The Role of Psychosocial Interventions in Increasing Adherence to Tuberculosis Treatment in People Belonging to Socially Vulnerable Categories
Open accessAbstract
The article analyzes the effects of psychosocial interventions on adherence to tuberculosis (TB) treatment among vulnerable populations in Romania. The study includes 4104 patients from disadvantaged groups (rural, injecting drug users, homeless), beneficiaries of a national multidisciplinary support program. Multivariate analyses conducted on drug-susceptible TB (DS-TB) patients within this cohort identified some predictors of therapeutic success, such as extrapulmonary diagnosis, peer-to-peer educational support, and a higher level of education. At the same time, men, occupationally inactive people and those in the initial phase of treatment at project entry showed lower adherence. The results support the integration of psychosocial interventions in TB management.
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A scoping review is timely because the End TB Strategy and the WHO mhGAP framework have explicitly called for integration of mental health and psychosocial care into TB programs, while the number of primary trials and qualitative studies in this area has expanded substantially over the past five years.
“A scoping review is particularly timely now because the End TB Strategy [13] and the WHO mhGAP framework [17] have explicitly called for the integration of mental health and psychosocial care into TB programs, while the number of primary trials and qualitative studies in this area has expanded substantially over the past five years [18,19,20,21].”
From Psychosocial Interventions for Improving Treatment Adherence in Tuberculosis Patients: A Scoping Review of Evidence-Based Approaches. (2026) · cites this paper as [19]
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Experimental — accuracy not yet measuredMulticomponent interventions combining psychological support, education, and material or social assistance have apparent value for addressing multidimensional adherence barriers.
“The multidimensional nature of adherence barriers is also reflected in the apparent value of multicomponent interventions combining psychological support, education, and material or social assistance [16,19,36].”
From Psychosocial Interventions for Improving Treatment Adherence in Tuberculosis Patients: A Scoping Review of Evidence-Based Approaches. (2026) · cites this paper as [19]
Socially vulnerable groups, such as people who inject drugs and people experiencing homelessness, have markedly poorer treatment outcomes.
“The markedly poorer treatment outcomes reported among socially vulnerable groups, such as people who inject drugs and people experiencing homelessness [19], suggest that generalized support models may be insufficient for populations facing layered forms of disadvantage.”
From Psychosocial Interventions for Improving Treatment Adherence in Tuberculosis Patients: A Scoping Review of Evidence-Based Approaches. (2026) · cites this paper as [19]
Pragmatic implementation research involves trade-offs: real-world relevance may increase, while causal certainty remains limited when control groups are absent.
“More broadly, studies such as Munteanu et al. [19] illustrate the trade-offs typical of pragmatic implementation research: real-world relevance may increase, while causal certainty remains limited when control groups are absent.”
From Psychosocial Interventions for Improving Treatment Adherence in Tuberculosis Patients: A Scoping Review of Evidence-Based Approaches. (2026) · cites this paper as [19]
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Cites
Patient Adherence to Tuberculosis Treatment: A Systematic Review of Qualitative Research
Munro, S. A., Lewin, S. A., Smith, H. J., Engel, M. E., Fretheim, A., & Volmink, J. (2007) · PLoS Medicine · doi:10.1371/journal.pmed.0040238 · Cited by 1,080 · see citing works
Alipanah, N., Jarlsberg, L., Miller, C., Linh, N. N., Falzon, D., Jaramillo, E., & Nahid, P. (2018) · PLOS Medicine · doi:10.1371/journal.pmed.1002595 · Cited by 503 · see citing works
Hawkes, C., Ruel, M. T., Salm, L., Sinclair, B., & Branca, F. (2019) · The Lancet · doi:10.1016/s0140-6736(19)32506-1 · Cited by 471 · see citing works
Koyanagi, A., Vancampfort, D., Carvalho, A. F., DeVylder, J. E., Haro, J. M., Pizzol, D., Veronese, N., & Stubbs, B. (2017) · BMC Medicine · doi:10.1186/s12916-017-0975-5 · Cited by 131 · see citing works
Wingfield, T., Tovar, M. A., Huff, D., Boccia, D., Montoya, R., Ramos, E., Datta, S., Saunders, M. J., Lewis, J. J., Gilman, R. H., et al. (2017) · Bulletin of the World Health Organization · doi:10.2471/blt.16.170167 · Cited by 116 · see citing works
A study of prevalence of depression and anxiety in patients suffering from tuberculosis
Kumar, K., Kumar, A., Chandra, P., & Kansal, H. M. (2016) · Journal of Family Medicine and Primary Care · doi:10.4103/2249-4863.184641 · Cited by 61 · see citing works
Interventions to improve adherence to tuberculosis treatment: systematic review and meta-analysis
