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Cited by 8Obsessive-Compulsive Spectrum DisordersAnxiety, Depression, Psychometrics, Treatment, Cognitive ProcessesPsychoanalysis and Psychopathology Research

Cognitive–Behavioral Treatment of Obsessive–Compulsive Disorder: The Results of a Naturalistic Outcomes Study

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Gragnani, Andrea, Zaccari, Vittoria, Femia, Giuseppe, Pellegrini, Valerio, Tenore, Katia, Fadda, Stefania, Luppino, Olga, Basile, Barbara +5 more·2022·Journal of Clinical Medicine
DOI 10.3390/jcm11102762PMC PMC9145175
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Abstract

Cognitive−behavioral therapy is a well-established treatment for obsessive−compulsive disorder (OCD). There are a variety of cognitive and behavioral strategies, and it is necessary to analyze the outcomes of the treatments. The aim of the present study is to verify the effectiveness of a treatment that combines evidence-based procedures and specific cognitive interventions highlighting the issue of acceptance. Forty patients with OCD were recruited and underwent a specific treatment procedure. All patients had a psychodiagnostic assessment for OCD using the Y−BOCS (Yale−Brown obsessive−compulsive scale) performed twice: before treatment (t0) and after nine months (t1). Data analysis showed a decrease in the scores between t0 and t1 according to the Y−BOCS in terms of the interference, severity, and impairment of obsessive−compulsive symptoms. A repeated-measures ANOVA showed a significant reduction in symptoms after treatment, with values of F (1, 39) = 137.56, p < 0.001, and η2 = 0.78. The ANOVA results were corroborated by a Wilcoxon signed-rank test. A reliable change index analysis indicated that 33 participants reported improvements in symptoms, of which 23 were clinically significant. The results showed clinical relevance for OCD treatment and highlighted how this cognitive procedure favored positive outcomes.

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  • Only a few studies have examined the effectiveness of interventions targeting moral self-criticism and guilt.

    “Despite the growing amount of research showing the existence of a close link between self-criticism, guilt, and OCD, only a few studies have examined the effectiveness of interventions targeting moral self-criticism and guilt (Cosentino et al., 2012; Gragnani et al., 2022; Perdighe & Mancini, 2012; Petrocchi et al., 2021; Tenore et al., 2020).”

    From TREATING GUILT-INDUCING SELF-TALK IN OCD WITH DRAMATIZED SOCRATIC DIALOGUE: A STEP BY STEP INTERVENTION (2024) · cites this paper as Gragnani et al., 2022

    The Treatment section describes techniques intended to reduce guilt, and the Results assess the effectiveness of the overall CBT treatment for OCD. The paper does not establish that only a few studies have examined such interventions, and its Discussion says self-criticism was not measured as an outcome. (LLM, conf=0.86)

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Authors
Gragnani, A., Zaccari, V., Femia, G., Pellegrini, V., Tenore, K., Fadda, S., Luppino, O., Basile, B., Cosentino, T., Perdighe, C., Romano, G., Saliani, A., & Mancini, F.
Affiliations
  • Associazione Scuola di Psicoterapia Cognitiva (APC-SPC), 00185 Rome, Italy
  • Marconi University (IT)
  • Sapienza University of Rome (IT)
Corresponding author
  • Gragnani, Andrea
  • Zaccari, Vittoria
ORCID
Venue
Journal of Clinical Medicine
Publisher
MDPI AG
Published
2022-05-13
Volume
11
Issue
10
Pages
2762
ISSN
2077-0383 (ISSN-L)
DOI
10.3390/jcm11102762
PMC
PMC9145175
OpenAlex
W4280519097
Cited by
8
References
16
Citations by year
2025: 4 · 2024: 2 · 2023: 2
FWCI
1.83
Type
journal article
Language
en
Open access
Licence
Locations
  • Journal of Clinical Medicine (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • IRIS Research product catalog (Sapienza University of Rome) (submittedVersion, cc-by)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
Topics
  • Social Sciences › Psychology › Clinical Psychology › Obsessive-Compulsive Spectrum Disorders
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
  • Social Sciences › Psychology › Clinical Psychology › Psychoanalysis and Psychopathology Research
Keywords
obsessive-compulsive disorder, cognitive behavioral therapy, treatment outcomes, Yale-Brown Obsessive Compulsive Scale, symptom relief, acceptance, treatment effectiveness, clinical significance

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