A cross-sectional study of smoking and depression among US adults: NHANES (2005–2018)
Abstract
Background: The relationship between smoking and depression remains controversial. This study aimed to investigate the association between smoking and depression from three aspects: smoking status, smoking volume, and smoking cessation. Methods: Data from adults aged ≥20 who participated in the National Health and Nutrition Examination Survey (NHANES) between 2005 and 2018 were collected. The study gathered information about the participants' smoking status (never smokers, previous smokers, occasional smokers, daily smokers), smoking quantity per day, and smoking cessation. Depressive symptoms were assessed using the Patient Health Questionnaire (PHQ-9), with a score ≥10 indicating the presence of clinically relevant symptoms. Multivariable logistic regression was conducted to evaluate the association of smoking status, daily smoking volume, and smoking cessation duration with depression. Results: Previous smokers [odds ratio (OR) = 1.25, 95% confidence interval (CI): 1.05–1.48] and occasional smokers (OR = 1.84, 95% CI: 1.39–2.45) were associated with a higher risk of depression compared with never smokers. Daily smokers had the highest risk of depression (OR = 2.37, 95% CI: 2.05–2.75). In addition, a tendency toward a positive correlation was observed between daily smoking volume and depression (OR = 1.65, 95% CI: 1.24–2.19) ( P for trend < 0.05). Furthermore, the longer the smoking cessation duration, the lower the risk of depression (OR = 0.55, 95% CI: 0.39–0.79) ( P for trend < 0.05). Conclusions: Smoking is a behavior that increases the risk of depression. The higher the smoking frequency and smoking volume, the higher the risk of depression, whereas smoking cessation is associated with decreased risk of depression, and the longer the smoking cessation duration, the lower the risk of depression.
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A cross-sectional study among 30,524 US adults from NHANES revealed that individuals who currently or previously smoked have a heightened risk of experiencing depression compared to those who have never smoked.
“a cross-sectional study conducted among a sample of 30,524 US adults from the National Health and Nutrition Examination Survey (NHANES) revealed that individuals who currently or previously smoked have a heightened risk of experiencing depression compared to those who have never smoked [11].”
From Associations between smoking, sex steroid hormones, trouble sleeping, and depression among U.S. adults: a cross-sectional study from NHANES (2013–2016) (2024) · cites this paper as [11]
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Cites
Kroenke, K., Spitzer, R. L., Williams, J. B. W., & Löwe, B. (2010) · General Hospital Psychiatry · doi:10.1016/j.genhosppsych.2010.03.006 · Cited by 4,057 · see citing works
Wang, X., & Cheng, Z. (2020) · CHEST · doi:10.1016/j.chest.2020.03.012 · Cited by 2,214 · see citing works
Psychological Treatment of Depression in Primary Care: Recent Developments
Cuijpers, P., Quero, S., Dowrick, C., & Arroll, B. (2019) · Current Psychiatry Reports · doi:10.1007/s11920-019-1117-x · Cited by 296 · see citing works
Sheals, K., Tombor, I., McNeill, A., & Shahab, L. (2016) · Addiction · doi:10.1111/add.13387 · Cited by 204 · cited 2× · see citing works
“Unlike their counterparts in other countries, mental health professionals in the US do not consider the adverse effects of smoking cessation (7).”
