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Cited by 11Gestational Diabetes Research and ManagementCOVID-19 Impact on ReproductionDiabetes, Cardiovascular Risks, and Lipoproteins

Prevalence of Gestational Diabetes in preCOVID-19 and COVID-19 Years and Its Impact on Pregnancy: A 5-Year Retrospective Study

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Chelu, Sorina, Bernad, Elena, Craina, Marius, Neamtu, Radu, Mocanu, Adelina Geanina, Vernic, Corina, Chiriac, Veronica Daniela, Tomescu, Larisa +1 more·2022·Diagnostics
DOI 10.3390/diagnostics12051241PMC PMC9140441
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Abstract

Gestational diabetes mellitus (GDM) affects a total of 3% to 9% of all pregnancies. It has a high impact on both mother and baby, increases the perinatal risks, and predicts the presence of long-term chronic metabolic complications. The aim of our study is to determine the incidence of GDM in tertiary hospitals in the west part of Romania to lay out the risk factors associated with GDM and to observe the evolution of pregnancy among patients with this pathology by emphasizing the state of birth of the fetus, the birth weight, and the way of birth. We also want to compare the prevalence of GDM in preCOVID-19 (Coronavirus disease) versus COVID-19 years. The study took place between January 2017 and December 2021 at the Municipal Emergency Hospital of Timisoara, Romania. The proportion of births with GDM was significantly increased during the COVID-19 period compared to the preCOVID-19 period (chi2 Fisher exact test, p < 0.001). The period 2020–2021 represents a significant risk factor for GDM births (OR = 1.87, with 95% CI = [1.30, 2.67]). COVID years represent a risk period for developing gestational diabetes, which can be explained by reduced physical activity, anxiety, or modified dietary habits, even if the follow-up period was not impacted.

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  • In Romania, Chelu et al. presented data from 2017 to 2021 with average GDM prevalence 5.78%, lowest 2.77% in 2017 and highest 8.48% in 2021.

    “Chelu et al. presented data from 2017 to 2021, in which the average GDM prevalence was estimated at 5.78% with the lowest result of 2.77% in 2017 and the highest outcome in 2021 at 8.48% [167].”

    From Evolution of Gestational Diabetes Mellitus across Continents in 21st Century (2022) · cites this paper as [167]

