzaei, Л. Л. Бороздкин, Ping Zhu · 2023 · International Immunopharmacology
26. Relationship between disorders of the intestinal microbiota and heart failure in infants with congenital heart disease
    Qi‐Liang Zhang, Xiuhua Chen, Si‐Jia Zhou, Yuqing Lei, Jiang-Shan Huang, Qiang Chen, Hua Cao · 2023 · Frontiers in Cellular and Infection Microbiology
27. Trimethylamine-N-oxide promotes osteoclast differentiation and oxidative stress by activating NF-κB pathway
    Yangyang Zhao, Chizhen Wang, Fei Qiu, Jing Liu, Yujuan Xie, Zhengkun Lin, Jianquan He, Jian Chen · 2024 · Aging
28. Trimethylamine N-Oxide (TMAO) and cancer risk: Insights into a possible link
    Biki Saha, Antara Banerjee, Rupak Pathak, Asim K. Duttaroy, Surajit Pathak · 2025 · Biomedicine & Pharmacotherapy
29. The mechanisms underlying acute myocardial infarction in chronic kidney disease patients undergoing hemodialysis
    Yujie Zhu, Yu-Chen Lai, Yuxuan Hu, Yiwen Fu, Zheng Zhang, Nan Lin, Wei Huang, Lemin Zheng · 2024 · Biomedicine & Pharmacotherapy
30. The Role of the Microbiota in the Diabetic Peripheral Artery Disease
    Federico Biscetti, Elisabetta Nardella, Andrea Leonardo Cecchini, Raffaele Landolfi, Andrea Flex · 2019 · Mediators of Inflammation
31. Comparison of Microbial Populations in the Blood of Patients With Myocardial Infarction and Healthy Individuals
    Ikram Khan, Imran Khan, Mian Adnan Kakakhel, Zhang Xiaowei, Ting Mao, Ikram Ali, Yu Fei, Zhou Jianye, Zhiqiang Li, Lizhe An · 2022 · Frontiers in Microbiology
32. The gut microbe-derived metabolite trimethylamine-N-oxide induces aortic valve fibrosis via PERK/ATF-4 and IRE-1α/XBP-1s signaling in vitro and in vivo
    Zhenyu Xiong, Jiaying Li, Rihua Huang, Huimin Zhou, Xingfeng Xu, Shaozhao Zhang, Peihan Xie, Miaohong Li, Yue Guo, Xinxue Liao et al. · 2023 · Atherosclerosis
33. Towards a Large-Scale Assessment of the Relationship Between Biological and Chronological Aging: The Inspire Mouse Cohort
    Yohan Santin, S. Lopez, Isabelle Ader, Sandrine Andrieu, Nicolas Blanchard, Audrey Carrière, Louis Casteilla, Béatrice Cousin, Noélie Davezac, Philipe de Souto Barreto et al. · 2021 · The Journal of Frailty & Aging
34. Role of Gut Microbial Metabolites in Ischemic and Non-Ischemic Heart Failure
    Mohammad Reza Hatamnejad, Lejla Medzikovic, Ateyeh Dehghanitafti, Bita Rahman, Arjun Vadgama, Mansoureh Eghbali · 2025 · International Journal of Molecular Sciences
35. Loop Diuretics Inhibit Renal Excretion of Trimethylamine N-Oxide
    Daniel Yuhang Li, Zeneng Wang, Xun Jia, Di Yan, Diana M. Shih, Stanley L. Hazen, Aldons Jake Lusis, W.H. Wilson Tang · 2021 · JACC Basic to Translational Science
36. Benefits of Biotics for Cardiovascular Diseases
    Emília Hijová · 2023 · International Journal of Molecular Sciences
37. Gut microbiota and integrative traditional Chinese and western medicine in prevention and treatment of heart failure