BackgroundAnstey, K. J., von Sanden, C., Sargent-Cox, K., & Luszcz, M. A. (2007) · The American Journal of Geriatric Psychiatry · doi:10.1097/jgp.0b013e31802e21d8 · Cited by 192 · see citing works
Flagged first, then by citations
Research works printed but not linked: 26
- [1]Wootton RE Richmond RC Stuijfzand BG Lawn RB Sallis HM Taylor GMJ. Evidence for causal effects of lifetime smoking on risk for depression and schizophrenia: a Mendelian randomisation study. Psychol Med. (2020) 50: 2435– 43. 10.1017/S0033291719002678 31689377 PMC7610182 · DOI · Paper page
- [2]Weinberger AH Kashan RS Shpigel DM Esan H Taha F Lee CJ. Depression and cigarette smoking behavior: a critical review of population-based studies. Am J Drug Alcohol Abuse. (2017) 43: 416– 31. 10.3109/00952990.2016.1171327 27286288 · DOI · Paper page
- [5]Park LT Zarate CA Jr. Depression in the primary care setting. N Engl J Med. (2019) 380: 559– 68. 10.1056/NEJMcp1712493 30726688 PMC6727965 · DOI
- [6]Taylor GMJ Munafo MR. What about treatment of smoking to improve survival and reduce depression? Lancet Psychiatry. (2018) 5: 464. 10.1016/S2215-0366(18)30132-9 29857836 · DOI
- [8]Munafo MR Hitsman B Rende R Metcalfe C Niaura R. Effects of progression to cigarette smoking on depressed mood in adolescents: evidence from the National Longitudinal Study of Adolescent Health. Addiction. (2008) 103: 162– 71. 10.1111/j.1360-0443.2007.02052.x 18031565 · DOI
- [9]Taylor G Girling A McNeill A Aveyard P. Does smoking cessation result in improved mental health? A comparison of regression modelling and propensity score matching. BMJ Open. (2015) 5: e008774. 10.1136/bmjopen-2015-008774 26490099 PMC4620166 · DOI
- [10]Cavazos-Rehg PA Breslau N Hatsukami D Krauss MJ Spitznagel EL Grucza RA. Smoking cessation is associated with lower rates of mood/anxiety and alcohol use disorders. Psychol Med. (2014) 44: 2523– 35. 10.1017/S0033291713003206 25055171 PMC4122254 · DOI
- [11]Liu S Jiang H Zhang D Luo J Zhang H. The association between smoking cessation and depressive symptoms: diet quality plays a mediating role. Nutrients. (2022) 14: 3047. 10.3390/nu14153047 35893901 PMC9331914 · DOI
- [12]Paulose-Ram R Graber JE Woodwell D Ahluwalia N. The National Health and Nutrition Examination Survey (NHANES), 2021–2022: adapting data collection in a COVID-19 environment. Am J Public Health. (2021) 111: 2149– 56. 10.2105/AJPH.2021.306517 34878854 PMC8667826 · DOI
- [13]Lei J Luo Y Xie Y Wang X. Visceral adiposity index is a measure of the likelihood of developing depression among adults in the United States. Front Psychol. (2022) 13: 772556. 10.3389/fpsyg.2022.772556 35401344 PMC8991090 · DOI
- [14]Fan JX Wen M Li K. Associations between obesity and neighborhood socioeconomic status: variations by gender and family income status. SSM Popul Health. (2020) 10: 100529. 10.1016/j.ssmph.2019.100529 31890849 PMC6928347 · DOI
- [15]Park S Lee KS. Association of heated tobacco product use and secondhand smoke exposure with suicidal ideation, suicide plans and suicide attempts among Korean adolescents: a 2019 national survey. Tob Induc Dis. (2021) 19: 72. 10.18332/tid/140824 34602935 PMC8448199 · DOI
- [16]Frerichs RR Aneshensel CS Clark VA Yokopenic P. Smoking and depression: a community survey. Am J Public Health. (1981) 71: 637– 40. 10.2105/AJPH.71.6.637 7235104 PMC1619820 · DOI
- [17]Mino Y Shigemi J Otsu T Ohta A Tsuda T Yasuda N. Smoking and mental health: cross-sectional and cohort studies in an occupational setting in Japan. Prev Med. (2001) 32: 371– 5. 10.1006/pmed.2000.0803 11304098 · DOI
