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The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.

The Toxic Effects and Mechanisms of CuO and ZnO Nanoparticles

Open access
Chang, Ya-Nan, Zhang, Mingyi, Xia, Lin, Zhang, Jun, Xing, Gengmei·2012·Materials

Abstract

Recent nanotechnological advances suggest that metal oxide nanoparticles (NPs) have been expected to be used in various fields, ranging from catalysis and opto-electronic materials to sensors, environmental remediation, and biomedicine. However, the growing use of NPs has led to their release into environment and the toxicity of metal oxide NPs on organisms has become a concern to both the public and scientists. Unfortunately, there are still widespread controversies and ambiguities with respect to the toxic effects and mechanisms of metal oxide NPs. Comprehensive understanding of their toxic effect is necessary to safely expand their use. In this review, we use CuO and ZnO NPs as examples to discuss how key factors such as size, surface characteristics, dissolution, and exposure routes mediate toxic effects, and we describe corresponding mechanisms, including oxidative stress, coordination effects and non-homeostasis effects.

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Metadata

Authors
Chang, Y.-N., Zhang, M., Xia, L., Zhang, J., & Xing, G.
Venue
Materials
Publisher
MDPI AG
Published
2012-12-13
Volume
5
Issue
12
Pages
2850-2871
ISSN
1996-1944 (ISSN-L)
OpenAlex
W2105922265
Cited by
772
References
4
FWCI
12.02
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: The Toxic Effects and Mechanisms of CuO and ZnO Nanoparticles. https://app.cochat.ai/papers/10.3390/ma5122850
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Chang, Y.-N., Zhang, M., Xia, L., Zhang, J., & Xing, G. (2012). The Toxic Effects and Mechanisms of CuO and ZnO Nanoparticles. Materials. https://doi.org/10.3390/ma5122850

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.