Analysis of Dyes in Cosmetics: Challenges and Recent Developments
Open accessAbstract
Colour plays a decisive role in the marketing of a cosmetic product. Among thousands of substances used to colour, synthetic dyes are the most widespread in the industry. Their potential secondary effects on human health and different regulatory requirements for their use between the main world markets make analytical control necessary to guarantee the safety of a cosmetic product. However, methodologies for the determination of dyes in cosmetics are scarce with respect to those reported for other cosmetic ingredients such as preservatives or ultraviolet UV filters. In addition, most of the existing methods just consider a part of the total of dyes regulated. On the other hand, many methods have been developed for matrices different than cosmetics such as foodstuff, beverages or wastewater. The current paper reviews the recent developments in analytical methodologies for the control of synthetic dyes in cosmetics proposed in the international scientific literature in the last 10 years (2008–2018). A trend towards the use of miniaturized extraction techniques is evidenced. Due to the hydrophilic nature of dyes, liquid chromatography is the most usual choice in combination with absorbance detectors and, more recently, with mass spectrometry.
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Experimental studies have found a positive relationship between exposure to heavy metals and nervous system changes such as oxidative stress, shortness of breath, memory, vision, and/or cognitive impairment, autonomic component imbalance, muscle cramps, and headache.
“Experimental studies have found a positive relationship between exposure to heavy metals and some changes in the nervous system, such as oxidative stress, shortness of breath, memory, vision, and/or cognitive impairment, autonomic component imbalance, muscle cramps, and headache.”
From The dark side of beauty: an in-depth analysis of the health hazards and toxicological impact of synthetic cosmetics and personal care products (2024) · cites this paper as [57]
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- Authors
- Guerra, E., Llompart, M., & Garcia-Jares, C.
- Affiliations
- Universidade de Santiago de Compostela (ES)
- Laboratory of Research and Development of Analytical Solutions (LIDSA), Department of Analytical Chemistry, Nutrition and Food Science, Faculty of Chemistry, Universidade de Santiago de Compostela, E-15782 Santiago de Compostela, Spain
- ORCID
- Llompart, Maria
- Venue
- Cosmetics
- Publisher
- MDPI AG
- Published
- 2018-07-23
- Volume
- 5
- Issue
- 3
- Pages
- 47
- ISSN
- 2079-9284 (ISSN-L)
- OpenAlex
- W2883804655
- Cited by
- 183
- References
- 40
- Citations by year
- 2026: 18 · 2025: 32 · 2024: 42 · 2023: 24 · 2022: 30 · 2021: 19 · 2020: 9 · 2019: 9
- FWCI
- 5.77
- Type
- journal article
- Language
- en
- Open access
- gold
- dx.doi.org
- Licence
- Locations
- Cosmetics (publishedVersion, cc-by)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- Ministerio de Economía, Industria y Competitividad, Gobierno de España (CTQ2013-46545-P)
- Xunta de Galicia (GPC2017/04)
- Topics
- Physical Sciences › Chemistry › Analytical Chemistry › Dye analysis and toxicity
- Physical Sciences › Chemistry › Analytical Chemistry › Analytical Methods in Pharmaceuticals
- Physical Sciences › Chemistry › Analytical Chemistry › Analytical chemistry methods development
- Keywords
- synthetic dyes, dye determination, analytical methods, miniaturized extraction, liquid chromatography, mass spectrometry, absorbance detection, cosmetic safety, regulatory control
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