Medicinal Traits of the Phenolic Compound from Foeniculum vulgare for Oligomenorrhea
Open accessAbstract
A phenolic compound in Foeniculum vulgare can improve human health. Foeniculum vulgar contains flavonoids, glycosides, and other constituents that are used for medicinal ailments. Trans-anethole, fenchone, and estragole essential oils are the main ingredients in F. vulgare seeds. The principle component of fennel oil, anethole, has structural similarity with the synthetic oestrogen diethylstilbestrol, making it an active estrogenic agent. Women with PCOS may exhibit obesity, amenorrhea, oligomenorrhea, infertility, or androgenic features, which are characterized by the absence of ovulation and hyperandrogenism. Oligomenorrhea is a kind of irregular menstruation period. Treatment of oligomenorrhea depends on the causes; the main cause of oligomenorrhea is the presence of polycystic ovarian syndrome (PCOS), with 75–85%experiencing infrequent periods. This mini-review focuses on F. vulgare seeds as an advantageous addition to treat PCOS. Women with PCOS also have a lower level of the hormone progesterone due to the absence or reduction in ovulation. Numerous phytoestrogens can be found in F.vulgare seeds; with less insulin resistance and lower blood sugar level, fennel phytoestrogen content is beneficial. It is also thought to aid in reducing the cellularim balance that causes PCOS’s metabolic abnormalities.
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Fennel has potential therapeutic effects in PCOS due to its phytoestrogenic properties, which may weakly mimic estrogen and influence metabolic and hormonal regulation.
“Fennel (Foeniculum vulgare) is another herb with potential therapeutic effects in PCOS due to its phytoestrogenic properties, which may weakly mimic estrogen and influence metabolic and hormonal regulation [205].”
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- Authors
- Patil, J., Patil, D., Sayyed, H., Patil, M., & Mali, R.
- Affiliations
- Department of Pharmacognosy & Phytochemistry, PSG Vidya Prasarak Mandal’s College of Pharmacy, Shahada 425409, India
- Department of Quality Assurance, PSG Vidya Prasarak Mandal’s College of Pharmacy, Shahada 425409, India
- Senior Executive, Formulation Research and Development, Bliss GVS Pharma Ltd., Andheri, Mumbai 400072, India
- Corresponding author
- Patil, Javesh
- Patil, Devyani
- Venue
- The 26th International Electronic Conference on Synthetic Organic Chemistry
- Publisher
- MDPI
- Published
- 2022-11-21
- Pages
- 54
- OpenAlex
- W4319035508
- Cited by
- 6
- References
- 19
- Citations by year
- 2026: 1 · 2025: 4 · 2024: 1
- FWCI
- 9.60
- Type
- conference paper
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- International Electronic Conference on Synthetic Organic Chemistry (ECSOC) (publishedVersion, cc-by)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
- Topics
- Health Sciences › Medicine › Reproductive Medicine › Ovarian function and disorders
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Plant chemical constituents analysis
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Medicinal Plant Research
- Keywords
- fennel, fennel seeds, oligomenorrhea, polycystic ovary syndrome, phytoestrogens, anethole, estragole, fenchone, essential oils, flavonoids, insulin resistance, progesterone, menstrual irregularity
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