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The Toxic Effects and Mechanisms of CuO and ZnO Nanoparticles
Open accessAbstract
Recent nanotechnological advances suggest that metal oxide nanoparticles (NPs) have been expected to be used in various fields, ranging from catalysis and opto-electronic materials to sensors, environmental remediation, and biomedicine. However, the growing use of NPs has led to their release into environment and the toxicity of metal oxide NPs on organisms has become a concern to both the public and scientists. Unfortunately, there are still widespread controversies and ambiguities with respect to the toxic effects and mechanisms of metal oxide NPs. Comprehensive understanding of their toxic effect is necessary to safely expand their use. In this review, we use CuO and ZnO NPs as examples to discuss how key factors such as size, surface characteristics, dissolution, and exposure routes mediate toxic effects, and we describe corresponding mechanisms, including oxidative stress, coordination effects and non-homeostasis effects.
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Laurent, S., Forge, D., Port, M., Roch, A., Robic, C., Vander Elst, L., & Muller, R. N. (2008) · Chemical Reviews · doi:10.1021/cr068445e · Cited by 6,852
Evidence for stripe correlations of spins and holes in copper oxide superconductors
Tranquada, J. M., Sternlieb, B. J., Axe, J. D., Nakamura, Y., & Uchida, S. (1995) · Nature · doi:10.1038/375561a0 · Cited by 3,144
Brunner, T. J., Wick, P., Manser, P., Spohn, P., Grass, R. N., Limbach, L. K., Bruinink, A., & Stark, W. J. (2006) · Environmental Science & Technology · doi:10.1021/es052069i · Cited by 1,385
Size-dependent toxicity of metal oxide particles—A comparison between nano- and micrometer size
Karlsson, H. L., Gustafsson, J., Cronholm, P., & Möller, L. (2009) · Toxicology Letters · doi:10.1016/j.toxlet.2009.03.014 · Cited by 949
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Methods of Synthesis, Properties and Biomedical Applications of CuO Nanoparticles
Grigore, M., Biscu, E., Holban, A., Gestal, M., & Grumezescu, A. (2016) · Pharmaceuticals · doi:10.3390/ph9040075 · Cited by 445
Antibacterial Activity of TiO2- and ZnO-Decorated with Silver Nanoparticles
Nguyen, V., Vu, V., Nguyen, T., Nguyen, T., Tran, V., & Nguyen-Tri, P. (2019) · Journal of Composites Science · doi:10.3390/jcs3020061 · Cited by 144
Nazarizadeh, A., & Asri-Rezaie, S. (2016) · AAPS PharmSciTech · doi:10.1208/s12249-015-0405-y · Cited by 135
Synthesis, characterization and cytotoxicity of zinc oxide nanoparticles by green synthesis method
Patrón-Romero, L., Luque, P. A., Soto-Robles, C. A., Nava, O., Vilchis-Nestor, A. R., Barajas-Carrillo, V. W., Martínez-Ramírez, C. E., Chávez Méndez, J. R., Alvelais Palacios, J. A., Leal Ávila, M. Á., et al. (2020) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2020.101925 · Cited by 33
Metadata
- Authors
- Chang, Y.-N., Zhang, M., Xia, L., Zhang, J., & Xing, G.
- Venue
- Materials
- Publisher
- MDPI AG
- Published
- 2012-12-13
- Volume
- 5
- Issue
- 12
- Pages
- 2850-2871
- ISSN
- 1996-1944 (ISSN-L)
- OpenAlex
- W2105922265
- Cited by
- 772
- References
- 4
- FWCI
- 12.02
- Type
- journal article
- Language
- en
- Open access
- gold
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