Melatonin and Related Compounds: Antioxidant and Anti-Inflammatory Actions

Melatonin as an antioxidant: under promises but over delivers

Reiter, R. J., Mayo, J. C., Tan, D. X., Sainz, R. M., Alatorre-Jiménez, M. A., & Qin, L. (2016) · Journal of Pineal Research · doi:10.1111/jpi.12360 · Cited by 1,741 · see citing works

Pulmonary arterial hypertension: pathogenesis and clinical management

Thenappan, T., Ormiston, M. L., Ryan, J. J., & Archer, S. L. (2018) · BMJ · doi:10.1136/bmj.j5492 · Cited by 1,004 · see citing works

Formation of starch in plant cells

Pfister, B., & Zeeman, S. C. (2016) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-016-2250-x · Cited by 422 · see citing works

Is Melatonin the Cornucopia of the 21st Century?

Ferlazzo, N., Andolina, G., Cannata, A., Costanzo, M. G., Rizzo, V., Currò, M., Ientile, R., & Caccamo, D. (2020) · Antioxidants · doi:10.3390/antiox9111088 · Cited by 189 · see citing works

Function of Chloroplasts in Plant Stress Responses

Song, Y., Feng, L., Alyafei, M. A. M., et al. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms222413464 · Cited by 155 · see citing works

Melatonin potentials against viral infections including COVID-19: Current evidence and new findings

Juybari, K. B., Pourhanifeh, M. H., Hosseinzadeh, A., Hemati, K., & Mehrzadi, S. (2020) · Virus Research · doi:10.1016/j.virusres.2020.198108 · Cited by 129 · see citing works

Endothelial Dysfunction, Inflammation, and Oxidative Stress in COVID‐19—Mechanisms and Therapeutic Targets

Fodor, A., Tiperciuc, B., Login, C., Orasan, O. H., Lazăr, A.-L., Buchman, C., Hanghicel, P., Sitar-Tăut, A., Suharoschi, R., Vulturar, R., et al. (2021) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2021/8671713 · Cited by 123 · see citing works

Impact of Melatonin on Skeletal Muscle and Exercise

Stacchiotti, A., Favero, G., & Rodella, L. F. (2020) · Cells · doi:10.3390/cells9020288 · Cited by 115 · see citing works

SARS-CoV-2 infection and oxidative stress: Pathophysiological insight into thrombosis and therapeutic opportunities

Alam, M. S., & Czajkowsky, D. M. (2021) · Cytokine & Growth Factor Reviews · doi:10.1016/j.cytogfr.2021.11.001 · Cited by 101 · see citing works

Efficacy of a Low Dose of Melatonin as an Adjunctive Therapy in Hospitalized Patients with COVID-19: A Randomized, Double-blind Clinical Trial

Farnoosh, G., Akbariqomi, M., Badri, T., et al. (2021) · Archives of Medical Research · doi:10.1016/j.arcmed.2021.06.006 · Cited by 94 · see citing works

Role and Therapeutic Potential of Melatonin in Various Type of Cancers

Gurunathan, S., Qasim, M. H., Kang, M.-H., & Kim, J. (2021) · OncoTargets and Therapy · doi:10.2147/ott.s298512 · Cited by 92 · see citing works

The Effect of Melatonin on Thrombosis, Sepsis and Mortality Rate in COVID-19 Patients

Hasan, Z. T., Al-Atrakji, M. Q. Y. M. A., & Mehuaiden, A. K. (2021) · International Journal of Infectious Diseases · doi:10.1016/j.ijid.2021.10.012 · Cited by 90 · see citing works

Can Melatonin Be a Potential “Silver Bullet” in Treating COVID-19 Patients?

Cardinali, D. P., Brown, G. M., & Pandi-Perumal, S. R. (2020) · Diseases · doi:10.3390/diseases8040044 · Cited by 82 · see citing works

Melatonin effects on sleep quality and outcomes of COVID‐19 patients: An open‐label, randomized, controlled trial

Mousavi, S. A., Heydari, K., Mehravaran, H., Saeedi, M., Alizadeh‐Navaei, R., Hedayatizadeh‐Omran, A., & Shamshirian, A. (2021) · Journal of Medical Virology · doi:10.1002/jmv.27312 · Cited by 81 · see citing works

Human hepatocellular carcinoma: Protection by melatonin

Mortezaee, K. (2018) · Journal of Cellular Physiology · doi:10.1002/jcp.26586 · Cited by 72 · see citing works

The Role of Melatonin on NLRP3 Inflammasome Activation in Diseases

Arioz, B. I., Tarakcioglu, E., Olcum, M., & Genç, Ş. (2021) · Antioxidants · doi:10.3390/antiox10071020 · Cited by 67 · see citing works