- [19]Li Y Zhang C Ding S Li J Li L Kang Y. Physical activity, smoking, alcohol consumption and depressive symptoms among young, early mature and late mature people: a cross-sectional study of 76,223 in China. J Affect Disord. (2022) 299: 60– 6. 10.1016/j.jad.2021.11.054 34822919 · DOI
- [20]Fluharty M Taylor AE Grabski M Munafo MR. The association of cigarette smoking with depression and anxiety: a systematic review. Nicotine Tob Res. (2017) 19: 3– 13. 10.1093/ntr/ntw140 27199385 PMC5157710 · DOI · Paper page
- [21]Khaled SM Bulloch AG Williams JV Hill JC Lavorato DH Patten SB. Persistent heavy smoking as risk factor for major depression (MD) incidence–evidence from a longitudinal Canadian cohort of the National Population Health Survey. J Psychiatr Res. (2012) 46: 436– 43. 10.1016/j.jpsychires.2011.11.011 22277304 · DOI
- [22]Markou A Kosten TR Koob GF. Neurobiological similarities in depression and drug dependence: a self-medication hypothesis. Neuropsychopharmacology. (1998) 18: 135– 74. 10.1016/S0893-133X(97)00113-9 9471114 · DOI · Paper page
- [23]Secades-Villa R Weidberg S Gonzalez-Roz A Reed DD Fernandez-Hermida JR. Cigarette demand among smokers with elevated depressive symptoms: an experimental comparison with low depressive symptoms. Psychopharmacology. (2018) 235: 719– 28. 10.1007/s00213-017-4788-1 29143193 · DOI
- [24]Haustein KO Haffner S Woodcock BG. A review of the pharmacological and psychopharmacological aspects of smoking and smoking cessation in psychiatric patients. Int J Clin Pharmacol Ther. (2002) 40: 404– 18. 10.5414/CPP40404 12358157 · DOI
- [25]Picciotto MR Brunzell DH Caldarone BJ. Effect of nicotine and nicotinic receptors on anxiety and depression. Neuroreport. (2002) 13: 1097– 106. 10.1097/00001756-200207020-00006 12151749 · DOI · Paper page
- [26]Thrul J Gubner NR Tice CL Lisha NE Ling PM. Young adults report increased pleasure from using e-cigarettes and smoking tobacco cigarettes when drinking alcohol. Addict Behav. (2019) 93: 135– 40. 10.1016/j.addbeh.2019.01.011 30710807 PMC6503655 · DOI
- [27]Piirtola M Kaprio J Baker TB Piasecki TM Piper ME Korhonen T. The associations of smoking dependence motives with depression among daily smokers. Addiction. (2021) 116: 2162– 74. 10.1111/add.15390 33629475 PMC8274496 · DOI
- [28]Copeland AL Kulesza M Hecht GS. Pre-quit depression level and smoking expectancies for mood management predict the nature of smoking withdrawal symptoms in college women smokers. Addict Behav. (2009) 34: 481– 3. 10.1016/j.addbeh.2008.12.007 19157715 · DOI
- [29]Shahab L West R. Do ex-smokers report feeling happier following cessation? Evidence from a cross-sectional survey. Nicotine Tob Res. (2009) 11: 553– 7. 10.1093/ntr/ntp031 19351779 · DOI
- [30]Dos Santos VA Migott AM Bau CH Chatkin JM. Tobacco smoking and depression: results of a cross-sectional study. Br J Psychiatry. (2010) 197: 413– 4. 10.1192/bjp.197.5.413 21037220 · DOI
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Huang, J., Shi, P., Zhao, Y., Zhang, H., Gao, T., & Wang, X. (2024) · BMC Public Health · doi:10.1186/s12889-024-19045-0 · Cited by 13 · see citing works
- Authors
- Wu, Z., Yue, Q., Zhao, Z., Wen, J., Tang, L., Zhong, Z., Yang, J., Yuan, Y., & Zhang, X.
- Venue
- Frontiers in Public Health
- Publisher
- Frontiers Media SA
- Published
- 2023-01-30
- Volume
- 11
- ISSN
- 2296-2565
- PMC
- PMC9922891
- Cited by
- 109
- References
- 5
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