    Herong Cui, Songjie Han, Yanan Dai, Wei Xie, Rui Zheng, Yang Sun, Xiaofeng Xia, Xiaopeng Deng, Yaru Cao, Mei Zhang et al. · 2023 · Phytomedicine
38. The Influence of an Epigenetics Diet on the Cancer Epigenome
    Kayla A. Lewis, Trygve O. Tollefsbol · 2017 · Epigenomics
39. TMAO promotes apoptosis and oxidative stress of pancreatic acinar cells by mediating IRE1α-XBP-1 pathway
    Guodong Yang, Xiaoying Zhang · 2021 · Saudi Journal of Gastroenterology
40. Probiotics as potential treatments to reduce myocardial remodelling and heart failure via the gut-heart axis: State-of-the-art review
    Morris Karmazyn, Xiaohong Tracey Gan · 2023 · Molecular and Cellular Biochemistry
41. The Role of Gut Microbiota in Host Lipid Metabolism: An Eye on Causation and Connection
    Kai Wang, Xianyi Liang, Yanli Pang, Changtao Jiang · 2019 · Small Methods
42. Gut microbiota influence frailty syndrome in older adults: mechanisms and therapeutic strategies
    Xiaoming Wang, Lu Fan, Chenchen Meng, Yunjiao Wang, Li-E Deng, Zhuo Yuan, Junping Zhang, Yanyang Li, Shichao Lv · 2023 · Biogerontology
43. The Role of Gut and Airway Microbiota in Pulmonary Arterial Hypertension
    Linlin Huang, Hongdie Zhang, Yijun Liu, Yang Long · 2022 · Frontiers in Microbiology
44. Trimethylamine N-oxide: role in cell senescence and age-related diseases
    Lin Zhang, Fang Yu, Jian Xia · 2022 · European Journal of Nutrition
45. Gut Microbiota and Cardiovascular System: An Intricate Balance of Health and the Diseased State
    Mujtaba Aamir Bhat, Awdhesh Kumar Mishra, Javeed Ahmad Tantray, Hanan Ali Alatawi, Mοhd Saeed, Safikur Rahman, Arif Tasleem Jan · 2022 · Life
46. Trimethylamine N-Oxide as a Mediator Linking Peripheral to Central Inflammation: An In Vitro Study
    Manuel H. Janeiro, Maite Solas, Josune Orbe, José Antonio Rodríguez, Leyre Sánchez de Muniain, Paula Escalada, Ping Kei Yip, María Javier Ramírez · 2023 · International Journal of Molecular Sciences
47. The Presence of High Levels of Circulating Trimethylamine N-Oxide Exacerbates Central and Peripheral Inflammation and Inflammatory Hyperalgesia in Rats Following Carrageenan Injection
    Yanan Zhang, Chunlian Zhang, Haiou Li, Jingdong Hou · 2019 · Inflammation
48. Transmethylamine‐N‐Oxide Is Associated With Diffuse Cardiac Fibrosis in People Living With HIV
    Nalini Colaco, Teresa S. Wang, Yifei Ma, Rebecca Scherzer, Olga Ilkayeva, Patrice M. Desvigne-Nickens, Eugene Braunwald, Adrian F. Hernandez, Javed Butler, Svati Hasmukh Shah et al. · 2021 · Journal of the American Heart Association
49. Monosodium glutamate consumption reduces the renal excretion of trimethylamine N-oxide and the abundance of Akkermansia muciniphila in the gut
    Thin Su Kyaw, Manatsaphon Sukmak, Kanokwan Nahok, Amod Sharma, Atit Silsirivanit, Worachart Lert-itthiporn, Nichapa Sansurin, Vichai Senthong, Sirirat Anutrakulchai, Sakkarn Sangkhamanon et al. · 2022 · Biochemical and Biophysical Research Communications
