The DOI matches its Crossref record; 35 of the 35 references it cites were found in a registry or an index.
Comparison of Potentially Inappropriate Medications for People with Dementia at Admission and Discharge during An Unplanned Admission to Hospital: Results from the SMS Dementia Study
Open accessAbstract
People with dementia (PWD) and cognitive impairment are particularly vulnerable to medication problems, and unplanned admission to hospital presents an opportunity to address polypharmacy, potentially inappropriate medications (PIMs) and anticholinergic burden. This study aimed to compare PIMS and other medication data for PWD to determine whether these changed during hospitalization. Medications documented in patient's records at admission and discharge were evaluated for PWD recruited to phase one of a prospective quasi-experimental pre/post-controlled trial that was conducted at two regional hospitals in NSW, Australia. The study sample included PWD or cognitive impairment having an unplanned admission to hospital. Data were collected using a purpose developed audit tool for medications and PIMs, and a Modified Anticholinergic Burden Scale. Total participants were 277, and results determined that the cognitive status of PWD is not always detected during an unplanned admission. This may make them more vulnerable to medication problems and poor outcomes. Polypharmacy and PIMS for PWD were high at admission and significantly reduced at discharge. However, PWD should be routinely identified as high risk at admission; and there is potential to further reduce polypharmacy and PIMs during admission to hospital, particularly psychotropic medications at discharge. Future studies should focus on evaluating targeted interventions designed to increase medication safety for PWD.
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“Transitions into hospital from home or care settings also offered missed opportunities for medication review and optimization (Kable et al., 2019).”
From Mind the gap: a systematic review of barriers, facilitators, and experiences of care transitions for people living with dementia and their informal caregivers. (2026) · cites this paper as Kable et al., 2019
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Clarifying Confusion: The Confusion Assessment Method: A New Method for Detection of Delirium
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What is polypharmacy? A systematic review of definitions
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Six-item screener to identify cognitive impairment among potential subjects for clinical research
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Development of the Swedish anticholinergic burden scale (Swe-ABS)
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Metadata
- Authors
- Kable, A., Fullerton, A., Fraser, S., Palazzi, K., Hullick, C., Oldmeadow, C., Pond, D., Searles, A., Edmunds, K., Attia, J., & On behalf of SMS Dementia Study investigators
- Affiliations
- University of Newcastle Australia (AU)
- Hunter New England Local Health District (AU)
- Hunter Medical Research Institute (AU)
- Corresponding author
- Kable, Ashley
- ORCID
- Venue
- Healthcare
- Publisher
- MDPI AG
- Published
- 2019-01-09
- Volume
- 7
- Issue
- 1
- Pages
- 8
- ISSN
- 2227-9032 (ISSN-L)
- PMC
- PMC6473531
- OpenAlex
- W2909054827
- Cited by
- 24
- References
- 35
- Citations by year
- 2026: 3 · 2025: 2 · 2024: 1 · 2023: 6 · 2022: 4 · 2021: 2 · 2020: 6
- FWCI
- 1.58
- Type
- journal article
- Language
- en
- Open access
- gold
- dx.doi.org
- Licence
- Locations
- Healthcare (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
- Griffith Research Online (submittedVersion, cc-by)
- Funders
- Australian Government Dementia and Aged Care Services Fund (1601301)
- Topics
- Health Sciences › Medicine › Geriatrics and Gerontology › Pharmaceutical Practices and Patient Outcomes
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Health Sciences › Medicine › Geriatrics and Gerontology › Geriatric Care and Nursing Homes
- Keywords
- dementia, potentially inappropriate medications, polypharmacy, anticholinergic burden, emergency admissions, drug safety, cognitive impairment, psychotropic drugs, hospital discharge
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