The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
Recent Advances in Momordica charantia: Functional Components and Biological Activities
Open accessAbstract
Momordica charantia L. (M. charantia), a member of the Cucurbitaceae family, is widely distributed in tropical and subtropical regions of the world. It has been used in folk medicine for the treatment of diabetes mellitus, and its fruit has been used as a vegetable for thousands of years. Phytochemicals including proteins, polysaccharides, flavonoids, triterpenes, saponins, ascorbic acid and steroids have been found in this plant. Various biological activities of M. charantia have been reported, such as antihyperglycemic, antibacterial, antiviral, antitumor, immunomodulation, antioxidant, antidiabetic, anthelmintic, antimutagenic, antiulcer, antilipolytic, antifertility, hepatoprotective, anticancer and anti-inflammatory activities. However, both in vitro and in vivo studies have also demonstrated that M. charantia may also exert toxic or adverse effects under different conditions. This review addresses the chemical constituents of M. charantia and discusses their pharmacological activities as well as their adverse effects, aimed at providing a comprehensive overview of the phytochemistry and biological activities of M. charantia.
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Cites
Singer, A. J., & Clark, R. A. F. (1999) · New England Journal of Medicine · doi:10.1056/nejm199909023411006 · Cited by 6,106
Diagnosis and classification of diabetes mellitus
American Diabetes Association (2010) · Diabetes Care · doi:10.2337/dc10-s062 · Cited by 5,491
Medicinal plants of India with anti-diabetic potential
Grover, J. K., Yadav, S., & Vats, V. (2002) · Journal of Ethnopharmacology · doi:10.1016/s0378-8741(02)00059-4 · Cited by 1,798
Momordica charantia: A popular health-promoting vegetable with multifunctionality
Wang, S., Li, Z., Yang, G., Ho, C.-T., & Li, S. (2017) · Food & Function · doi:10.1039/c6fo01812b · Cited by 104
Cited by
Yan, J.-K., Wu, L.-X., Qiao, Z.-R., Cai, W.-D., & Ma, H. (2019) · Food Chemistry · doi:10.1016/j.foodchem.2018.08.012 · Cited by 298
Hu, Z., Li, F., Zhou, X., Zhang, F., Huang, L., Gu, B., Shen, J., & Qi, S. (2020) · Stem Cell Research & Therapy · doi:10.1186/s13287-020-02000-2 · Cited by 47
Self-citationKrawczyk, M., Burzynska-Pedziwiatr, I., Wozniak, L. A., & Bukowiecka-Matusiak, M. (2022) · Current Issues in Molecular Biology · doi:10.3390/cimb44020049 · Cited by 28
Evaluation of acute and sub-chronic toxicity of bitter melon seed extract in Wistar rats
Chung, W.-Y., Jadhav, S., Hsu, P.-K., & Kuan, C.-M. (2022) · Toxicology Reports · doi:10.1016/j.toxrep.2022.04.024 · Cited by 19
Metadata
- Authors
- Jia, S., Shen, M., Zhang, F., & Xie, J.
- Venue
- International Journal of Molecular Sciences
- Publisher
- MDPI AG
- Published
- 2017-11-28
- Volume
- 18
- Issue
- 12
- Pages
- 2555
- ISSN
- 1422-0067 (ISSN-L)
- OpenAlex
- W2769874622
- Cited by
- 421
- References
- 4
- FWCI
- 13.75
- Type
- journal article
- Language
- en
- Open access
- gold
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- Jia, S., Shen, M., Zhang, F., & Xie, J. (2017). Recent Advances in Momordica charantia: Functional Components and Biological Activities. International Journal of Molecular Sciences. https://doi.org/10.3390/ijms18122555
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