CoChat
Sign Up
Cited by 132

The DOI matches its Crossref record.

Recent Advances in Surface Functionalization of Magnetic Nanoparticles

Comanescu, Cezar·2023·Coatings
DOI 10.3390/coatings13101772
Open this paper in CoChat — free account

Abstract

In recent years, significant progress has been made in the surface functionalization of magnetic nanoparticles (MNPs), revolutionizing their utility in multimodal imaging, drug delivery, and catalysis. This progression, spanning over the last decade, has unfolded in discernible phases, each marked by distinct advancements and paradigm shifts. In the nascent stage, emphasis was placed on foundational techniques, such as ligand exchange and organic coatings, establishing the groundwork for subsequent innovations. This review navigates through the cutting-edge developments in tailoring MNP surfaces, illuminating their pivotal role in advancing these diverse applications. The exploration encompasses an array of innovative strategies such as organic coatings, inorganic encapsulation, ligand engineering, self-assembly, and bioconjugation, elucidating how each approach impacts or augments MNP performance. Notably, surface-functionalized MNPs exhibit increased efficacy in multimodal imaging, demonstrating improved MRI contrast and targeted imaging. The current review underscores the transformative impact of surface modifications on drug delivery systems, enabling controlled release, targeted therapy, and enhanced biocompatibility. With a comprehensive analysis of characterization techniques and future prospects, this review surveys the dynamic landscape of MNP surface functionalization over the past three years (2021–2023). By dissecting the underlying principles and applications, the review provides not only a retrospective analysis but also a forward-looking perspective on the potential of surface-engineered MNPs in shaping the future of science, technology, and medicine.

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.3390/coatings13101772

Cites

Statistics

Figures

Figure 1 General schematic diagram of MNPs' synthesis and functionalization. Figure 1. General schematic diagram of MNPs' synthesis and functionalization.
Figure 1 General schematic diagram of MNPs' synthesis and functionalization. Figure 1. General schematic diagram of MNPs' synthesis and functionalization.CC-BY · From the PDF
Image 2
CC-BY · From the PDF
Figure 3 Representative research direction in functionalized magnetic nanoparticles. Figure 3. Representative research direction in functionalized magnetic nanoparticles.
Figure 3 Representative research direction in functionalized magnetic nanoparticles. Figure 3. Representative research direction in functionalized magnetic nanoparticles.CC-BY · From the PDF
Image 4
CC-BY · From the PDF
Figure 5 Synthesis procedure for poly(2-(diethylamino) ethylmethacrylate) brushes capped with folic acid grafted on magnetic mesoporous silica nanoparticle (MMSNs) surfaces via SI-ARGET ATRP [44]. Figure 5. Synthesis procedure for poly(2-(diethylamino) ethylmethacrylate) brushes capped with folic acid grafted on magnetic mesoporous silica nanoparticle (MMSNs) surfaces via SI-ARGET ATRP [44]. Figure 5. Synthesis procedure for poly(2-(diethylamino) ethylmethacrylate) brushes capped with folic acid grafted on magnetic mesoporous silica nanoparticle (MMSNs) surfaces via SI-ARGET ATRP [44].
Figure 5 Synthesis procedure for poly(2-(diethylamino) ethylmethacrylate) brushes capped with folic acid grafted on magnetic mesoporous silica nanoparticle (MMSNs) surfaces via SI-ARGET ATRP [44]. Figure 5. Synthesis procedure for poly(2-(diethylamino) ethylmethacrylate) brushes capped with folic acid grafted on magnetic mesoporous silica nanoparticle (MMSNs) surfaces via SI-ARGET ATRP [44]. Figure 5. Synthesis procedure for poly(2-(diethylamino) ethylmethacrylate) brushes capped with folic acid grafted on magnetic mesoporous silica nanoparticle (MMSNs) surfaces via SI-ARGET ATRP [44].CC-BY · From the PDF
Figure 6 ( A ) Synthesis of PGICLCys and SPIONs and conjugation with folic acid (FA) or methotrexate (MTX). SPION@PGlCLCys_MTX: ( B ) drug delivery assay at lysosomal pH (pH 5.3) with or without protease (ENZ); ( C ) breast carcinoma-derived MDA-MB 231 cells viability after 72 h at different MTX concentrations. Reprinted under the terms and conditions of the Creative Commons Attribution (CC BY) license from ref. [90]. Figure 6. ( A ) Synthesis of PGICLCys and SPIONs and conjugation with folic acid (FA) or methotrexate (MTX). SPION@PGlCLCys_MTX: ( B ) drug delivery assay at lysosomal pH (pH 5.3) with or without protease (ENZ); ( C ) breast carcinoma-derived MDA-MB 231 cells viability after 72 h at different MTX concentrations. Reprinted under the terms and conditions of the Creative Commons Attribution (CC BY) license from ref. [90].
Figure 6 ( A ) Synthesis of PGICLCys and SPIONs and conjugation with folic acid (FA) or methotrexate (MTX). SPION@PGlCLCys_MTX: ( B ) drug delivery assay at lysosomal pH (pH 5.3) with or without protease (ENZ); ( C ) breast carcinoma-derived MDA-MB 231 cells viability after 72 h at different MTX concentrations. Reprinted under the terms and conditions of the Creative Commons Attribution (CC BY) license from ref. [90]. Figure 6. ( A ) Synthesis of PGICLCys and SPIONs and conjugation with folic acid (FA) or methotrexate (MTX). SPION@PGlCLCys_MTX: ( B ) drug delivery assay at lysosomal pH (pH 5.3) with or without protease (ENZ); ( C ) breast carcinoma-derived MDA-MB 231 cells viability after 72 h at different MTX concentrations. Reprinted under the terms and conditions of the Creative Commons Attribution (CC BY) license from ref. [90].CC-BY · From the PDF
Image 7
CC-BY · From the PDF
Figure 8 The main parameters and features that need to be addressed by future MNP nanoplatforms for efficient use in biomedical applications and beyond. Figure 8. The main parameters and features that need to be addressed by future MNP nanoplatforms for efficient use in biomedical applications and beyond.
Figure 8 The main parameters and features that need to be addressed by future MNP nanoplatforms for efficient use in biomedical applications and beyond. Figure 8. The main parameters and features that need to be addressed by future MNP nanoplatforms for efficient use in biomedical applications and beyond.CC-BY · From the PDF

