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Current Strategies to Improve the Bioactivity of PEEK
Open accessAbstract
The synthetic thermoplastic polymer polyetheretherketone (PEEK) is becoming a popular component of clinical orthopedic and spinal applications, but its practical use suffers from several limitations. Although PEEK is biocompatible, chemically stable, radiolucent and has an elastic modulus similar to that of normal human bone, it is biologically inert, preventing good integration with adjacent bone tissues upon implantation. Recent efforts have focused on increasing the bioactivity of PEEK to improve the bone-implant interface. Two main strategies have been used to overcome the inert character of PEEK. One approach is surface modification to activate PEEK through surface treatment alone or in combination with a surface coating. Another strategy is to prepare bioactive PEEK composites by impregnating bioactive materials into PEEK substrate. Researchers believe that modified bioactive PEEK will have a wide range of orthopedic applications.
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Cited by
A Multimaterial Scaffold With Tunable Properties: Toward Bone Tissue Repair
Feng, P., Wu, P., Gao, C., Yang, Y., Guo, W., Yang, W., & Shuai, C. (2018) · Advanced Science · doi:10.1002/advs.201700817 · Cited by 365
Liu, C., Li, Y., Wang, J., Liu, C., Liu, W., & Jian, X. (2018) · Molecules · doi:10.3390/molecules23071643 · Cited by 30
Metadata
- Authors
- Ma, R., & Tang, T.
- Venue
- International Journal of Molecular Sciences
- Publisher
- MDPI AG
- Published
- 2014-03-28
- Volume
- 15
- Issue
- 4
- Pages
- 5426-5445
- ISSN
- 1422-0067 (ISSN-L)
- OpenAlex
- W2069453298
- Cited by
- 491
- References
- 0
- FWCI
- 12.58
- Type
- journal article
- Language
- en
- Open access
- gold
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- Ma, R., & Tang, T. (2014). Current Strategies to Improve the Bioactivity of PEEK. International Journal of Molecular Sciences. https://doi.org/10.3390/ijms15045426
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
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