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  1. [1]Chiefari E. Quaresima P. Visconti F. Mirabelli M. Brunetti A. Gestational diabetes and fetal overgrowth: Time to rethink screening guidelines Lancet Diabetes Endocrinol. 2020 8 561 562 10.1016/S2213-8587(20)30189-3 32559469 · DOI
  2. [2]Han Y. Tong M. Jin L. Yu J. Meng W. Ren A. Maternal age at pregnancy and risk for gestational diabetes mellitus among Chinese women with singleton pregnancies Int. J. Diabetes Dev. Ctries. 2020 41 114 120 10.1007/s13410-020-00859-8 · DOI
  3. [4]Chu S.Y. Callaghan W.M. Kim S.Y. Schmid C.H. Lau J. England L.J. Dietz P.M. Maternal Obesity and Risk of Gestational Diabetes Mellitus Diabetes Care 2007 30 2070 2076 10.2337/dc06-2559a 17416786 · DOI · Paper page
  4. [7]Ogurtsova K. Da Rocha Fernandes J.D. Huang Y. Linnenkamp U. Guariguata L. Cho N.H. Cavan D. Shaw J.E. Makaroff L.E. IDF Diabetes Atlas: Global estimates for the prevalence of diabetes for 2015 and 2040 Diabetes Res. Clin. Pract. 2017 128 40 50 10.1016/j.diabres.2017.03.024 28437734 · DOI
  5. [8]López-de-Andrés A. Perez-Farinos N. Hernández-Barrera V. Palomar-Gallego M.A. Carabantes-Alarcón D. Zamorano-León J.J. Miguel-Diez D. Jimenez-Garcia R. A population-based study of diabetes during pregnancy in Spain (2009–2015): Trends in incidence, obstetric interventions, and pregnancy outcomes J. Clin. Med. 2020 9 582 10.3390/jcm9020582 PMC7074053 32098048 · DOI · Paper page
  6. [9]Mackin S.T. Nelson S.M. Kerssens J.J. Wood R. Wild S. Colhoun H.M. Leese G.P. Philip S. Lindsay R.S. Diabetes and pregnancy: National trends over a 15 year period Diabetologia 2018 61 1081 1088 10.1007/s00125-017-4529-3 29322220 PMC6448996 · DOI
  7. [10]American Diabetes Association Introduction: Standards of Medical Care in Diabetes—2022 Diabetes Care 2021 45 S1 S2 10.2337/dc22-Sint 34964812 · DOI · Paper page
  8. [11]Li G. Wei T. Ni W. Zhang A. Zhang J. Xing Y. Xing Q. Incidence and risk factors of gestational diabetes mellitus: A prospective cohort study in Qingdao, China Front. Endocrinol. 2020 11 636 10.3389/fendo.2020.00636 33042010 PMC7516372 · DOI
  9. [12]Garabedian C. Deruelle P. Delivery (timing, route, peripartum glycemic control) in women with gestational diabetes mellitus Diabetes Metab. 2010 36 515 521 10.1016/j.diabet.2010.11.005 21163417 · DOI
  10. [13]Mills J.L. Malformations in infants of diabetic mothers Teratology 1982 25 385 394 10.1002/tera.1420250316 7051398 · DOI
  11. [14]Kucera J. Rate and type of congenital anomalies among offspring of diabetic women J. Reprod. Med. 1971 7 73 82 5095696
  12. [15]Dude A.M. Badreldin N. Schieler A. Yee L.M. Periconception glycemic control and congenital anomalies in women with pregestational diabetes BMJ Open Diabetes Res. Care 2021 9 e001966 10.1136/bmjdrc-2020-001966 33888543 PMC8070859 · DOI
  13. [16]Zhu C. Liu Y. Wu H. Overexpression of circACTR2 in Gestational Diabetes Mellitus Predicts Intrauterine Death, Fetal Malformation, and Intrauterine Infection Diabetes Metab. Syndr. Obes. 2021 14 4655 10.2147/DMSO.S316043 34876825 PMC8643146 · DOI
  14. [17]Gasim T. Gestational Diabetes Mellitus: Maternal and Perinatal Outcomes in 220 Saudi Women Oman Med. J. 2012 27 140 144 10.5001/omj.2012.29 22496940 PMC3321340 · DOI
  15. [18]Kanguru L. Bezawada N. Hussein J. Bell J. The burden of diabetes mellitus during pregnancy in low- and middle-income countries: A systematic review Glob. Health Action 2014 7 23987 10.3402/gha.v7.23987 24990684 PMC4079934 · DOI
  16. [19]Al-Hakeem M.M. Pregnancy outcome of gestational diabetic mothers: Experience in a tertiary center J. Fam. Community Med. 2006 13 55 59 PMC3410064 23012105
  17. [20]Metzger B.E. Coustan D.R. Trimble E.R. Hyperglycemia and adverse pregnancy outcomes Clin. Chem. 2019 65 937 938 10.1373/clinchem.2019.303990 30996054 · DOI
  18. [22]Kc K. Shakya S. Zhang H. Gestational Diabetes Mellitus and Macrosomia: A Literature Review Ann. Nutr. Metab. 2015 66 (Suppl. S2) 14 20 10.1159/000371628 26045324 · DOI
  19. [23]Bashir M. Ibrahim I. Eltaher F. Beer S. Baagar K. Aboulfotouh M. Konje J.C. Abou-Samra A.-B. Screening pregnant women in a high-risk population with WHO-2013 or NICE diagnostic criteria does not affect the prevalence of gestational diabetes Sci. Rep. 2021 11 1 7 10.1038/s41598-021-84918-y 33692395 PMC7946879 · DOI
  20. [25]Villar J. Ariff S. Gunier R.B. Thiruvengadam R. Rauch S. Kholin A. Roggero P. Prefumo F. Vale M.S.D. Cardona-Perez J.A. Maternal and Neonatal Morbidity and Mortality Among Pregnant Women with and without COVID-19 Infection: The INTERCOVID Multinational Cohort Study JAMA Pediatr. 2021 175 817 826 10.1001/jamapediatrics.2021.1050 33885740 PMC8063132 · DOI
  21. [26]Li Y. Ren X. He L. Li J. Zhang S. Chen W. Maternal age and the risk of gestational diabetes mellitus: A systematic review and meta-analysis of over 120 million participants Diabetes Res. Clin. Pract. 2020 162 108044 10.1016/j.diabres.2020.108044 32017960 · DOI · Paper page
  22. [27]Catalano P.M. Roman N.M. Tyzbir E.D. Merritt A.O. Driscoll P. Amini S.B. Weight gain in women with gestational diabetes Obstet. Gynecol. 1993 81 523 528 8459960
  23. [28]Kong L. Nilsson I.A. Gissler M. Lavebratt C. Associations of Maternal Diabetes and Body Mass Index with Offspring Birth Weight and Prematurity JAMA Pediatr. 2019 173 371 378 10.1001/jamapediatrics.2018.5541 30801637 PMC6450270 · DOI
  24. [30]D’Ambrosio V. Brunelli R. Vena F. Di Mascio D. Marchetti C. Boccherini C. Piccioni M.G. Panici P.B. Giancotti A. Metformin reduces maternal weight gain in obese pregnant women: A systematic review and meta-analysis of two randomized controlled trials Diabetes/Metab. Res. Rev. 2019 35 e3164 10.1002/dmrr.3164 30945418 · DOI
  25. [31]Eskenazi B. Rauch S. Iurlaro E. Gunier R.B. Albertina R.E.G.O. Gravett M.G. Cavoretto P.I. Deruelle P. García-May P.K. Mhatre M. Diabetes mellitus, maternal adiposity, and insulin-dependent gestational diabetes are associated with COVID-19 in pregnancy: The INTERCOVID Study Am. J. Obstet. Gynecol. 2021 in press 10.1016/j.ajog.2021.12.032 34942154 PMC8686449 · DOI
  26. [32]Schummers L. Hutcheon J.A. Hacker M.R. VanderWeele T.J. Williams P.L. McElrath T.A. Hernandez-Diaz S. Absolute risks of obstetric outcomes risks by maternal age at first birth: A population-based cohort Epidemiology 2018 29 379 387 10.1097/EDE.0000000000000818 29517506 PMC5922259 · DOI · Paper page
  27. [33]Wang Y. Chen L. Xiao K. Horswell R. Besse J. Johnson J. Ryan D.H. Hu G. Increasing incidence of gestational diabetes mellitus in Louisiana, 1997–2009 J. Women’s Health 2012 21 319 325 10.1089/jwh.2011.2838 22023415 · DOI
  28. [34]Balsells M. Garcia-Patterson A. Gich I. Corcoy R. Major congenital malformations in women with gestational diabetes mellitus: A systematic review and meta-analysis Diabetes/Metab. Res. Rev. 2012 28 252 257 10.1002/dmrr.1304 22052679 · DOI
  29. [35]Mitrović M. Stojić S. Tešić D.S. Popović Đ. Rankov O. Tomić-Naglić D. Novaković-Paro J. Pejin R. Bulatović S. Todorović-Veljić M. The impact of diabetes mellitus on the course and outcome of pregnancy during a 5-year follow-up Vojnosanit. Pregl. 2014 71 907 914 10.2298/VSP1410907M 25518268 · DOI
  30. [37]Committee on Practice Bulletins—Obstetrics ACOG Practice Bulletin No. 190 Summary: Gestational Diabetes Mellitus Obs. Gynecol. 2018 131 406 408 10.1097/AOG.0000000000002498 29370044 · DOI