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

No references could be resolved yet.

Research works printed but not linked: 104

  1. Jiang, K.Y., Zhang, L.L., and Bao, G. (2021). Magnetic iron oxide nanoparticles for biomedical applications. Curr. Opin. Biomed. Eng., 20. · DOI
  2. Shankar, M., Kesavan, S.S., and Biswas, K. (2023). Exploring the Potentials of Magnetic Nanoscale Material for Different Biomedical Applications: A Review. Bionanoscience. · DOI
  3. Matveeva, V.G., and Bronstein, L.M. (2021). Magnetic Nanoparticle-Containing Supports as Carriers of Immobilized Enzymes: Key Factors Influencing the Biocatalyst Performance. Nanomaterials, 11. · DOI
  4. Palade, P., Comanescu, C., and Radu, C. (2023). Synthesis of Nickel and Cobalt Ferrite-Doped Graphene as Efficient Catalysts for Improving the Hydrogen Storage Kinetics of Lithium Borohydride. Materials, 16. · DOI
  5. Pryazhnikov, 2021, Surface-Modified Magnetic Nanoscale Materials: Preparation and Study of Their Structure, Composition, and Properties, J. Anal. Chem., 76, 685, 10.1134/S1061934821060095 · DOI
  6. Ansari, 2022, Synthesis and Stability of Magnetic Nanoparticles, Bionanoscience, 12, 627, 10.1007/s12668-022-00947-5 · DOI
  7. Siddique, S., and Chow, J.C.L. (2022). Recent Advances in Functionalized Nanoparticles in Cancer Theranostics. Nanomaterials, 12. · DOI
  8. Comanescu, 2022, Magnetic Nanoparticles: Current Advances in Nanomedicine, Drug Delivery and MRI, Chemistry, 4, 872, 10.3390/chemistry4030063 · DOI
  9. Senthilkumar, 2021, Designing magnetic nanoparticles for in vivo applications and understanding their fate inside human body, Coordin. Chem. Rev., 445, 214082, 10.1016/j.ccr.2021.214082 · DOI
  10. Liu, Y.K., Su, G.M.Y., Zhang, R.Y., Dai, R.J., and Li, Z. (2023). Nanomaterials-Functionalized Hydrogels for the Treatment of Cutaneous Wounds. Int. J. Mol. Sci., 24. · DOI
  11. Gambhir, 2022, Multifunctional surface functionalized magnetic iron oxide nanoparticles for biomedical applications: A review, Appl. Surf. Sci. Adv., 11, 100303, 10.1016/j.apsadv.2022.100303 · DOI
  12. Gwon, 2023, Size effect of iron oxide nanorods with controlled aspect ratio on magneto-responsive behavior, J. Ind. Eng. Chem., 124, 279, 10.1016/j.jiec.2023.04.017 · DOI
  13. Granada, 2023, Biomimetic magnetic nanoparticles for bacterial magnetic concentration in liquids and qPCR-detection, Food Control, 147, 109623, 10.1016/j.foodcont.2023.109623 · DOI
  14. Franzel, 2012, Synthesis of magnetic nanoparticles by pulsed laser ablation, Appl. Surf. Sci., 261, 332, 10.1016/j.apsusc.2012.08.010 · DOI
  15. Liu, 2020, High-moment magnetic nanoparticles, J. Nanopart. Res., 22, 66, 10.1007/s11051-020-4758-0 · DOI
  16. Carvallo, 2023, Magnetic and structural properties of biogenic magnetic nanoparticles along their production process for use in magnetic hyperthermia, J. Magn. Magn. Mater., 575, 170726, 10.1016/j.jmmm.2023.170726 · DOI
  17. Iacob, 2020, Optimization of magnetic fluid hyperthermia with respect to nanoparticle shape-related parameters: Case of magnetite ellipsoidal nanoparticles, J. Nanopart. Res., 22, 138, 10.1007/s11051-020-04842-6 · DOI
