The DOI matches its Crossref record; 529 of the 529 references it cites were found in a registry or an index.
Antimicrobial Peptides: An Update on Classifications and Databases
Open accessAbstract
Antimicrobial peptides (AMPs) are distributed across all kingdoms of life and are an indispensable component of host defenses. They consist of predominantly short cationic peptides with a wide variety of structures and targets. Given the ever-emerging resistance of various pathogens to existing antimicrobial therapies, AMPs have recently attracted extensive interest as potential therapeutic agents. As the discovery of new AMPs has increased, many databases specializing in AMPs have been developed to collect both fundamental and pharmacological information. In this review, we summarize the sources, structures, modes of action, and classifications of AMPs. Additionally, we examine current AMP databases, compare valuable computational tools used to predict antimicrobial activity and mechanisms of action, and highlight new machine learning approaches that can be employed to improve AMP activity to combat global antimicrobial resistance.
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Cited by
Antimicrobial peptides: Structure, mechanism, and modification
Chen, N., & Jiang, C. (2023) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2023.115377 · Cited by 279
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Antimicrobial peptides for bone tissue engineering: Diversity, effects and applications
Hao, Z., Chen, R., Chai, C., Wang, Y., Chen, T., Li, H., Hu, Y., Feng, Q., & Li, J. (2022) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2022.1030162 · Cited by 47
Azadi, S., Yazdanpanah, M. A., Afshari, A., Alahdad, N., Chegeni, S., Angaji, A., Rezayat, S. M., & Tavakol, S. (2024) · Journal of Tissue Engineering · doi:10.1177/20417314241303818 · Cited by 24
Metadata
- Authors
- Bin Hafeez, A., Jiang, X., Bergen, P. J., & Zhu, Y.
- Venue
- International Journal of Molecular Sciences
- Publisher
- MDPI AG
- Published
- 2021-10-28
- Volume
- 22
- Issue
- 21
- Pages
- 11691
- ISSN
- 1422-0067 (ISSN-L)
- OpenAlex
- W3210497502
- Cited by
- 341
- References
- 529
- FWCI
- 26.84
- Type
- journal article
- Language
- en
- Open access
- gold
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- Bin Hafeez, A., Jiang, X., Bergen, P. J., & Zhu, Y. (2021). Antimicrobial Peptides: An Update on Classifications and Databases. International Journal of Molecular Sciences. https://doi.org/10.3390/ijms222111691
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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