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Cited by 38Origins and Evolution of LifeRNA and protein synthesis mechanismsOrganophosphorus compounds synthesis

Potential Role of Inorganic Confined Environments in Prebiotic Phosphorylation

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Dass, Avinash, Jaber, Maguy, Brack, André, Foucher, Frédéric, Kee, Terence, Georgelin, Thomas, Westall, Frances·2018·Life
DOI 10.3390/life8010007PMC PMC5871939
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Abstract

A concise outlook on the potential role of confinement in phosphorylation and phosphate condensation pertaining to prebiotic chemistry is presented. Inorganic confinement is a relatively uncharted domain in studies concerning prebiotic chemistry, and even more so in terms of experimentation. However, molecular crowding within confined dimensions is central to the functioning of contemporary biology. There are numerous advantages to confined environments and an attempt to highlight this fact, within this article, has been undertaken, keeping in context the limitations of aqueous phase chemistry in phosphorylation and, to a certain extent, traditional approaches in prebiotic chemistry.

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  • Concentration or 'crowding' of organic molecules is an important aspect of prebiotic chemistry.

    “Since concentration or 'crowding' of organic molecules is an important aspect of prebiotic chemistry, molecules disseminated or dissolved in fluids could also be concentrated by the mineral surfaces (Dass et al. 2016(Dass et al. , 2018;;Westall et al. 2018).”

    From The Emergence of Life (2019) · cites this paper as Dass et al. 2018

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Cited by

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Authors
Dass, A., Jaber, M., Brack, A., Foucher, F., Kee, T., Georgelin, T., & Westall, F.
Affiliations
  • Centre National de la Recherche Scientifique (FR)
  • University of Leeds (GB)
  • Centre de Biophysique Moléculaire (CBM), Centre National de la Recherche Scientifique (CNRS), Rue Charles Sadron, 45071 Orléans, France
Corresponding author
Georgelin, Thomas
ORCID
Venue
Life
Publisher
MDPI AG
Published
2018-03-05
Volume
8
Issue
1
Pages
7
ISSN
2075-1729 (ISSN-L)
DOI
10.3390/life8010007
PMC
PMC5871939
OpenAlex
W2792032237
Cited by
38
References
7
Citations by year
2026: 1 · 2025: 1 · 2024: 5 · 2023: 5 · 2022: 8 · 2021: 5 · 2020: 5 · 2019: 4 · 2018: 4
FWCI
2.41
Type
journal article
Language
en
Open access
Licence
Locations
  • Life (publishedVersion, cc-by)
  • Europe PMC (PubMed Central) (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • White Rose Research Online (University of Leeds, The University of Sheffield, University of York) (acceptedVersion)
  • HAL (submittedVersion, cc-by)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Topics
  • Physical Sciences › Physics and Astronomy › Astronomy and Astrophysics › Origins and Evolution of Life
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › RNA and protein synthesis mechanisms
  • Physical Sciences › Chemistry › Organic Chemistry › Organophosphorus compounds synthesis
Keywords
confined spaces, macromolecular crowding, prebiotic chemistry, origin of life

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