  18. 2023, The Use of Capping Agents in the Stabilization and Functionalization of Metallic Nanoparticles for Biomedical Applications, Part. Part. Syst. Charact., 40, 2200146, 10.1002/ppsc.202200146 · DOI
  19. Lu, 2007, Magnetic Nanoparticles: Synthesis, Protection, Functionalization, and Application, Angew. Chem. Int. Ed., 46, 1222, 10.1002/anie.200602866 · DOI
  20. Majidi, 2016, Current methods for synthesis of magnetic nanoparticles, Artif. Cells Nanomed. Biotechnol., 44, 722, 10.3109/21691401.2014.982802 · DOI
  21. Gareev, K., Tagaeva, R., Bobkov, D., Yudintceva, N., Goncharova, D., Combs, S.E., Ten, A., Samochernych, K., and Shevtsov, M. (2023). Passing of Nanocarriers across the Histohematic Barriers: Current Approaches for Tumor Theranostics. Nanomaterials, 13. · DOI
  22. Hao, 2021, Biomimetic nanomedicine toward personalized disease theranostics, Nano Res., 14, 2491, 10.1007/s12274-020-3265-z · DOI
  23. Palade, P., Comanescu, C., Kuncser, A., Berger, D., Matei, C., Iacob, N., and Kuncser, V. (2020). Mesoporous Cobalt Ferrite Nanosystems Obtained by Surfactant-Assisted Hydrothermal Method: Tuning Morpho-structural and Magnetic Properties via pH-Variation. Nanomaterials, 10. · DOI
  24. Aslam, 2022, Current and future perspectives of multifunctional magnetic nanoparticles based controlled drug delivery systems, J. Drug Deliv. Sci. Technol., 67, 102946, 10.1016/j.jddst.2021.102946 · DOI
  25. Hur, 2022, Self-assembled core-shell Fe3O4-Pt nanoparticles via silylation/polymerization-based amino-functionalization, Colloid Interfac. Sci., 50, 100655, 10.1016/j.colcom.2022.100655 · DOI
  26. Low, 2022, Stimuli-controllable iron oxide nanoparticle assemblies: Design, manipulation and bio-applications, J. Control Release, 345, 231, 10.1016/j.jconrel.2022.03.024 · DOI
  27. Strassburg, 2022, Functionalization of biopolymer fibers with magnetic nanoparticles, Phys. Sci. Rev., 7, 1091
  28. Darroudi, M., Gholami, M., Rezayi, M., and Khazaei, M. (2021). An overview and bibliometric analysis on the colorectal cancer therapy by magnetic functionalized nanoparticles for the responsive and targeted drug delivery. J. Nanobiotechnol., 19. · DOI
  29. Mahajan, R., Suriyanarayanan, S., and Nicholls, I.A. (2021). Improved Solvothermal Synthesis of gamma-Fe2O3 Magnetic Nanoparticles for SiO2 Coating. Nanomaterials, 11. · DOI
  30. Elahi, 2021, Progress and prospects of magnetic iron oxide nanoparticles in biomedical applications: A review, Artif. Organs, 45, 1272, 10.1111/aor.14027 · DOI
  31. Yousefiasl, 2022, Stem cell membrane-coated abiotic nanomaterials for biomedical applications, J. Control Release, 351, 174, 10.1016/j.jconrel.2022.09.012 · DOI
  32. Das, 2021, Biomedical Applications of Functional Polyaspartamide-Based Materials, ACS Appl. Polym. Mater., 3, 4791, 10.1021/acsapm.1c00785 · DOI
  33. Klekotka, U., Zambrzycka-Szelewa, E., Satula, D., and Kalska-Szostko, B. (2021). Stability Studies of Magnetite Nanoparticles in Environmental Solutions. Materials, 14. · DOI
  34. Zakhireh, 2022, Bioactive Chitosan-Based Organometallic Scaffolds for Tissue Engineering and Regeneration, Topics Curr. Chem., 380, 13, 10.1007/s41061-022-00364-y · DOI
  35. Kwizera, 2022, Magnetic Nanoparticle-Mediated Heating for Biomedical Applications, J. Heat Trans.-T Asme, 144, 030801, 10.1115/1.4053007 · DOI
