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Cited by 361

The DOI matches its Crossref record; 234 of the 234 references it cites were found in a registry or an index.

Selenium and Selenoproteins in Health

Open access
Zhang, Fan, Li, Xuelian, Wei, Yumiao·2023·Biomolecules

Abstract

Selenium is a trace mineral that is essential for health. After being obtained from food and taken up by the liver, selenium performs various physiological functions in the body in the form of selenoproteins, which are best known for their redox activity and anti-inflammatory properties. Selenium stimulates the activation of immune cells and is important for the activation of the immune system. Selenium is also essential for the maintenance of brain function. Selenium supplements can regulate lipid metabolism, cell apoptosis, and autophagy, and have displayed significant alleviating effects in most cardiovascular diseases. However, the effect of increased selenium intake on the risk of cancer remains unclear. Elevated serum selenium levels are associated with an increased risk of type 2 diabetes, and this relationship is complex and nonlinear. Selenium supplementation seems beneficial to some extent; however, existing studies have not fully explained the influence of selenium on various diseases. Further, more intervention trials are needed to verify the beneficial or harmful effects of selenium supplementation in various diseases.

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Registry

Crossref · 10.3390/biom13050799

Cites

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Citations

Cites

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Metadata

Authors
Zhang, F., Li, X., & Wei, Y.
Venue
Biomolecules
Publisher
MDPI AG
Published
2023-05-08
Volume
13
Issue
5
Pages
799
ISSN
2218-273X (ISSN-L)
OpenAlex
W4378515660
Cited by
361
References
234
FWCI
51.79
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: Selenium and Selenoproteins in Health. https://app.cochat.ai/papers/10.3390/biom13050799
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Zhang, F., Li, X., & Wei, Y. (2023). Selenium and Selenoproteins in Health. Biomolecules. https://doi.org/10.3390/biom13050799

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.