The DOI matches its Crossref record; 107 of the 107 references it cites were found in a registry or an index.
Superparamagnetic Iron Oxide Nanoparticles—Current and Prospective Medical Applications
Open accessAbstract
The recent, fast development of nanotechnology is reflected in the medical sciences. Superparamagnetic Iron Oxide Nanoparticles (SPIONs) are an excellent example. Thanks to their superparamagnetic properties, SPIONs have found application in Magnetic Resonance Imaging (MRI) and magnetic hyperthermia. Unlike bulk iron, SPIONs do not have remnant magnetization in the absence of the external magnetic field; therefore, a precise remote control over their action is possible. This makes them also useful as a component of the advanced drug delivery systems. Due to their easy synthesis, biocompatibility, multifunctionality, and possibility of further surface modification with various chemical agents, SPIONs could support many fields of medicine. SPIONs have also some disadvantages, such as their high uptake by macrophages. Nevertheless, based on the ongoing studies, they seem to be very promising in oncological therapy (especially in the brain, breast, prostate, and pancreatic tumors). The main goal of our paper is, therefore, to present the basic properties of SPIONs, to discuss their current role in medicine, and to review their applications in order to inspire future developments of new, improved SPION systems.
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Cited by
Magnetic Resonance Imaging and Iron-oxide Nanoparticles in the era of Personalized Medicine
Rahman, M. (2023) · Nanotheranostics · doi:10.7150/ntno.86467 · Cited by 244
Vasić, K., Knez, Ž., & Leitgeb, M. (2024) · Journal of Functional Biomaterials · doi:10.3390/jfb15080227 · Cited by 76
A Promising Approach: Magnetic Nanosystems for Alzheimer’s Disease Theranostics
Chaparro, C. I. P., Simões, B. T., Borges, J. P., Castanho, M. A. R. B., Soares, P. I. P., & Neves, V. (2023) · Pharmaceutics · doi:10.3390/pharmaceutics15092316 · Cited by 40
Metadata
- Authors
- Dulińska-Litewka, J., Łazarczyk, A., Hałubiec, P., Szafrański, O., Karnas, K., & Karewicz, A.
- Venue
- Materials
- Publisher
- MDPI AG
- Published
- 2019-02-19
- Volume
- 12
- Issue
- 4
- Pages
- 617
- ISSN
- 1996-1944 (ISSN-L)
- OpenAlex
- W2913935491
- Cited by
- 580
- References
- 107
- FWCI
- 23.55
- Type
- journal article
- Language
- en
- Open access
- gold
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- Dulińska-Litewka, J., Łazarczyk, A., Hałubiec, P., Szafrański, O., Karnas, K., & Karewicz, A. (2019). Superparamagnetic Iron Oxide Nanoparticles—Current and Prospective Medical Applications. Materials. https://doi.org/10.3390/ma12040617
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