  36. Hu, B., Rotherham, M., Farrow, N., Roach, P., Dobson, J., and El Haj, A.J. (2022). Immobilization of Wnt Fragment Peptides on Magnetic Nanoparticles or Synthetic Surfaces Regulate Wnt Signaling Kinetics. Int. J. Mol. Sci., 23. · DOI
  37. Mohapatra, A., Uthaman, S., and Park, I.K. (2021). External and Internal Stimuli-Responsive Metallic Nanotherapeutics for Enhanced Anticancer Therapy. Front. Mol. Biosci., 7. · DOI
  38. Kothandaraman, 2022, Functionalization and Haemolytic analysis of pure superparamagnetic magnetite nanoparticle for hyperthermia application, J. Biol. Phys., 48, 383, 10.1007/s10867-022-09614-y · DOI
  39. Duong, 2023, Magnetic heating of water dispersible and size-controlled superparamagnetic cobalt iron oxide nanoparticles, Powder Technol., 427, 118720, 10.1016/j.powtec.2023.118720 · DOI
  40. Ghosal, 2022, A Detailed Review on Synthesis, Functionalization, Application, Challenges, and Current Status of Magnetic Nanoparticles in the Field of Drug Delivery and Gene Delivery System, AAPS PharmSciTech, 24, 25, 10.1208/s12249-022-02485-5 · DOI
  41. Arias-Ramos, N., Ibarra, L.E., Serrano-Torres, M., Yague, B., Caverzan, M.D., Chesta, C.A., Palacios, R.E., and Lopez-Larrubia, P. (2021). Iron Oxide Incorporated Conjugated Polymer Nanoparticles for Simultaneous Use in Magnetic Resonance and Fluorescent Imaging of Brain Tumors. Pharmaceutics, 13. · DOI
  42. Avarand, 2021, A quantum chemical study on the magnetic nanocarrier-tirapazamine drug delivery system, Nanosyst.-Phys. Chem. M, 12, 167, 10.17586/2220-8054-2021-12-2-167-174 · DOI
  43. Beagan, A.M., Alghamdi, A.A., Lahmadi, S.S., Halwani, M.A., Almeataq, M.S., Alhazaa, A.N., Alotaibi, K.M., and Alswieleh, A.M. (2021). Folic Acid-Terminated Poly(2-Diethyl Amino Ethyl Methacrylate) Brush-Gated Magnetic Mesoporous Nanoparticles as a Smart Drug Delivery System. Polymers, 13. · DOI
  44. Valls-Chivas, A., Gomez, J., Garcia-Peiro, J.I., Hornos, F., and Hueso, J.L. (2023). Enzyme-Iron Oxide Nanoassemblies: A Review of Immobilization and Biocatalytic Applications. Catalysts, 13. · DOI
  45. Belleti, 2021, Synthesis of bioluminescent gold nanoparticle-luciferase hybrid systems for technological applications, Photoch. Photobio Sci., 20, 1439, 10.1007/s43630-021-00111-0 · DOI
  46. Boosz, P., Pfister, F., Stein, R., Friedrich, B., Fester, L., Band, J., Muhlberger, M., Schreiber, E., Lyer, S., and Dudziak, D. (2021). Citrate-Coated Superparamagnetic Iron Oxide Nanoparticles Enable a Stable Non-Spilling Loading of T Cells and Their Magnetic Accumulation. Cancers, 13. · DOI
  47. Cheah, 2021, The key role of reaction temperature on a polyol synthesis of water-dispersible iron oxide nanoparticles, J. Magn. Magn. Mater., 540, 168481, 10.1016/j.jmmm.2021.168481 · DOI
  48. Correa, 2021, A rapid and simple preparation of amphotericin B-loaded bacterial magnetite nanoparticles, RSC Adv., 11, 28000, 10.1039/D1RA03950D · DOI
  49. Dhavale, 2021, Chitosan coated magnetic nanoparticles as carriers of anticancer drug Telmisartan: pH-responsive controlled drug release and cytotoxicity studies, J. Phys. Chem. Solids, 148, 109749, 10.1016/j.jpcs.2020.109749 · DOI
