The DOI matches its Crossref record; 55 of the 55 references it cites were found in a registry or an index.
The Effects of Vitamin D on Immune System and Inflammatory Diseases
Open accessAbstract
Immune cells, including dendritic cells, macrophages, and T and B cells, express the vitamin D receptor and 1α-hydroxylase. In vitro studies have shown that 1,25-dihydroxyvitamin D, the active form of vitamin D, has an anti-inflammatory effect. Recent epidemiological evidence has indicated a significant association between vitamin D deficiency and an increased incidence, or aggravation, of infectious diseases and inflammatory autoimmune diseases, such as rheumatoid arthritis, systemic lupus erythematosus, and multiple sclerosis. However, the impact of vitamin D on treatment and prevention, particularly in infectious diseases such as the 2019 coronavirus disease (COVID-19), remains controversial. Here, we review recent evidence associated with the relationship between vitamin D and inflammatory diseases and describe the underlying immunomodulatory effect of vitamin D.
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Cites
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Cited by
An Update on the Effects of Vitamin D on the Immune System and Autoimmune Diseases
Sîrbe, C., Rednic, S., Grama, A., & Pop, T. L. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23179784 · Cited by 269
Nutrition and immunity: perspectives on key issues and next steps
Dunbar, C. L., Aukema, H. M., Calder, P. C., Gibson, D. L., Henrickson, S. E., Khan, S., Mailhot, G., Panahi, S., Tabung, F. K., Tom, M., et al. (2023) · Applied Physiology, Nutrition, and Metabolism · doi:10.1139/apnm-2022-0276 · Cited by 24
Metadata
- Authors
- Ao, T., Kikuta, J., & Ishii, M.
- Venue
- Biomolecules
- Publisher
- MDPI AG
- Published
- 2021-11-03
- Volume
- 11
- Issue
- 11
- Pages
- 1624
- ISSN
- 2218-273X (ISSN-L)
- OpenAlex
- W3208956165
- Cited by
- 389
- References
- 55
- FWCI
- 31.81
- Type
- journal article
- Language
- en
- Open access
- gold
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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