50. Diet-induced chronic syndrome, metabolically transformed trimethylamine-N-oxide, and the cardiovascular functions
    Shanna J. Hardin, Mahavir Singh, Wintana Eyob, Jack Molnar, Rubens P. Homme, Akash K. George, Suresh C. Tyagi · 2019 · Reviews in Cardiovascular Medicine
51. Related factors based on non-targeted metabolomics methods in minor ischaemic stroke
    Chen Chen, Xiaoyuan Qiao, Jianyong Guo, Ting Yang, Min Wang, Yipeng Ma, Shuhe Zhao, Ling Ding, Hong Liu, Jintao Wang · 2022 · Frontiers in Endocrinology
52. Gut-heart axis: cardiac remodeling and heart failure in the context of inflammatory bowel disease and dysbiosis
    THIERRY KOCHKARIAN, Hania I. Nagy, Qingjie Li · 2025 · American Journal of Physiology-Gastrointestinal and Liver Physiology
53. The Interplay of Microbiome Dysbiosis and Cardiovascular Disease
    Anas Zaher, Jude ElSaygh, Stephen J. Peterson, Ilan S. Weisberg, Manish A. Parikh, William H. Frishman · 2024 · Cardiology in Review
54. Circulating TMAO, the gut microbiome and cardiometabolic disease risk: an exploration in key precursor disorders
    Saba Naghipour, Amanda J. Cox, Joshua J. Fisher, Manuel R. Plan, Terra Stark, Nicholas P. West, Jason N. Peart, John Patrick Headrick, Eugene F. Du Toit · 2024 · Diabetology & Metabolic Syndrome
55. Effects of choline metabolite—trimethylamine N-oxide on immunometabolism in inflammatory bowel disease
    Siyu Wang, Yifan Ni, Shuwei Zhou, Huiping Peng, Ying Cao, Yue Zhu, Jing Gong, Qiulu Lu, Zhongyu Han, Yumeng Lin et al. · 2025 · Frontiers in Immunology
56. Circulating microbiota and metabolites: Insights into cardiovascular diseases
    Ikram Khan, Imran Khan, Muhammad Usman, Zhang Xiao Wei, Xie Ping, Sarmir Khan, Feroz Khan, Zhou Jianye, Li Zhiqiang, Lizhe An · 2022 · Journal of Clinical Laboratory Analysis
57. A disturbed communication between hypothalamic-pituitary-ovary axis and gut microbiota in female infertility: is diet to blame?
    Fatima Ahmad, Salma Hayder Ahmed, Fadi Choucair, Spyridon Chouliaras, Johnny T. Awwad, Annalisa Terranegra · 2025 · Journal of Translational Medicine
58. A bacterial metabolite, trimethylamine N-oxide, disrupts the hemostasis balance in human primary endothelial cells but no coagulopathy in mice
    Saravanan Subramaniam, Sarra Boukhlouf, Craig Fletcher · 2019 · Blood Coagulation & Fibrinolysis
59. Independent Predictors of Circulating Trimethylamine N-Oxide (TMAO) and Resistin Levels in Subjects with Obesity: Associations with Carotid Intima-Media Thickness and Metabolic Parameters
    Denisa Pescari, Monica Simina Mihuţa, Andreea Bena, Dana Stoian · 2025 · Nutrients
60. Composition of gut microbiota and its correlations with neurological, intestinal, cardiovascular and metabolic diseases
    Morena Sciuto, Roberto Catanzaro · 2023 · Acta Microbiologica et Immunologica Hungarica
