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Cited by 6Gestational Diabetes Research and ManagementDiabetes, Cardiovascular Risks, and LipoproteinsPregnancy and preeclampsia studies

Metabolic syndrome prevalence in women with gestational diabetes mellitus in the second trimester of gravidity

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Bartáková, Vendula, Chalásová, Katarína, Pácal, Lukáš, Ťápalová, Veronika, Máchal, Jan, Janků, Petr, Kaňková, Kateřina·2024·Journal of Clinical Medicine
DOI 10.3390/jcm13051260PMC PMC10932344
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Abstract

Background: Women with gestational diabetes (GDM) have an increased risk of metabolic syndrome (MS) after delivery. MS could precede gravidity. The aims of this study were (i) to detect the prevalence of MS in women at the time of GDM diagnosis, (ii) to detect the prevalence of MS in the subgroup of GDM patients with any form of impaired glucose tolerance after delivery (PGI), and (iii) to determine whether GDM women with MS have a higher risk of peripartal adverse outcomes. Methods: A cross-sectional observational study comprised n = 455 women with GDM. International Diabetes Federation (IDF) criteria for MS definition were modified to the pregnancy situation. Results: MS was detected in 22.6% of GDM patients in those with PGI 40%. The presence of MS in GDM patients was associated with two peripartal outcomes: higher incidence of pathologic Apgar score and macrosomia (p = 0.01 resp. p = 0.0004, chi-square). Conclusions: The presence of MS in GDM patients is a statistically significant risk factor (p = 0.04 chi-square) for PGI. A strong clinical implication of our findings might be to include MS diagnostics within GDM screening using modified MS criteria in the second trimester of pregnancy.

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  • Metabolic syndrome has been very prevalent among women who have gestational diabetes mellitus, especially in the second trimester of pregnancy.

    “Metabolic syndrome has also been very prevalent among women who have GDM, especially in the second trimester of pregnancy (12).”

    From Maternal nutritional status and the risk of metabolic syndrome in pregnancy: implications for public health nutrition (2026) · cites this paper as [12]

    The Results (§3.1; page unavailable) report metabolic syndrome in 22.6% of women with GDM at 24–28 weeks of pregnancy. The paper studied prevalence in the second trimester but did not compare trimesters, so it does not establish that prevalence is especially high then. (LLM, conf=0.84)

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Cited by

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Authors
Bartáková, V., Chalásová, K., Pácal, L., Ťápalová, V., Máchal, J., Janků, P., & Kaňková, K.
Affiliations
  • Masaryk University (CZ)
  • University Hospital Brno (CZ)
Corresponding author
Bartáková, Vendula
ORCID
Venue
Journal of Clinical Medicine
Publisher
MDPI AG
Published
2024-02-22
Volume
13
Issue
5
Pages
1260
ISSN
2077-0383 (ISSN-L)
DOI
10.3390/jcm13051260
PMC
PMC10932344
OpenAlex
W4392058720
Cited by
6
References
3
Citations by year
2026: 1 · 2025: 5
FWCI
3.32
Type
journal article
Language
en
Open access
Licence
Locations
  • Journal of Clinical Medicine (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • Veřejné služby Informačního systému (Masarykiana Brunensis Universitas) (submittedVersion, cc-by)
Funders
European Union—Next-Generation EU (LX22NPO5104)
Topics
  • Health Sciences › Medicine › Obstetrics and Gynecology › Gestational Diabetes Research and Management
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
  • Health Sciences › Medicine › Obstetrics and Gynecology › Pregnancy and preeclampsia studies
Keywords
metabolic syndrome, gestational diabetes mellitus, second trimester, macrosomia, Apgar score, metabolic syndrome screening, women

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