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Dielectrophoresis for Bioparticle Manipulation

Open access
Qian, Cheng, Huang, Haibo, Chen, Liguo, Li, Xiangpeng, Ge, Zunbiao, Chen, Tao, Yang, Zhan, Sun, Lining·2014·International Journal of Molecular Sciences

Abstract

As an ideal method to manipulate biological particles, the dielectrophoresis (DEP) technique has been widely used in clinical diagnosis, disease treatment, drug development, immunoassays, cell sorting, etc. This review summarizes the research in the field of bioparticle manipulation based on DEP techniques. Firstly, the basic principle of DEP and its classical theories are introduced in brief; Secondly, a detailed introduction on the DEP technique used for bioparticle manipulation is presented, in which the applications are classified into five fields: capturing bioparticles to specific regions, focusing bioparticles in the sample, characterizing biomolecular interaction and detecting microorganism, pairing cells for electrofusion and separating different kinds of bioparticles; Thirdly, the effect of DEP on bioparticle viability is analyzed; Finally, the DEP techniques are summarized and future trends in bioparticle manipulation are suggested.

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Cites

  • Electromechanics of Particles

    Jones, T. B. (1995) · doi:10.1017/cbo9780511574498 · Cited by 2,786 · cited 1×

    “If the electric field is non-uniform, a net force will act on the particle to drive the particle to move toward/against the direction of the electric field maxima [11].”
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Metadata

Authors
Qian, C., Huang, H., Chen, L., Li, X., Ge, Z., Chen, T., Yang, Z., & Sun, L.
Venue
International Journal of Molecular Sciences
Publisher
MDPI AG
Published
2014-10-10
Volume
15
Issue
10
Pages
18281-18309
ISSN
1422-0067 (ISSN-L)
OpenAlex
W2069278072
Cited by
190
References
1
FWCI
7.61
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: Dielectrophoresis for Bioparticle Manipulation. https://app.cochat.ai/papers/10.3390/ijms151018281
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Qian, C., Huang, H., Chen, L., Li, X., Ge, Z., Chen, T., Yang, Z., & Sun, L. (2014). Dielectrophoresis for Bioparticle Manipulation. International Journal of Molecular Sciences. https://doi.org/10.3390/ijms151018281

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