The DOI matches its Crossref record; 26 of the 26 references it cites were found in a registry or an index.
Chloro-1,4-dimethyl-9H-carbazole Derivatives Displaying Anti-HIV Activity
Open accessAbstract
Background: Despite the progress achieved by anti-retroviral drug research in the last decades, the discovery of novel compounds endowed with selective antiviral activity and reduced side effects is still a necessity. At present, the most urgent requirement includes the improvement of HIV (Human Immunodeficiency Virus) prevention and sexual transmission and the development of new drugs to treat the chronic lifelong infection. Methods: Six chloro-1,4-dimethyl-9H-carbazoles (2a,b–4a,b) have been prepared following opportunely modified known chemical procedures and tested in luciferase and Escherichia coli β-galactosidase expressing CD4+, CXCR4+, CCR5+ TZM-bl cells. Results and Conclusion: a preliminary biological investigation on the synthesized small series of chloro-1,4-dimethyl-9H-carbazoles has been carried out. Among all tested compounds, a nitro-derivative (3b) showed the most interesting profile representing a suitable lead for the development of novel anti-HIV drugs.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Palella, F. J., Baker, R. K., Moorman, A. C., Chmiel, J. S., Wood, K. C., Brooks, J. T., & Holmberg, S. D. (2006) · JAIDS Journal of Acquired Immune Deficiency Syndromes · doi:10.1097/01.qai.0000233310.90484.16 · Cited by 1,350
The WHO public-health approach to antiretroviral treatment against HIV in resource-limited settings
Gilks, C. F., Crowley, S., Ekpini, R., Gove, S., Perriens, J., Souteyrand, Y., Sutherland, D., Vitoria, M., Guerma, T., & De Cock, K. (2006) · The Lancet · doi:10.1016/s0140-6736(06)69158-7 · Cited by 689
Recombination in viruses: Mechanisms, methods of study, and evolutionary consequences
Pérez-Losada, M., Arenas, M., Galán, J. C., Palero, F., & González-Candelas, F. (2015) · Infection, Genetics and Evolution · doi:10.1016/j.meegid.2014.12.022 · Cited by 450
Buonaguro, L., Tornesello, M. L., & Buonaguro, F. M. (2007) · Journal of Virology · doi:10.1128/jvi.00872-07 · Cited by 359
Small Molecule Inhibitors of CXCR4
Debnath, B., Xu, S., Grande, F., Garofalo, A., & Neamati, N. (2013) · Theranostics · doi:10.7150/thno.5376 · Cited by 273
Self-citationOwen, A., & Rannard, S. P. (2016) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2016.02.003 · Cited by 162
Sztuba-Solińska, J., Shenoy, S. R., Gareiss, P. C., Krumpe, L. R. H., Grice, S. F. J. L., O’Keefe, B. R., & Schneekloth, J. S. (2014) · Journal of the American Chemical Society · doi:10.1021/ja502754f · Cited by 144
Role of Marine Natural Products in the Genesis of Antiviral Agents
Gogineni, V., Schinazi, R. F., & Hamann, M. T. (2015) · Chemical Reviews · doi:10.1021/cr4006318 · Cited by 120
Parisi, O. I., Morelli, C., Puoci, F., et al. (2014) · Journal of Materials Chemistry B · doi:10.1039/c4tb00607k · Cited by 91
Gordts, S. C., Férir, G., D’huys, T., Petrova, M., Lebeer, S., Snoeck, R., Andreï, G., & Schols, D. (2015) · PLoS ONE · doi:10.1371/journal.pone.0131219 · Cited by 71
Self-citation
Cited by
Panzella, L., Moccia, F., Nasti, R., Marzorati, S., Verotta, L., & Napolitano, A. (2020) · Frontiers in Nutrition · doi:10.3389/fnut.2020.00060 · Cited by 448
Min, B. R., Solaiman, S., Waldrip, H. M., Parker, D., Todd, R. W., & Brauer, D. (2020) · Animal nutrition · doi:10.1016/j.aninu.2020.05.002 · Cited by 159
Perra, M., Lozano-Sánchez, J., Leyva-Jiménez, F.-J., Segura-Carretero, A., Pedraz, J. L., Bacchetta, G., Muntoni, A., De Gioannis, G., Manca, M. L., & Manconi, M. (2021) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2021.111959 · Cited by 53
Dietary total antioxidant capacity as a preventive factor against depression in climacteric women
Oliveira, N. G. D., Teixeira, I. T., Theodoro, H., & Branco, C. S. (2019) · Dementia & Neuropsychologia · doi:10.1590/1980-57642018dn13-030007 · Cited by 43
da Costa, E., Amaro, H. M., Melo, T., Guedes, A. C., & Domingues, M. R. (2020) · Journal of Applied Phycology · doi:10.1007/s10811-020-02173-6 · Cited by 41
Metadata
- Authors
- Saturnino, C., Grande, F., Aquaro, S., Caruso, A., Iacopetta, D., Bonomo, M., Longo, P., Schols, D., & Sinicropi, M.
- Venue
- Molecules
- Publisher
- MDPI AG
- Published
- 2018-01-30
- Volume
- 23
- Issue
- 2
- Pages
- 286
- ISSN
- 1420-3049 (ISSN-L)
- OpenAlex
- W2785546350
- Cited by
- 482
- References
- 26
- FWCI
- 80.75
- Type
- journal article
- Language
- en
- Open access
- gold
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Chloro-1,4-dimethyl-9H-carbazole Derivatives Displaying Anti-HIV Activity. https://app.cochat.ai/papers/10.3390/molecules23020286
- The paper
- Saturnino, C., Grande, F., Aquaro, S., Caruso, A., Iacopetta, D., Bonomo, M., Longo, P., Schols, D., & Sinicropi, M. (2018). Chloro-1,4-dimethyl-9H-carbazole Derivatives Displaying Anti-HIV Activity. Molecules. https://doi.org/10.3390/molecules23020286
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
