Role of PD-L1 Expression in Non-Small Cell Lung Cancer and Their Prognostic Significance according to Clinicopathological Factors and Diagnostic Markers

Pawelczyk, Konrad; Piotrowska, Aleksandra; Ciesielska, Urszula; Jablonska, Karolina; Glatzel-Plucinska, Natalia; Grzegrzolka, Jedrzej; Podhorska-Okolow, Marzenna; Dziegiel, Piotr; Nowinska, Katarzyna

doi:10.3390/ijms20040824

Role of PD-L1 Expression in Non-Small Cell Lung Cancer and Their Prognostic Significance according to Clinicopathological Factors and Diagnostic Markers

Background: The latest immunotherapy, used in the treatment of non-small cell lung cancer (NSCLC), uses monoclonal antibodies directed against programmed death ligand 1 (PD-L1) to inhibit its interaction with the PD-1 receptor. Elevated levels of PD-L1 expression were observed on NSCLC cells. The…