  50. Domagalski, 2021, Magnetic nanoparticle decorated anodic alumina nanotubes for fluorescent detection of cathepsin B, J. Colloid Interf. Sci., 584, 236, 10.1016/j.jcis.2020.09.109 · DOI
  51. Doswald, 2021, Preparation of Functionalized Carbon-Coated Cobalt Nanoparticles with Sulfonated Arene Derivatives, a Study on Surface Functionalization and Stability, Chem.-Eur. J., 27, 4108, 10.1002/chem.202004631 · DOI
  52. Ehsanimehr, 2021, PEI grafted Fe3O4@SiO2@SBA-15 labeled FA as a pH-sensitive mesoporous magnetic and biocompatible nanocarrier for targeted delivery of doxorubicin to MCF-7 cell line, Colloid Surface A, 615, 126302, 10.1016/j.colsurfa.2021.126302 · DOI
  53. Fan, X.M., Shen, J.J., Xu, Y.Y., Gao, J., and Zhang, Y.W. (2021). Metabolic integration of azide functionalized glycan on Escherichia coli cell surface for specific covalent immobilization onto magnetic nanoparticles with click chemistry. Bioresour. Technol., 324. · DOI
  54. Fernandez-Ponce, C., Manuel, J.M., Fernandez-Cisnal, R., Felix, E., Beato-Lopez, J., Munoz-Miranda, J.P., Beltran, A.M., Santos, A.J., Morales, F.M., and Yeste, M.P. (2021). Superficial Characteristics and Functionalization Effectiveness of Non-Toxic Glutathione-Capped Magnetic, Fluorescent, Metallic and Hybrid Nanoparticles for Biomedical Applications. Metals, 11. · DOI
  55. Habra, K., McArdle, S.E.B., Morris, R.H., and Cave, G.W.V. (2021). Synthesis and Functionalisation of Superparamagnetic Nano-Rods towards the Treatment of Glioblastoma Brain Tumours. Nanomaterials, 11. · DOI
  56. Jose, 2021, The synthesis and characterisation of curcumin loaded Ag ((1-X)) Ni (X) Fe-2 O-4 for drug delivery, Mater. Technol., 36, 339, 10.1080/10667857.2020.1758477 · DOI
  57. Kannan, 2021, Nickel Ferrite Nanoparticles as an Adsorbent for Immobilized Metal Affinity Chromatography of Proteins, J. Chromatogr. Sci., 59, 262, 10.1093/chromsci/bmaa102 · DOI
  58. Leitner, 2021, Polymer Brush-Grafted Nanoparticles Preferentially Interact with Opsonins and Albumin, ACS Appl. Bio Mater., 4, 795, 10.1021/acsabm.0c01355 · DOI
  59. Martin, D.S., Oropesa-Nunez, R., and de la Torre, T.Z.G. (2021). Evaluating the Performance of a Magnetic Nanoparticle-Based Detection Method Using Circle-to-Circle Amplification. Biosensors, 11. · DOI
  60. Moskvin, 2021, In vitro cellular activity of maghemite/cerium oxide magnetic nanoparticles with antioxidant properties, Colloid Surface B, 204, 111824, 10.1016/j.colsurfb.2021.111824 · DOI
  61. Nayeem, 2021, Silica coating of iron oxide magnetic nanoparticles by reverse microemulsion method and their functionalization with cationic polymer P (NIPAm-co-AMPTMA) for antibacterial vancomycin immobilization, Colloid Surface A, 611, 125857, 10.1016/j.colsurfa.2020.125857 · DOI
  62. Reyes-Ortega, F., Delgado, A.V., and Iglesias, G.R. (2021). Modulation of the Magnetic Hyperthermia Response Using Different Superparamagnetic Iron Oxide Nanoparticle Morphologies. Nanomaterials, 11. · DOI
  63. Rezaei, 2021, Quantum chemical analysis of 5-aminolevulinic acid anticancer drug delivery systems: Carbon nanotube, -COOH functionalized carbon nanotube and iron oxide nanoparticle, J. Mol. Liq., 340, 117182, 10.1016/j.molliq.2021.117182 · DOI