Melatonin Ameliorates Inflammation and Oxidative Stress by Suppressing the p38MAPK Signaling Pathway in LPS-Induced Sheep Orchitis

Deng, S.-L., Zhang, B.-L., Reiter, R. J., & Liu, Y.-X. (2020) · Antioxidants · doi:10.3390/antiox9121277 · Cited by 59 · see citing works

Melatonin as an Antitumor Agent against Liver Cancer: An Updated Systematic Review

Fernández‐Palanca, P., Méndez‐Blanco, C., Fondevila, F., Tuñón, M. J., Reiter, R. J., Mauriz, J. L., & González‐Gallego, J. (2021) · Antioxidants · doi:10.3390/antiox10010103 · Cited by 51 · see citing works

Melatonin possesses an anti-influenza potential through its immune modulatory effect

Huang, S., Liao, C., Chen, S., Shi, L.-G., Lin, L., Chen, Y.-W., Cheng, C.-P., Sytwu, H., Shang, S.-T., & Lin, G. (2019) · Journal of Functional Foods · doi:10.1016/j.jff.2019.04.062 · Cited by 50 · see citing works

Melatonin and pancreatic cancer: Current knowledge and future perspectives

Tamtaji, O. R., Mirhosseini, N. Z., Reiter, R. J., Behnamfar, M., & Asemi, Z. (2018) · Journal of Cellular Physiology · doi:10.1002/jcp.27372 · Cited by 49 · see citing works

Melatonin as a Potential Adjuvant Treatment for COVID-19 beyond Sleep Disorders

Wichniak, A., Kania, A., Siemiński, M., & Cubała, W. J. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22168623 · Cited by 48 · see citing works

Melatonin alleviates LPS‐induced endoplasmic reticulum stress and inflammation in spermatogonial stem cells

Yang, D., Wei, Y., Lu, Q., Qin, D., Zhang, M., Du, X., Xu, W., Yu, X., He, C., Li, N., et al. (2020) · Journal of Cellular Physiology · doi:10.1002/jcp.30088 · Cited by 46 · see citing works

Melatonin Regulates Chloroplast Protein Quality Control via a Mitogen-Activated Protein Kinase Signaling Pathway

Lee, H. Y., & Back, K. (2021) · Antioxidants · doi:10.3390/antiox10040511 · Cited by 44 · see citing works

Melatonin Reduces NLRP3 Inflammasome Activation by Increasing α7 nAChR-Mediated Autophagic Flux

Farré‐Alins, V., Narros‐Fernández, P., Palomino‐Antolín, A., Decouty‐Pérez, C., López-Rodríguez, A. B., Parada, E., Muñoz-Montero, A., Gómez‐Rangel, V., Lopez-Munoz, F. J., Ramos, E., et al. (2020) · Antioxidants · doi:10.3390/antiox9121299 · Cited by 43 · see citing works

Melatonin interferes with COVID-19 at several distinct ROS-related steps

Camp, O. G., Bai, D., Gonullu, D. C., Nayak, N., & Abu‐Soud, H. M. (2021) · Journal of Inorganic Biochemistry · doi:10.1016/j.jinorgbio.2021.111546 · Cited by 43 · see citing works

Melatonin Targets Metabolism in Head and Neck Cancer Cells by Regulating Mitochondrial Structure and Function

Guerra‐Librero, A., Fernández-Gil, B. I., Florido, J., Martínez-Ruiz, L., Rodríguez-Santana, C., Shen, Y., García‐Verdugo, J. M., López‐Rodríguez, A., Rusanova, I., Quiñones‐Hinojosa, A., et al. (2021) · Antioxidants · doi:10.3390/antiox10040603 · Cited by 39 · see citing works

A Pilot Study on Controlling Coronavirus Disease 2019 (COVID-19) Inflammation Using Melatonin Supplement

Alizadeh, Z., Keyhanian, N., Ghaderkhani, S., Dashti‐Khavidaki, S., Shoormasti, R. S., & Pourpak, Z. (2021) · Iranian Journal of Allergy Asthma and Immunology · doi:10.18502/ijaai.v20i4.6959 · Cited by 36 · see citing works

Role of Melatonin on Virus-Induced Neuropathogenesis—A Concomitant Therapeutic Strategy to Understand SARS-CoV-2 Infection

Wongchitrat, P., Shukla, M., Sharma, R., Govitrapong, P., & Reiter, R. J. (2021) · Antioxidants · doi:10.3390/antiox10010047 · Cited by 35 · see citing works

Mechanisms and clinical evidence to support melatonin's use in severe COVID-19 patients to lower mortality

Tan, D. X., & Reiter, R. J. (2022) · Life Sciences · doi:10.1016/j.lfs.2022.120368 · Cited by 32 · see citing works

