The DOI matches its Crossref record; 23 of the 23 references it cites were found in a registry or an index.
Mechanism of Cuticle Hole Development in Human Hair Due to UV-Radiation Exposure
Open accessAbstract
Hair is easily damaged by ultraviolet (UV) radiation, bleaching agents or permanent wave treatments, and as damage progresses, hair loses its gloss, develops split ends and breaks. However, the causes of hair damage due to UV radiation have not yet been clarified. We discovered that in one mechanism facilitating damage to wet hair by UV radiation, the unsaturated fatty acids in wet hair produce hydroxy radicals upon exposure to UV radiation, and these radicals produce cuticle holes between the cuticle layers. In wet hair exposed to UV radiation, cuticle holes were produced only between the cuticle layers, whereas when human hair was immersed in a solution containing hydroxy radicals produced by Fenton’s reaction, a random production of cuticle holes was noted. It is thought that hydroxy radicals are produced only between the cuticle layers by exposure to UV radiation, and cuticle holes are formed only in this region because one of the polyunsaturated fatty acids, linoleic acid, with a bis-allyl hydrogen, is found between the cuticle layers.
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“The more sealed the layers are, the healthier the hair is [44].”
From On the Path to Sustainable Cosmetics: Development of a Value-Added Formulation of Solid Shampoo Incorporating Mango Peel Extract (2023) · cites this paper as [44]
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Cites
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Morphological degradation of human hair cuticle due to simulated sunlight irradiation and washing
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Sorted by citations
UV and visible light exposure to hair leads to widespread changes in the hair lipidome
Ross, A. B., Maes, E., Lee, E. J., Homewood, I., Marsh, J., Davis, S. L., & Willicut, R. J. (2022) · International Journal of Cosmetic Science · doi:10.1111/ics.12810 · Cited by 19
New insights into human hair: SAXS, SEM, TEM and EDX for Alopecia Areata investigations
Coroabǎ, A., Chiriac, A. E., Săcărescu, L., Pinteala, T., Minea, B., Ibanescu, S., Perțea, M., Moraru, A. C., Eşanu, I., Maier, S. S., et al. (2020) · PeerJ · doi:10.7717/peerj.8376 · Cited by 16
Brito, I., Ferreira, S. M., & Santos, L. (2023) · Cosmetics · doi:10.3390/cosmetics10050140 · Cited by 15
Performance and Mechanism of Hydrolyzed Keratin for Hair Photoaging Prevention
Fan, J., Wu, L., Wang, J., Bian, X., Chen, C., & Chang, K. (2025) · Molecules · doi:10.3390/molecules30051182 · Cited by 12
Analysis of Lipids in the Medulla of Japanese Hair and Their Function
Ymazaki, J., & Maeda, K. (2018) · Cosmetics · doi:10.3390/cosmetics5020027 · Cited by 12
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Metadata
- Authors
- Maeda, K., Yamazaki, J., Okita, N., Shimotori, M., Igarashi, K., & Sano, T.
- Affiliations
- Tokyo University of Technology (JP)
- Corresponding author
- Maeda, Kazuhisa
- ORCID
- Maeda, Kazuhisa
- Venue
- Cosmetics
- Publisher
- MDPI AG
- Published
- 2018-03-21
- Volume
- 5
- Issue
- 2
- Pages
- 24
- ISSN
- 2079-9284 (ISSN-L)
- OpenAlex
- W2790180083
- Cited by
- 16
- References
- 23
- Citations by year
- 2026: 1 · 2025: 4 · 2024: 2 · 2023: 3 · 2022: 2 · 2021: 2 · 2020: 1 · 2018: 1
- FWCI
- 0.80
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Cosmetics (publishedVersion, cc-by)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Topics
- Physical Sciences › Materials Science › Polymers and Plastics › Dyeing and Modifying Textile Fibers
- Health Sciences › Medicine › Dermatology › Skin Protection and Aging
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Skin and Cellular Biology Research
- Keywords
- hair damage, ultraviolet radiation, hair cuticle, hydroxyl radicals, Fenton reaction, unsaturated fatty acids, linoleic acid, polyunsaturated fatty acids, hair bleaching, split ends
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