  64. Veloso, S.R.S., Silva, J.F.G., Hilliou, L., Moura, C., Coutinho, P.J.G., Martins, J.A., Testa-Anta, M., Salgueirino, V., Correa-Duarte, M.A., and Ferreira, P.M.T. (2021). Impact of Citrate and Lipid-Functionalized Magnetic Nanoparticles in Dehydropeptide Supramolecular Magnetogels: Properties, Design and Drug Release. Nanomaterials, 11. · DOI
  65. Wu, 2021, Stable and Monodisperse Iron Nitride Nanoparticle Suspension for Magnetic Diagnosis and Treatment: Development of Synthesis and Surface Functionalization Strategies, ACS Appl. Nano Mater., 4, 4409, 10.1021/acsanm.0c03421 · DOI
  66. Zare, 2021, Chitosan-functionalized Fe3O4 nanoparticles as an excellent biocompatible nanocarrier for silymarin delivery, Polym. Adv. Technol., 32, 4094, 10.1002/pat.5416 · DOI
  67. Zarinwall, A., Asadian-Birjand, M., Seleci, D.A., Maurer, V., Trautner, A., Garnweitner, G., and Fuchs, H. (2021). Magnetic Nanoparticle-Based Dianthin Targeting for Controlled Drug Release Using the Endosomal Escape Enhancer SO1861. Nanomaterials, 11. · DOI
  68. Zhalechin, 2021, Magnetic polymeric core-shell as a carrier for gradual release in-vitro test drug delivery, Heliyon, 7, e06652, 10.1016/j.heliyon.2021.e06652 · DOI
  69. Zuk, M., Gaweda, W., Majkowska-Pilip, A., Osial, M., Wolski, M., Bilewicz, A., and Krysinski, P. (2021). Hybrid Radiobioconjugated Superparamagnetic Iron Oxide-Based Nanoparticles for Multimodal Cancer Therapy. Pharmaceutics, 13. · DOI
  70. Ali, 2022, Sugar based cationic magnetic core-shell silica nanoparticles for nucleic acid extraction, RSC Adv., 12, 13566, 10.1039/D2RA01139E · DOI
  71. Behr, J., Carnell, L.R., Stein, R., Pfister, F., Friedrich, B., Huber, C., Lyer, S., Band, J., Schreiber, E., and Alexiou, C. (2022). In Vitro Setup for Determination of Nanoparticle-Mediated Magnetic Cell and Drug Accumulation in Tumor Spheroids under Flow Conditions. Cancers, 14. · DOI
  72. Bin Jang, S., Jin, S.M., Kim, H.S., Jeong, Y.Y., Lee, S.J., Hahn, S., Lee, H., Lee, H.S., Kim, J.H., and Lee, D.Y. (2022). DAMP-modulating nanoparticle for successful pancreatic islet and stem cell transplantation. Biomaterials, 287. · DOI
  73. Gupta, 2022, Tuneable magnetic nanocomposites for remote self-healing, Sci. Rep., 12, 10180, 10.1038/s41598-022-14135-8 · DOI
  74. Ikram, 2022, Synthesis and characterization of hematite (alpha-Fe2O3) reinforced polylactic acid (PLA) nanocomposites for biomedical applications, Compos. Part C-Open, 9, 100331
  75. Liu, 2022, Multifunctional magnetic nanocarriers for delivery of siRNA and shRNA plasmid to mammalian cells: Characterization, adsorption and release behaviors, Colloid Surface B, 219, 112861, 10.1016/j.colsurfb.2022.112861 · DOI
  76. Miola, 2022, In situ reduction of Ag on magnetic nanoparticles with gallic acid: Effect of the synthesis parameters on morphology, Nanomedicine, 17, 499, 10.2217/nnm-2021-0479 · DOI
  77. Mun, 2023, CD44 and CD221 directed magnetic cubosomes for the targeted delivery of helenalin to rhabdomyosarcoma cells, Nano Res., 16, 2915, 10.1007/s12274-022-5037-4 · DOI
  78. Mushtaq, 2022, Magnetoelectric core-shell CoFe2O4@BaTiO3 nanorods: Their role in drug delivery and effect on multidrug resistance pump activity in vitro, RSC Adv., 12, 24958, 10.1039/D2RA03429H · DOI