61. Heart Failure and Gut Microbiota: What Is Cause and Effect?
    Shichun Shen, Beiduo Tian, Zhang Haizhu, Yuchen Wang, Tao Li, Yang Cao · 2025 · Research
62. Repeated 3,3-Dimethyl-1-butanol exposure alters social dominance in adult mice
    Jiawen Mao, Penghui Zhao, Qian Wang, Aixin Chen, Xuzi Li, Xianjie Li, Tingxuan Liu, Zifei Tao, Xi Wang, Yuru Du et al. · 2021 · Neuroscience Letters
63. Gut–Kidney–Heart: A Novel Trilogy
    Mario Caldarelli, Laura Franza, Pierluigi Rio, Antonio Gasbarrini, Giovanni Gambassi, Rossella Cianci · 2023 · Biomedicines
64. Intestinal Microbiota and Derived Metabolites in Myocardial Fibrosis and Postoperative Atrial Fibrillation
    Antonio Nenna, Alice Laudisio, Chiara Taffon, Marta Fogolari, Cristiano Spadaccio, Chiara Ferrisi, Francesco Loreni, Omar Giacinto, Ciro Mastroianni, Raffaele Barbato et al. · 2024 · International Journal of Molecular Sciences
65. Microbial Metabolites and Cardiovascular Dysfunction: A New Era of Diagnostics and Therapy
    Jitendra Kumar · 2025 · Cells
66. Adipose tissue: an inflammatory organ that can not be ignored in periodontal disease related to obesity
    Qiqi Wang, Hongyan Li, Huan Yu, Tianyu Zhou, Jingdan Zhang, Rongkaixuan Fang, Yue Sun, Lan A, Wenzhou Xu · 2025 · Frontiers in Immunology
67. Trimethylamine N-Oxide as a Potential Risk Factor for Non-communicable Diseases: A Systematic Review
    Zahra Hoseini Tavassol, Hanieh‐Sadat Ejtahed, Bagher A. Larijani, Shirin Hasani‐Ranjbar · 2022 · Endocrine Metabolic & Immune Disorders - Drug Targets
68. Role of Gut Microbiome in Atherosclerosis: Molecular and Therapeutic Aspects
    Juan Salazar, Valery Morillo, M Suarez, Ana Valéria Castro, Paola Ramírez, Milagros Rojas, Roberto Áñez, Luis D’Marco, Maricarmen Chacín, Valmore Bermúdez · 2023 · Current Cardiology Reviews
69. Systemic investigation of di-isobutyl phthalate (DIBP) exposure in the risk of cardiovascular via influencing the gut microbiota arachidonic acid metabolism in obese mice model
    Min Liu, Xifeng Du, Huifang Chen, Chenkai Bai, Lizhen Lan · 2024 · Regenerative Therapy
70. Mechanistic Review on the Role of Gut Microbiota in the Pathology of Cardiovascular Diseases
    Iqra Usman, Aamir Anwar, Shivang Shukla, Priya Pathak · 2024 · Cardiovascular & Haematological Disorders - Drug Targets
71. Interventions for non-alcoholic liver disease: a gut microbial metabolites perspective
    Jin Guo, Chunxia Shi, Qingqi Zhang, Wei Deng, Luyi Zhang, Qian Chen, Danmei Zhang, Zuojiong Gong · 2022 · Therapeutic Advances in Gastroenterology
72. Cardiovascular Diseases and Pharmacomicrobiomics: A Perspective on Possible Treatment Relevance
    Lavinia Curini, Amedeo Amedei · 2021 · Biomedicines
73. Trimethylamine-N-Oxide (TMAO) and Predicted Risk of Cardiovascular Events After Partial Nephrectomy
    Xiangpeng Zou, Longbin Xiong, Zhixing Guo, Yuchen Li, Ning Kang, Xiaohua Liu, Ye Xie, Yulu Peng, Yixuan Liu, Xinyang Cai et al. · 2022 · Asian Journal of Surgery
74. The gut microbiota-inflammation-HFpEF axis: deciphering the role of gut microbiota dysregulation in the pathogenesis and management of HFpEF
    Shenghua Zhou, Xuan Zhou, Panpan Zhang, Wei Zhang, Jinli Huang, Xuzhao Jia, Xiaole He, Xin Sun, Hui Su · 2025 · Frontiers in Cellular and Infection Microbiology
75. Gut Microbiota Composition and Metabolites as the new Determinants of Cardiovascular Pathology Development
    Oksana M. Drapkina, A. N. Kaburova · 2020 · Rational Pharmacotherapy in Cardiology
76. Can manipulation of gut microbiota really be transformed into an intervention strategy for cardiovascular disease management?
