The DOI matches its Crossref record; 101 of the 101 references it cites were found in a registry or an index.
Osteoarthritis in the XXIst Century: Risk Factors and Behaviours that Influence Disease Onset and Progression
Open accessAbstract
Osteoarthritis (OA) is a growing public health problem across the globe, affecting more than half of the over 65 population. In the past, OA was considered a wear and tear disease, leading to the loss of articular cartilage and joint disability. Nowadays, thanks to advancements in molecular biology, OA is believed to be a very complex multifactorial disease. OA is a degenerative disease characterized by “low-grade inflammation” in cartilage and synovium, resulting in the loss of joint structure and progressive deterioration of cartilage. Although the disease can be dependent on genetic and epigenetic factors, sex, ethnicity, and age (cellular senescence, apoptosis and lubricin), it is also associated with obesity and overweight, dietary factors, sedentary lifestyle and sport injuries. The aim of this review is to highlight how certain behaviors, habits and lifestyles may be involved in the onset and progression of OA and to summarize the principal risk factors involved in the development of this complicated joint disorder.
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Abramoff, B., & Caldera, F. E. (2020) · Medical Clinics of North America · doi:10.1016/j.mcna.2019.10.007 · Cited by 1,191
Articular fibrocartilage - Why does hyaline cartilage fail to repair?
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Metadata
- Authors
- Musumeci, G., Aiello, F., Szychlinska, M., Di Rosa, M., Castrogiovanni, P., & Mobasheri, A.
- Venue
- International Journal of Molecular Sciences
- Publisher
- MDPI AG
- Published
- 2015-03-16
- Volume
- 16
- Issue
- 3
- Pages
- 6093-6112
- ISSN
- 1422-0067 (ISSN-L)
- OpenAlex
- W2004752183
- Cited by
- 397
- References
- 101
- FWCI
- 21.63
- Type
- journal article
- Language
- en
- Open access
- gold
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- Musumeci, G., Aiello, F., Szychlinska, M., Di Rosa, M., Castrogiovanni, P., & Mobasheri, A. (2015). Osteoarthritis in the XXIst Century: Risk Factors and Behaviours that Influence Disease Onset and Progression. International Journal of Molecular Sciences. https://doi.org/10.3390/ijms16036093
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
