The DOI matches its Crossref record; 137 of the 137 references it cites were found in a registry or an index.
A Review of Applications of Metabolomics in Cancer
Open accessAbstract
Cancer is a devastating disease that alters the metabolism of a cell and the surrounding milieu. Metabolomics is a growing and powerful technology capable of detecting hundreds to thousands of metabolites in tissues and biofluids. The recent advances in metabolomics technologies have enabled a deeper investigation into the metabolism of cancer and a better understanding of how cancer cells use glycolysis, known as the “Warburg effect,” advantageously to produce the amino acids, nucleotides and lipids necessary for tumor proliferation and vascularization. Currently, metabolomics research is being used to discover diagnostic cancer biomarkers in the clinic, to better understand its complex heterogeneous nature, to discover pathways involved in cancer that could be used for new targets and to monitor metabolic biomarkers during therapeutic intervention. These metabolomics approaches may also provide clues to personalized cancer treatments by providing useful information to the clinician about the cancer patient’s response to medical interventions.
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Cites
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Self-citationWhy Do Cancers Have High Aerobic Glycolysis?
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Precision medicine and radiogenomics in breast cancer: new approaches toward diagnosis and treatment
Pinker, K., Chin, J., Melsaether, A. N., Morris, E. A., & Moy, L. (2018) · Radiology · doi:10.1148/radiol.2018172171 · Cited by 275
Recent advances in microfluidic methods in cancer liquid biopsy
Iliescu, F. S., Poenar, D. P., Yu, F., Ni, M., Chan, K. H., Cima, I., Taylor, H. K., Cima, I., & Iliescu, C. (2019) · Biomicrofluidics · doi:10.1063/1.5087690 · Cited by 51
The Potential Role of Metabolomics in Drug-Induced Liver Injury (DILI) Assessment
Moreno-Torres, M., Quintás, G., & Castell, J. V. (2022) · Metabolites · doi:10.3390/metabo12060564 · Cited by 50
Alterations in the gastric microbiota and metabolites in gastric cancer: An update review
Lei, C., Gong, D., Zhuang, B., & Zhang, Z. (2022) · Frontiers in Oncology · doi:10.3389/fonc.2022.960281 · Cited by 20
Metadata
- Authors
- Beger, R.
- Venue
- Metabolites
- Publisher
- MDPI AG
- Published
- 2013-07-05
- Volume
- 3
- Issue
- 3
- Pages
- 552-574
- ISSN
- 2218-1989 (ISSN-L)
- OpenAlex
- W2065342065
- Cited by
- 288
- References
- 137
- FWCI
- 6.05
- Type
- journal article
- Language
- en
- Open access
- gold
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