    Khalid Mehmood, Afrasim Moin, Talib Hussain, Syed Mohd Danish Rizvi, DV Gowda, Shazi Shakil, MA Kamal · 2021 · Folia Microbiologica
77. Serum lysophospholipidome of dietary origin as a suitable susceptibility/risk biomarker of human hypercholesterolemia: A cross-sectional study
    Lorena Calderón-Pérez, Susana Suárez‐Garcia, Anna Pedret, Manuel Suárez, Elisabet Llauradó, Laura Rubió, Josep M Del Bas-Prior, Antoni Caimari, Francesc Puiggròs, Lluı́s Arola et al. · 2021 · Clinical Nutrition
78. Impact of Diet on Gut Microbiota Composition and Microbiota-Associated Functions in Heart Failure: A Systematic Review of In Vivo Animal Studies
    Marta Palombaro, Pauline Celine Raoul, Marco Cintoni, Emanuele Rinninella, Gabriele Pulcini, Nadia Aspromonte, Gianluca Ianiro, Antonio Gasbarrini, Maria Cristina Mele · 2022 · Metabolites
79. A gut microbiome metabolite paradoxically depresses contractile function while activating mitochondrial respiration
    Saba Naghipour, Joshua J. Fisher, Anthony V. Perkins, Jason N. Peart, John Patrick Headrick, Eugene F. Du Toit · 2023 · Disease Models & Mechanisms
80. Association between systemic immune-inflammation index and trimethylamine N-oxide levels in peripheral blood and osteoporosis in overweight and obese patients
    Lingling Li, Jinyang An, Jia Bai, Yangyang Zhang, Xinsai Li, Haihong Lv · 2025 · Frontiers in Endocrinology
81. The role of trimethylamine N-oxide in disease pathogenesis and the therapeutic potential of traditional Chinese medicine
    Zizhen Qin, Wanning Wu, Xinyu Yang, Xiao Wang, Anni Ding, Yueyi Huang, Jiaxuan Tang, Siyuan Jiang, Peng Zhang, Chenwei Qian et al. · 2025 · Frontiers in Pharmacology
82. Gut Molecules in Cardiometabolic Diseases: The Mechanisms behind the Story
    Andreea-Ioana Inceu, Maria Adriana Neag, Anca Elena Craciun, Anca Dana Buzoianu · 2023 · International Journal of Molecular Sciences
83. Trimethylamine N-oxide generation process was influenced by the proportion and source of macronutrients in the diet
    Chengcheng Wang, Xuefeng Duan, Xiaoyue Li, Jin‐Yue Yang, Changhu Xue, Teruyoshi Yanagita, Tiantian Zhang, Yuming Wang · 2023 · Food Science and Human Wellness
84. Analyzing the Complicated Connection Between Intestinal Microbiota and Cardiovascular Diseases
    Tanishq Kumar, Rajoshee R Dutta, Vivek R Velagala, Benumadhab Ghosh, Abhay Bhausaheb Mudey · 2022 · Cureus
85. The Relationship between Atherosclerosis and Gut Microbiome in Patients with Obstructive Sleep Apnoea
    Helga Szabó, Márton Piroska, Anita Hernyes, Luca Zoldi, János Juhász, Balázs Ligeti, Nóra Makra, Dóra Szabó, András Bikov, László Kunos et al. · 2022 · Applied Sciences
86. Unlocking Cardioprotective Potential of Gut Microbiome: Exploring Therapeutic Strategies
    Jun Qu, Fantao Meng, Zhen Wang, Wenhao Xu · 2024 · Journal of Microbiology and Biotechnology
87. Gut Microbiota and Short-Chain Fatty Acids in Cardiometabolic HFpEF: Mechanistic Pathways and Nutritional Therapeutic Perspectives
    Antonio Vacca, Gabriele Brosolo, Stefano Marcante, Sabrina Della Mora, Luca Bulfone, A. Da Porto, Claudio Pagano, Cristiana Catena, Leonardo Alberto Sechi · 2026 · Nutrients