The Coronavirus Disease 2019 (COVID-19): Key Emphasis on Melatonin Safety and Therapeutic Efficacy

Ramos, E., Lopez-Munoz, F. J., Gil‐Martín, E., Egea, J., Álvarez‐Merz, I., Painuli, S., Semwal, P., Martins, N. A., Hernández-Guijo, J. M., & Romero, A. (2021) · Antioxidants · doi:10.3390/antiox10071152 · Cited by 25 · see citing works

The Impact of Melatonin and NLRP3 Inflammasome on the Expression of microRNAs in Aged Muscle

Sayed, R. K. A., Fernández‐Ortiz, M., Fernández‐Martínez, J., Aranda‐Martínez, P., Guerra‐Librero, A., Rodríguez-Santana, C., de Haro, T., Escames, G., Acuña-Castroviejo, D., & Rusanova, I. (2021) · Antioxidants · doi:10.3390/antiox10040524 · Cited by 23 · see citing works

Melatonin Reduces Oxidative Stress in the Right Ventricle of Newborn Sheep Gestated under Chronic Hypoxia

González‐Candia, A., Arias, P. V., Aguilar, S. A., et al. (2021) · Antioxidants · doi:10.3390/antiox10111658 · Cited by 21 · see citing works

Protective effects of melatonin on the white matter damage of neonatal rats by regulating NLRP3 inflammasome activity

Qin, M., Liu, Y., Sun, M., Li, X., Xu, J., Zhang, L., & Jiang, H. F. (2021) · Neuroreport · doi:10.1097/wnr.0000000000001642 · Cited by 18 · see citing works

Beneficial effects of melatonin on prostanoids pathways in pulmonary hypertensive neonates

Figueroa, E. G., González‐Candia, A., Villanueva, C. A., Ebensperger, G., Reyes, R. V., Llanos, A. J., & Herrera, E. A. (2021) · Vascular Pharmacology · doi:10.1016/j.vph.2021.106853 · Cited by 16 · see citing works

Usefulness of Melatonin and Other Compounds as Antioxidants and Epidrugs in the Treatment of Head and Neck Cancer

Guerra, J., & Devesa, J. (2021) · Antioxidants · doi:10.3390/antiox11010035 · Cited by 14 · see citing works

Melatonin Modulates the Antioxidant Defenses and the Expression of Proinflammatory Mediators in Pancreatic Stellate Cells Subjected to Hypoxia

Estarás, M., González-Portillo, M. R., Martínez, R., et al. (2021) · Antioxidants · doi:10.3390/antiox10040577 · Cited by 13 · see citing works

Crosstalk between Peroxisomal Activities and Nrf2 Signaling in Porcine Embryos

Kim, E.-H., Ridlo, M. R., Lee, B. C., & Kim, G. A. (2021) · Antioxidants · doi:10.3390/antiox10050771 · Cited by 8 · see citing works

Meta-analysis of melatonin treatment and porcine somatic cell nuclear transfer embryo development

Guo, Z., Chen, W., Lv, L., et al. (2021) · Animal Reproduction · doi:10.1590/1984-3143-ar2021-0031 · Cited by 4 · see citing works

Is Melatonin the “Next Vitamin D”?: A Review of Emerging Science, Clinical Uses, Safety, and Dietary Supplements

Minich, D. M., Henning, M., Darley, C., Fahoum, M., Schuler, C. B., & Frame, J. (2022) · Nutrients · doi:10.3390/nu14193934 · Cited by 176 · see citing works

Melatonin secretion profile after experimental pineal gland compression in rats.

Mandera, M., Dec, R., Marcol, W., et al. (2003) · PubMed · Cited by 7 · see citing works

Small cell carcinoma cell lines contain opioid peptides and receptors

Roth, K. A., & Barchas, J. D. (1986) · Cancer · doi:10.1002/1097-0142(19860215)57:4 · Cited by 66 · see citing works

Antitumor Activity of the Pineal Gland: Effect of Unidentified Substances versus the Effect of Melatonin

Bartsch, H., Bartsch, C., Simon, W. E., Flehmig, B., EBELS, I., & Lippert, T. H. (2009) · Oncology · doi:10.1159/000227005 · Cited by 48 · see citing works

Melatonin Synthesis in the Hen Pineal Gland and its Control by Light

Axelrod, J., Wurtman, R. J., & Winget, C. M. (1964) · Nature · doi:10.1038/2011134a0 · Cited by 129 · see citing works

Complementary and Alternative Medicines Patients Are Talking About: Melatonin

Lee, C. C. O. (2006) · Clinical journal of oncology nursing · doi:10.1188/06.cjon.105-107 · Cited by 14 · see citing works