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Cited by 279

The DOI matches its Crossref record; 174 of the 174 references it cites were found in a registry or an index.

Molecular Mechanism Underlying Anti-Inflammatory and Anti-Allergic Activities of Phytochemicals: An Update

Open access
Bellik, Yuva, Boukraâ, Laïd, Alzahrani, Hasan, Bakhotmah, Balkees, Abdellah, Fatiha, Hammoudi, Si, Iguer-Ouada, Mokrane·2012·Molecules
DOI 10.3390/molecules18010322
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Abstract

The resort worldwide to edible medicinal plants for medical care has increased significantly during the last few years. Currently, there is a renewed interest in the search for new phytochemicals that could be developed as useful anti-inflammatory and anti-allergic agents to reduce the risk of many diseases. The activation of nuclear transcription factor-kappa B (NF-κB) has now been linked to a variety of inflammatory diseases, while data from numerous studies underline the importance of phytochemicals in inhibiting the pathway that activates this transcription factor. Moreover, the incidence of type I allergic disorders has been increasing worldwide, particularly, the hypersensitivity to food. Thus, a good number of plant products with anti-inflammatory and anti-allergic activity have been documented, but very few of these compounds have reached clinical use and there is scant scientific evidence that could explain their mode of action. Therefore, this paper intends to review the most salient recent reports on the anti-inflammatory and anti-allergic properties of phytochemicals and the molecular mechanisms underlying these properties.

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Metadata

Authors
Bellik, Y., Boukraâ, L., Alzahrani, H., Bakhotmah, B., Abdellah, F., Hammoudi, S., & Iguer-Ouada, M.
Venue
Molecules
Publisher
MDPI AG
Published
2012-12-27
Volume
18
Issue
1
Pages
322-353
ISSN
1420-3049 (ISSN-L)
DOI
10.3390/molecules18010322
OpenAlex
W2071071686
Cited by
279
References
174
FWCI
23.59
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: Molecular Mechanism Underlying Anti-Inflammatory and Anti-Allergic Activities of Phytochemicals: An Update. https://app.cochat.ai/papers/10.3390/molecules18010322
The paper
Bellik, Y., Boukraâ, L., Alzahrani, H., Bakhotmah, B., Abdellah, F., Hammoudi, S., & Iguer-Ouada, M. (2012). Molecular Mechanism Underlying Anti-Inflammatory and Anti-Allergic Activities of Phytochemicals: An Update. Molecules. https://doi.org/10.3390/molecules18010322

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