88. The Gut Axis Involvement in Heart Failure
    Andrea Salzano, Shabana Cassambai, Y Yazaki, Muhammad Zubair Israr, Dennis Bernieh, Max Wong, Toru Suzuki · 2022 · Cardiology Clinics
89. Diet, inflammation, and cardiovascular disease
    Farhad Vahid, David E. Chiriboga, Torsten Bohn, James R. Hébert · 2022 · Elsevier eBooks
90. Association between Intestinal Microecological Changes and Atherothrombosis
    Xinyu Zhuo, Hui Luo, Rumei Lei, Xiaokun Lou, Jing Bian, Junfeng Guo, Hao Luo, Xingwei Zhang, Qibin Jiao, Wenyan Gong · 2023 · Microorganisms
91. Trimethylamine N-oxide induces cardiac diastolic dysfunction by down-regulating Piezo1 in mice with heart failure with preserved ejection fraction
    Qian Chen, Huaxing Zhang, Yuhong Chen, Yei‐Mei Peng, Yuhan Yao, Hongmei Xue, Qi Guo, Danyang Tian, Lin Xiao, Xu Teng et al. · 2025 · Life Sciences
92. TMAO and the gut microbiome: implications for the CVD-CKD-IBD axis
    Si Hyoung Kim, Mi Young Yoon, Sang Sun Yoon · 2025 · Annals of Medicine
93. From Gut to Heart: Targeting Trimethylamine N-Oxide as a Novel Strategy in Heart Failure Management
    Zehui Ding, Yunfeng Yu, Jiaming Wei, Ziyan Wang, Ruifang Lin, Ya Li, Zhihua Guo · 2025 · Biomolecules
94. Dietary Fatty Acids Modulate Gut Microbiota-Derived Trimethylamine-N-Oxide: Potential Mechanisms and Future Perspective
    Ece Kilic, Pervin Başaran · 2025 · Nutrients
95. The Interplay between Cardiovascular Disease, Exercise, and the Gut Microbiome
    Candace R. Longoria, John J. Guers, Sara C. Campbell · 2022 · Reviews in Cardiovascular Medicine
96. Evaluation of the Feasibility of In Vitro Metabolic Interruption of Trimethylamine with Resveratrol Butyrate Esters and Its Purified Monomers
    Ping‐Hsiu Huang, Dequan Chen, Yu‐Wei Chen, Ming‐Kuei Shih, Bao‐Hong Lee, You‐Lin Tain, Chang‐Wei Hsieh, Chih‐Yao Hou · 2024 · Molecules
97. The Role of Gut Microbiota and Associated Compounds in Cardiovascular Health and its Therapeutic Implications
    Lu Liu, Guneet Inder Jit Kaur, Avinash Kumar, Abhinav Kanwal, Shailendra Pratap Singh · 2024 · Cardiovascular & Hematological Agents in Medicinal Chemistry
98. Impact of Hypoxia–Hyperoxia Exposures on Cardiometabolic Risk Factors and TMAO Levels in Patients with Metabolic Syndrome
    Afina Bestavashvili, Oleg Stanislavovich Glazachev, Shabnam I. Ibragimova, А. Yu. Suvorov, Alexandros Bestavasvili, Shevket Girey Ibraimov, Xinliang Zhang, Yong Zhang, Chavdar S Pavlov, Е. А. Сыркина et al. · 2023 · International Journal of Molecular Sciences
99. 3,3-Dimethyl-1-Butanol and its Metabolite 3,3-Dimethylbutyrate Ameliorate Collagen-induced Arthritis Independent of Choline Trimethylamine Lyase Activity
    Sabrina Fechtner, Brendan E. Allen, Meagan E. Chriswell, Widian K. Jubair, Charles E. Robertson, Jennifer M. Kofonow, Daniel N. Frank, Vernon Michael Holers, Kristine A. Kuhn · 2024 · Inflammation
100. The Prevention of Inflammation and the Maintenance of Iron and Hepcidin Homeostasis in the Gut, Liver, and Brain Pathologies
     Barbara Kania, Alexis Sotelo, Darren Ty, Jonathan J. Wisco · 2023 · Journal of Alzheimer s Disease