The DOI matches its Crossref record; 31 of the 32 references it cites were found in a registry or an index.
Postoperative Surveillance in the Postoperative vs. Intensive Care Unit for Patients Undergoing Elective Supratentorial Brain Tumor Removal: A Retrospective Observational Study
Open accessAbstract
Background: Recent evidence suggests that alternative postoperative surveillance approaches for patients undergoing elective neurosurgical procedures are less resource-intensive and result in similar or fewer complications compared to high-care settings such as Intensive Care Units (ICUs). A new postoperative care protocol was established at our facility including routine PACU admission and predefined criteria for ICU admission. We aimed to demonstrate that PACU admission is a safe option for patients undergoing elective craniotomy following eventless surgery. Methods: This retrospective analysis included patients undergoing elective supratentorial craniotomy before and after the implementation of the new protocol. Patients with surgery between January 2020 and January 2022 and routine ICU admission were compared to patients undergoing surgery between February 2022 and March 2023 with either PACU or ICU admission based on the new protocol regarding lengths of hospital stay (LOSs), costs, and complications. Results: Data from a total of 405 patients, 198 patients before and 209 patients after the protocol implementation, were included. Both groups were comparable regarding demographics, American Society of Anesthesiologists (ASA) physical status classification, preexisting health conditions, and tumor entity and volume. Postoperative LOSs were significantly shorter in PACU compared to ICU patients of the same cohort (6 d vs. 11 d, p = 0.002). Patients with postoperative PACU transfer suffered fewer intracranial infections, surgical site infections, and pneumonia occurrences. Surgery-related complications, 30- and 90-day readmissions, and mortality rates were comparable in both groups. Conclusions: Postoperative PACU admission is a safe and viable option for patients undergoing elective craniotomy when selection is thorough and is associated with fewer ICU-related complications.
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“whereas underestimation poses a direct risk to patients [7].”
From Prediction of Postoperative ICU Requirements: Closing the Translational Gap with a Real-World Clinical Benchmark for Artificial Intelligence Approaches (2025) · cites this paper as [7]
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Health Care–Associated Infections
Zimlichman, E., Henderson, D., Tamir, O., Franz, C., Song, P., Yamin, C. K., Keohane, C. A., Denham, C. R., & Bates, D. W. (2013) · JAMA Internal Medicine · doi:10.1001/jamainternmed.2013.9763 · Cited by 1,927
World Medical Association (2025) · JAMA · doi:10.1001/jama.2024.21972 · Cited by 1,695
Blot, S. I., Ruppé, É., Harbarth, S., Asehnoune, K., Poulakou, G., Luyt, C. E., Rello, J., Klompas, M., Depuydt, P. O., Eckmann, C., et al. (2022) · Intensive and Critical Care Nursing · doi:10.1016/j.iccn.2022.103227 · Cited by 389
Underresourced Hospital Infection Control and Prevention Programs: Penny Wise, Pound Foolish?
Anderson, D. J., Kirkland, K. B., Kaye, K. S., Thacker, P. A., Kanafani, Z. A., Auten, G., & Sexton, D. J. (2007) · Infection Control and Hospital Epidemiology · doi:10.1086/518518 · Cited by 188
Impact of healthcare-associated infection on length of stay
Stewart, S., Robertson, C., Pan, J., Kennedy, S., Haahr, L., Manoukian, S., Mason, H., Kavanagh, K., Graves, N., Dancer, S. J., et al. (2021) · Journal of Hospital Infection · doi:10.1016/j.jhin.2021.02.026 · Cited by 162
Postoperative complications after craniotomy for brain tumor surgery
Lonjaret, L., Guyonnet, M., Bérard, E., Vironneau, M., Peres, F., Sacrista, S., Ferrier, A., Ramonda, V., Vuillaume, C., Roux, F., et al. (2016) · Anaesthesia Critical Care & Pain Medicine · doi:10.1016/j.accpm.2016.06.012 · Cited by 138
Outpatient Craniotomy for Brain Tumor: A Pilot Feasibility Study in 46 Patients
Bernstein, M. (2001) · Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques · doi:10.1017/s0317167100052781 · Cited by 119
Enhanced Recovery After Surgery strategies for elective craniotomy: a systematic review
Stumpo, V., Staartjes, V. E., Quddusi, A. I., Corniola, M. V., Tessitore, E., Schröder, M. L., Anderer, E. G., Stienen, M. N., Serra, C., & Regli, L. (2021) · Journal of neurosurgery · doi:10.3171/2020.10.jns203160 · Cited by 116
Postoperative Intensive Care Unit Requirements After Elective Craniotomy
Hanak, B. W., Walcott, B. P., Nahed, B. V., Muzikansky, A., Mian, M. K., Kimberly, W. T., & Curry, W. T. (2012) · World Neurosurgery · doi:10.1016/j.wneu.2012.11.068 · Cited by 102
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Sbaih, O. I., Singh, A. K., Li, A. Y., Kolady, R., Patel, A. K., Jay, C., Silberstein, H. J., & LoPresti, M. A. (2025) · Journal of Neuro-Oncology · doi:10.1007/s11060-025-05354-w · Cited by 1
Althammer, A., Berger, F., Spring, O., Simon, P., Girrbach, F., Dieing, M., Brunner, J. O., Shmygalev, S., Bartenschlager, C. C., & Heller, A. R. (2025) · Information · doi:10.3390/info16100888
Self-citationPulmonary Embolism Complicating an Extended Postanesthesia Care Unit Stay: A Case Report
Suliman, M., Amara, U. E., Nashrah, U., & Shaikh, N. (2026) · Cureus · doi:10.7759/cureus.115203
Metadata
- Authors
- Nothofer, S., Geipel, J., Aehling, K., Sommer, B., Heller, A. R., Shiban, E., & Simon, P.
- Affiliations
- University of Augsburg (DE)
- Medizinische Universität Lausitz - Carl Thiem (DE)
- Corresponding author
- Simon, Philipp
- Venue
- Journal of Clinical Medicine
- Publisher
- MDPI AG
- Published
- 2025-04-11
- Volume
- 14
- Issue
- 8
- Pages
- 2632
- ISSN
- 2077-0383 (ISSN-L)
- PMC
- PMC12027877
- OpenAlex
- W4409348449
- Cited by
- 3
- References
- 31
- Citations by year
- 2026: 1 · 2025: 2
- FWCI
- 2.82
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Journal of Clinical Medicine (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Surgery › Enhanced Recovery After Surgery
- Health Sciences › Medicine › Clinical Neurology › Neurosurgical Procedures and Complications
- Health Sciences › Medicine › Critical Care and Intensive Care Medicine › Intensive Care Unit Cognitive Disorders
- Keywords
- postoperative care, post-anesthesia care unit, intensive care unit admission, elective craniotomy, length of hospital stay, postoperative complications, surgical site infection, intracranial infection, pneumonia, hospital readmission, health care costs, elective neurosurgery
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- Nothofer, S., Geipel, J., Aehling, K., Sommer, B., Heller, A. R., Shiban, E., & Simon, P. (2025). Postoperative Surveillance in the Postoperative vs. Intensive Care Unit for Patients Undergoing Elective Supratentorial Brain Tumor Removal: A Retrospective Observational Study. Journal of Clinical Medicine. https://doi.org/10.3390/jcm14082632
