The DOI matches its Crossref record; 132 of the 132 references it cites were found in a registry or an index.
Cancer-Associated Thrombosis: An Overview of Mechanisms, Risk Factors, and Treatment
Open accessAbstract
Cancer-associated thrombosis is a major cause of mortality in cancer patients, the most common type being venous thromboembolism (VTE). Several risk factors for developing VTE also coexist with cancer patients, such as chemotherapy and immobilisation, contributing to the increased risk cancer patients have of developing VTE compared with non-cancer patients. Cancer cells are capable of activating the coagulation cascade and other prothrombotic properties of host cells, and many anticancer treatments themselves are being described as additional mechanisms for promoting VTE. This review will give an overview of the main thrombotic complications in cancer patients and outline the risk factors for cancer patients developing cancer-associated thrombosis, focusing on VTE as it is the most common complication observed in cancer patients. The multiple mechanisms involved in cancer-associated thrombosis, including the role of anticancer drugs, and a brief outline of the current treatment for cancer-associated thrombosis will also be discussed.
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Citations
Cites
1 retracted
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RetractedNeutrophil Extracellular Traps Kill Bacteria
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Cited by
Brahmer, J. R., Abu-Sbeih, H., Ascierto, P. A., Brufsky, J., Cappelli, L. C., Cortazar, F. B., Gerber, D. E., Hamad, L., Hansen, E., Johnson, D. B., et al. (2021) · Journal for ImmunoTherapy of Cancer · doi:10.1136/jitc-2021-002435 · Cited by 917
Immune checkpoint inhibitors associated cardiovascular immune-related adverse events
Jo, W., Won, T., Daoud, A., & Čiháková, D. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1340373 · Cited by 55
Xu, M., Fei, J., Xiao, Z.-X., & Yi, Y. (2026) · Acta Biochimica et Biophysica Sinica · doi:10.3724/abbs.2025106 · Cited by 2
Metadata
- Authors
- Abdol Razak, N., Jones, G., Bhandari, M., Berndt, M., & Metharom, P.
- Venue
- Cancers
- Publisher
- MDPI AG
- Published
- 2018-10-11
- Volume
- 10
- Issue
- 10
- Pages
- 380
- ISSN
- 2072-6694 (ISSN-L)
- OpenAlex
- W2897723485
- Cited by
- 631
- References
- 132
- FWCI
- 36.43
- Type
- journal article
- Language
- en
- Open access
- gold
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- Abdol Razak, N., Jones, G., Bhandari, M., Berndt, M., & Metharom, P. (2018). Cancer-Associated Thrombosis: An Overview of Mechanisms, Risk Factors, and Treatment. Cancers. https://doi.org/10.3390/cancers10100380
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