Müller, A. M., Osório, C. S., Silva, D. R., Sbruzzi, G., de Tarso, P., & Dalcin, P. D. T. R. (2018) · The International Journal of Tuberculosis and Lung Disease · doi:10.5588/ijtld.17.0596 · Cited by 47 · see citing works
Maynard, C., Tariq, S., Sotgiu, G., Migliori, G. B., van den Boom, M., & Field, N. (2023) · eClinicalMedicine · doi:10.1016/j.eclinm.2023.102057 · Cited by 44 · see citing works
Community-based active-case finding for tuberculosis: navigating a complex minefield
MacPherson, P., Shanaube, K., Phiri, M. D., Rickman, H. M., Horton, K. C., Feasey, H. R. A., Corbett, E. L., Burke, R. M., & Rangaka, M. X. (2024) · BMC Global and Public Health · doi:10.1186/s44263-024-00042-9 · Cited by 42 · see citing works
Farooq, S., Tunmore, J., & Comber, R. (2021) · Chronic Respiratory Disease · doi:10.1177/14799731211003937 · Cited by 31 · see citing works
Tuberculosis Surveillance in Romania Among Vulnerable Risk Groups Between 2015 and 2017
Munteanu, I., Cioran, N., van Hest, R., Abubakar, I., Story, A., Chiotan, D. I., de Vries, G., & Mahler, B. (2022) · Therapeutics and Clinical Risk Management · doi:10.2147/tcrm.s347748 · Cited by 31 · see citing works
Self-citationAgarwal, N., & Sarthi, P. (2020) · Journal of Family Medicine and Primary Care · doi:10.4103/jfmpc.jfmpc_1404_20 · Cited by 29 · see citing works
Building bridges: multidisciplinary teams in tuberculosis prevention and care
Ramos, J. P., Vieira, M., Pimentel, C., Argel, M., Barbosa, P., & Duarte, R. (2023) · Breathe · doi:10.1183/20734735.0092-2023 · Cited by 12 · see citing works
Koura, K. G., Tr�bucq, A., & Schwoebel, V. (2016) · The International Journal of Tuberculosis and Lung Disease · doi:10.5588/ijtld.16.0653 · Cited by 11 · see citing works
Fan, X., Zhang, X., Xu, H., Yang, F., Lau, J. T. F., Hao, C., Li, J., Zhao, Y., Hao, Y., & Gu, J. (2019) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph16224337 · Cited by 8 · see citing works
Kazibwe, A., Twinomugisha, F., Musaazi, J., Nakaggwa, F., Lukanga, D., Aleu, P., Kiyemba, T., Nkolo, A., Kirirabwa, N. S., Lopez, D. B. F., et al. (2021) · African Health Sciences · doi:10.4314/ahs.v21i3.3 · Cited by 7 · see citing works
Gao, J., Zhang, Y., Wang, X., Sun, Q., & Yin, J. (2023) · Public Health · doi:10.1016/j.puhe.2023.10.051 · Cited by 2 · see citing works
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Zabroski, J., Peptenatu, D., Mahler, B., Soliman, A. S., Gruia, A. K., Grecu, A., Munteanu, I., & Băloi, A. (2025) · Frontiers in Public Health · doi:10.3389/fpubh.2025.1711489 · Cited by 2 · see citing works
Self-citationBin Qamar, R. A., Pereira, H., & Alckmin-Carvalho, F. (2026) · Advances in respiratory medicine · doi:10.3390/arm94030032 · Cited by 1 · see citing works
“The multidimensional nature of adherence barriers is also reflected in the apparent value of multicomponent interventions combining psychological support, education, and material or social assistance [16,19,36].”
InfluentialDepressive Symptoms in Pediatric Tuberculosis: A Retrospective Two-Time-Point Observational Study
Mihailov, O. M., Stavăr-Matei, L., Țocu, G., Luțenco, V., Popovici, C. G., & Mihailov, R. (2026) · Diseases · doi:10.3390/diseases14050157
Ganesh, N., Radhakrishnan, R. K., Sumaira, F., Venugopal, J. P. G., Bhavani, P. K., Ranganathan, U. D., Hissar, S. S., Vankayalapati, R., & Kumar, N. P. (2026) · Medical Sciences · doi:10.3390/medsci14060613
- Authors
- Munteanu, I., Kalambayi, F., Toth, A., Dendrino, D., Burdusel, B., Vlasceanu, S.-G., Parliteanu, O., Dragomir, A., Nemes, R. M., & Mahler, B.
- Affiliations
- Titu Maiorescu University (RO)
- University of Bucharest (RO)
- Romanian Angel Appeal Foundation, 030956 Bucharest, Romania
- Pneumology Department, Marius Nasta Institute of Pneumology, 050159 Bucharest, Romania
- Cardio-Thoracic Department, Marius Nasta Institute of Pneumology, 050159 Bucharest, Romania
- Faculty of Medicine, Titu Maiorescu University, 021251 Bucharest, Romania
- Carol Davila University of Medicine and Pharmacy (RO)
- Institutul de Pneumoftiziologie "Marius Nasta" (RO)
- ORCID
- Venue
- Applied Sciences
- Publisher
- MDPI AG
- Published
- 2025-07-23
- Volume
- 15
- Issue
- 15
- Pages
- 8173
- ISSN
- 2076-3417 (ISSN-L)
- OpenAlex
- W4412595832
- Cited by
- 4
- References
- 17
- Citations by year
- 2026: 3 · 2025: 1
- FWCI
- 3.09
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Applied Sciences (publishedVersion, cc-by)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Topics
- Health Sciences › Medicine › Infectious Diseases › Tuberculosis Research and Epidemiology
- Health Sciences › Medicine › Family Practice › Medication Adherence and Compliance
- Health Sciences › Medicine › Infectious Diseases › HIV/AIDS Research and Interventions
- Keywords
- tuberculosis, medication adherence, psychosocial interventions, socially vulnerable populations, drug-susceptible tuberculosis, people who inject drugs, homelessness, rural patients, peer support, predictors of treatment success, Romania
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