The DOI matches its Crossref record; 120 of the 120 references it cites were found in a registry or an index.
Non-Alcoholic Fatty Liver Disease (NAFLD) Pathogenesis and Natural Products for Prevention and Treatment
Open accessAbstract
Non-alcoholic fatty liver disease (NAFLD) is the most prevalent chronic liver disease, affecting approximately one-quarter of the global population, and has become a world public health issue. NAFLD is a clinicopathological syndrome characterized by hepatic steatosis, excluding ethanol and other definite liver damage factors. Recent studies have shown that the development of NAFLD is associated with lipid accumulation, oxidative stress, endoplasmic reticulum stress, and lipotoxicity. A range of natural products have been reported as regulators of NAFLD in vivo and in vitro. This paper reviews the pathogenesis of NAFLD and some natural products that have been shown to have therapeutic effects on NAFLD. Our work shows that natural products can be a potential therapeutic option for NAFLD.
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1 retracted
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RetractedYounossi, Z. M., Koenig, A. B., Abdelatif, D., Fazel, Y., Henry, L., & Wymer, M. (2016) · Hepatology · doi:10.1002/hep.28431 · Cited by 10,781
Membrane lipids: where they are and how they behave
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Global burden of NAFLD and NASH: trends, predictions, risk factors and prevention
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Endoplasmic Reticulum Stress Links Obesity, Insulin Action, and Type 2 Diabetes
Özcan, U., Cao, Q., Yilmaz, E., Lee, A.-H., Iwakoshi, N. N., Özdelen, E., Tuncman, G., Görgün, C., Glimcher, L. H., & Hotamisligil, G. S. (2004) · Science · doi:10.1126/science.1103160 · Cited by 3,844
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Current status and future trends of the global burden of MASLD
Miao, L., Targher, G., Byrne, C. D., Cao, Y.-Y., & Zheng, M.-H. (2024) · Trends in Endocrinology & Metabolism · doi:10.1016/j.tem.2024.02.007 · Cited by 781
Benedé-Ubieto, R., Cubero, F. J., & Nevzorova, Y. A. (2024) · Gut Microbes · doi:10.1080/19490976.2024.2331460 · Cited by 242
Shrestha, S., Jeon, J.-H., & Hong, C.-W. (2025) · BMB Reports · doi:10.5483/bmbrep.2024-0058 · Cited by 30
Varmazyar, I., Monazzami, A. A., Moradi, M., & McAinch, A. J. (2024) · BMC Sports Science, Medicine and Rehabilitation · doi:10.1186/s13102-024-00972-9 · Cited by 7
PKM2 Drives Lactate-mediated Fibrosis in Liver Transplantation
Liu, J.-Y., Liao, W., Chen, Z.-Y., Liu, T., Wang, R., Gong, J.-P., Xu, X.-S., & Wu, H. (2025) · Transplantation · doi:10.1097/tp.0000000000005461 · Cited by 6
Metadata
- Authors
- Guo, X., Yin, X., Liu, Z., & Wang, J.
- Venue
- International Journal of Molecular Sciences
- Publisher
- MDPI AG
- Published
- 2022-12-07
- Volume
- 23
- Issue
- 24
- Pages
- 15489
- ISSN
- 1422-0067 (ISSN-L)
- OpenAlex
- W4311730330
- Cited by
- 412
- References
- 120
- FWCI
- 48.53
- Type
- journal article
- Language
- en
- Open access
- gold
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- Guo, X., Yin, X., Liu, Z., & Wang, J. (2022). Non-Alcoholic Fatty Liver Disease (NAFLD) Pathogenesis and Natural Products for Prevention and Treatment. International Journal of Molecular Sciences. https://doi.org/10.3390/ijms232415489
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