  79. Nayak, 2022, Thiolated β-cyclodextrin modified iron oxide nanoparticles for effective targeted cancer therapy, Mater. Today Commun., 33, 104644, 10.1016/j.mtcomm.2022.104644 · DOI
  80. Rocha, J.M.V., de Souza, V.B., Panunto, P.C., Nicolosi, J.S., da Silva, E.D., Cadore, S., Londono, O.M., Muraca, D., Tancredi, P., and de Brot, M. (2022). In vitro and in vivo acute toxicity of a novel citrate-coated magnetite nanoparticle. PLoS ONE, 17. · DOI
  81. Swain, 2022, Effect of beta-cyclodextrin decoration on structural, optical and magnetic properties of luminescent magnetic nanoparticles and its application as a drug carrier, J. Mol. Struct., 1247, 131330, 10.1016/j.molstruc.2021.131330 · DOI
  82. Szymczyk, A., Drozd, M., Kaminska, A., Matczuk, M., Trzaskowski, M., Mazurkiewicz-Pawlicka, M., Ziolkowski, R., and Malinowska, E. (2022). Comparative Evaluation of Different Surface Coatings of Fe3O4-Based Magnetic Nano Sorbent for Applications in the Nucleic Acids Extraction. Int. J. Mol. Sci., 23. · DOI
  83. Tang, 2022, Synergistic Integration and Pharmacomechanical Function of Enzyme-Magnetite Nanoparticle Swarms for Low-Dose Fast Thrombolysis, Small, 18, 2202848, 10.1002/smll.202202848 · DOI
  84. Pando, 2022, Novel magnetic beads with improved performance for Alzheimer’s disease biomarker detection, Microchem. J., 175, 107211, 10.1016/j.microc.2022.107211 · DOI
  85. Treder, 2022, Effects of Fe3O4 Magnetic Nanoparticle Functionalization with Ionic Liquids and a Double-Chained Surfactant on the Pretreatment of Plasma Samples during Drug Extraction, Anal. Chem., 94, 16587, 10.1021/acs.analchem.2c01985 · DOI
  86. Urquizo, 2022, Effect of Aminosilane Nanoparticle Coating on Structural and Magnetic Properties and Cell Viability in Human Cancer Cell Lines, Part. Part. Syst. Charact., 39, 2200106, 10.1002/ppsc.202200106 · DOI
  87. Valdivia, V., Gimeno-Ferrero, R., Leal, M.P., Paggiaro, C., Fernandez-Romero, A.M., Gonzalez-Rodriguez, M.L., and Fernandez, I. (2022). Biologically Relevant Micellar Nanocarrier Systems for Drug Encapsulation and Functionalization of Metallic Nanoparticles. Nanomaterials, 12. · DOI
  88. Zohreh, 2022, Fabrication of a magnetic nanocarrier for doxorubicin delivery based on hyperbranched polyglycerol and carboxymethyl cellulose: An investigation on the effect of borax cross-linker on pH-sensitivity, Int. J. Biol. Macromol., 203, 80, 10.1016/j.ijbiomac.2022.01.150 · DOI
  89. Beltrame, J.M., Ribeiro, B.B.P., Guindani, C., Candiotto, G., Felipe, K.B., Lucas, R., Zottis, A.D., Isoppo, E., Sayer, C., and de Araujo, P.H.H. (2023). Coating of SPIONs with a Cysteine-Decorated Copolyester: A Possible Novel Nanoplatform for Enzymatic Release. Pharmaceutics, 15. · DOI
  90. Chauhan, 2023, Polypropylene sulphide coating on magnetic nanoparticles as a novel platform for excellent biocompatible, stimuli-responsive smart magnetic nanocarriers for cancer therapeutics, Nanoscale, 15, 7384, 10.1039/D2NR05218K · DOI
  91. Jalali, 2023, Synthesis of Magnetic Nanocarrier Conjugated by Folate Based on Tragacanth and In Vitro Investigation of their Efficiency on Breast Cancer Cells, Starch-Starke, 75, 2200092, 10.1002/star.202200092 · DOI