Cited by

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Authors
Chelu, S., Bernad, E., Craina, M., Neamtu, R., Mocanu, A. G., Vernic, C., Chiriac, V. D., Tomescu, L., & Borza, C.
Affiliations
  • Victor Babeș University of Medicine and Pharmacy Timișoara (RO)
  • Discipline of Obstetrics and Gynecology, Victor Babes University of Medicine and Pharmacy Timisoara, 300041 Timisoara, Romania
Corresponding author
Chiriac, Veronica Daniela
ORCID
Venue
Diagnostics
Publisher
MDPI AG
Published
2022-05-16
Volume
12
Issue
5
Pages
1241
ISSN
2075-4418 (ISSN-L)
DOI
10.3390/diagnostics12051241
PMC
PMC9140441
OpenAlex
W4280649275
Cited by
11
References
6
Citations by year
2026: 2 · 2025: 1 · 2024: 3 · 2023: 3 · 2022: 2
FWCI
2.26
Type
journal article
Language
en
Open access
Licence
Locations
  • Diagnostics (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Topics
  • Health Sciences › Medicine › Obstetrics and Gynecology › Gestational Diabetes Research and Management
  • Health Sciences › Medicine › Obstetrics and Gynecology › COVID-19 Impact on Reproduction
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
Keywords
gestational diabetes mellitus, prevalence, COVID-19 pandemic, risk factors, perinatal outcomes, birth weight, mode of delivery, pregnancy outcomes, physical inactivity, anxiety, dietary habits, Romania

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