Cited by 783Bee Products Chemical AnalysisHealthcare and Venom ResearchPhytochemistry and Biological Activities

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Recent Advances in the Chemical Composition of Propolis

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Huang, Shuai, Zhang, Cui-Ping, Wang, Kai, Li, George, Hu, Fu-Liang·2014·Molecules

DOI 10.3390/molecules191219610PMC PMC6271758

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Abstract

Propolis is a honeybee product with broad clinical applications. Current literature describes that propolis is collected from plant resins. From a systematic database search, 241 compounds were identified in propolis for the first time between 2000 and 2012; and they belong to such diverse chemical classes as flavonoids, phenylpropanoids, terpenenes, stilbenes, lignans, coumarins, and their prenylated derivatives, showing a pattern consistent with around 300 previously reported compounds. The chemical characteristics of propolis are linked to the diversity of geographical location, plant sources and bee species.

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Authors: Huang, S., Zhang, C.-P., Wang, K., Li, G., & Hu, F.-L.
Affiliations: Zhejiang University (CN)
College of Animal Sciences, Zhejiang University, Hangzhou 310058, China
The University of Sydney (AU)
Corresponding author: Li, George
ORCID: Huang, Shuai
Wang, Kai
Li, George
Venue: Molecules
Publisher: MDPI AG
Published: 2014-11-26
Volume: 19
Issue: 12
Pages: 19610-19632
ISSN: 1420-3049 (ISSN-L)
DOI: 10.3390/molecules191219610
PMC: PMC6271758
OpenAlex: W2040270316
Cited by: 765
References: 105
Citations by year: 2026: 40 · 2025: 81 · 2024: 85 · 2023: 93 · 2022: 82 · 2021: 98 · 2020: 69 · 2019: 80 · 2018: 51 · 2017: 46 · 2016: 31 · 2015: 8
FWCI: 3.74
Type: journal article
Language: en
Open access: gold
dx.doi.org
Licence: cc-by
creativecommons.org/licenses/by/4.0/ (vor)
Locations: Molecules (publishedVersion, cc-by)
Europe PMC (PubMed Central) (publishedVersion, cc-by)
PubMed Central (publishedVersion, cc-by)
PubMed (publishedVersion)
DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Minerva Access (University of Melbourne) (submittedVersion, cc-by)
Funders: National Natural Science Foundation of China (CARS-45, 31272512)
Earmarked Fund for Modern Agro-industry Technology Research System (31272512, CARS-45)
Topics: Life Sciences › Agricultural and Biological Sciences › Insect Science › Bee Products Chemical Analysis
Health Sciences › Medicine › Pharmacology (medical) › Healthcare and Venom Research
Life Sciences › Agricultural and Biological Sciences › Plant Science › Phytochemistry and Biological Activities
Keywords: propolis, chemical composition, flavonoids, phenylpropanoids, terpenes, stilbenes, lignans, coumarins, honey bee products, regional variation, plant sources, bee species
MeSH terms: Animals, Bees, Elements, Geography, Organic Chemicals, Plants, Propolis

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