  92. Liu, 2023, Preparation of PEI-modified nanoparticles by dopamine self-polymerization for efficient DNA delivery, Biotechnol. Appl. Biochem., 70, 824, 10.1002/bab.2402 · DOI
  93. Nguyen, 2023, Aggregation of magnetic nanoparticles functionalized with trans-resveratrol in aqueous solution, Discov. Nano, 18, 64, 10.1186/s11671-023-03805-9 · DOI
  94. Kovrigina, E., Poletaeva, Y., Zheng, Y., Chubarov, A., and Dmitrienko, E. (2023). Nylon-6-Coated Doxorubicin-Loaded Magnetic Nanoparticles and Nanocapsules for Cancer Treatment. Magnetochemistry, 9. · DOI
  95. Baldea, I., Petran, A., Florea, A., Sevastre-Berghian, A., Nenu, I., Filip, G.A., Cenariu, M., Radu, M.T., and Iacovita, C. (2023). Magnetic Nanoclusters Stabilized with Poly[3,4-Dihydroxybenzhydrazide] as Efficient Therapeutic Agents for Cancer Cells Destruction. Nanomaterials, 13. · DOI
  96. Urquizo, 2023, Enhancing the Cytocompatibility of Cobalt-Iron Ferrite Nanoparticles Through Chemical Substitution and Surface Modification, Adv. Mater. Interfaces, 10, 2300206, 10.1002/admi.202300206 · DOI
  97. Toderascu, L.I., Sima, L.E., Orobeti, S., Florian, P.E., Icriverzi, M., Maraloiu, V.-A., Comanescu, C., Iacob, N., Kuncser, V., and Antohe, I. (2023). Synthesis and Anti-Melanoma Activity of L-Cysteine-Coated Iron Oxide Nanoparticles Loaded with Doxorubicin. Nanomaterials, 13. · DOI
  98. Xu, 2022, Doping engineering and functionalization of iron oxide nanoclusters for biomedical applications, J. Alloys Compd., 923, 166459, 10.1016/j.jallcom.2022.166459 · DOI
  99. Upadhyay, K., Tamrakar, R.K., Thomas, S., and Kumar, M. (2023). Surface functionalized nanoparticle A boon to biomedical science. Chem.-Biol. Interact., 380. · DOI
  100. Popova, V., Dmitrienko, E., and Chubarov, A. (2023). Magnetic Nanocomposites and Imprinted Polymers for Biomedical Applications of Nucleic Acids. Magnetochemistry, 9. · DOI
  101. Rojas, 2021, The Use of Iron Oxide Nanoparticles to Reprogram Macrophage Responses and the Immunological Tumor Microenvironment, Front. Immunol., 12, 693709, 10.3389/fimmu.2021.693709 · DOI
  102. Bilal, 2022, Surface-coated magnetic nanostructured materials for robust bio-catalysis and biomedical applications-A review, J. Adv. Res., 38, 157, 10.1016/j.jare.2021.09.013 · DOI
  103. Bohara, 2016, Role of functionalization: Strategies to explore potential nano-bio applications of magnetic nanoparticles, RSC Adv., 6, 43989, 10.1039/C6RA02129H · DOI
  104. Mittal, N., Kundu, A., and Pathania, A.R. (2023). A review of the chemical synthesis of magnetic nano-particles and biomedical applications. Mater. Today Proc. · DOI

Cited by

Sorted by citations

Metadata

Authors
Comanescu, C.
Venue
Coatings
Publisher
MDPI AG
Published
2023-10-15
Volume
13
Issue
10
Pages
1772
ISSN
2079-6412
DOI
10.3390/coatings13101772
Cited by
132
References
0
Language
en
Licence
creativecommons.org/licenses/by/4.0/ (vor)
Funders
  • Romanian Ministry of Research and Innovation (PN-III-P1-1.1-TE-2021-1657 (TE 84/2022), TE 91/2022, PC1-PN23080101)
  • Core Program of the National Institute of Materials Physics (PN-III-P1-1.1-TE-2021-1657 (TE 84/2022), TE 91/2022, PC1-PN23080101)

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review