The DOI matches its Crossref record; 85 of the 85 references it cites were found in a registry or an index.
A Review of the Structure, Preparation, and Application of NLCs, PNPs, and PLNs
Open accessAbstract
Nanostructured lipid carriers (NLCs) are modified solid lipid nanoparticles (SLNs) that retain the characteristics of the SLN, improve drug stability and loading capacity, and prevent drug leakage. Polymer nanoparticles (PNPs) are an important component of drug delivery. These nanoparticles can effectively direct drug delivery to specific targets and improve drug stability and controlled drug release. Lipid–polymer nanoparticles (PLNs), a new type of carrier that combines liposomes and polymers, have been employed in recent years. These nanoparticles possess the complementary advantages of PNPs and liposomes. A PLN is composed of a core–shell structure; the polymer core provides a stable structure, and the phospholipid shell offers good biocompatibility. As such, the two components increase the drug encapsulation efficiency rate, facilitate surface modification, and prevent leakage of water-soluble drugs. Hence, we have reviewed the current state of development for the NLCs’, PNPs’, and PLNs’ structures, preparation, and applications over the past five years, to provide the basis for further study on a controlled release drug delivery system.
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Cites
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Lipid nanoparticles (SLN, NLC) in cosmetic and pharmaceutical dermal products
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Temporal targeting of tumour cells and neovasculature with a nanoscale delivery system
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Nonviral Gene Delivery: Principle, Limitations, and Recent Progress
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Lipid–polymer hybrid nanoparticles as a new generation therapeutic delivery platform: A review
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Nanostructured lipid carriers (NLC) in cosmetic dermal products☆
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Injectable matrices and scaffolds for drug delivery in tissue engineering
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Cited by
Lipid-Based Nanoparticles for Drug Delivery Systems
Samimi, S., Maghsoudnia, N., Eftekhari, R. B., & Dorkoosh, F. (2019) · Characterization and Biology of Nanomaterials for Drug Delivery · doi:10.1016/b978-0-12-814031-4.00003-9 · Cited by 266
Khan, S., Sharma, A., & Jain, V. (2023) · Advanced Pharmaceutical Bulletin · doi:10.34172/apb.2023.056 · Cited by 259
Metadata
- Authors
- Li, Q., Cai, T., Huang, Y., Xia, X., Cole, S., & Cai, Y.
- Venue
- Nanomaterials
- Publisher
- MDPI AG
- Published
- 2017-05-27
- Volume
- 7
- Issue
- 6
- Pages
- 122
- ISSN
- 2079-4991 (ISSN-L)
- OpenAlex
- W2620373091
- Cited by
- 282
- References
- 85
- FWCI
- 8.16
- Type
- journal article
- Language
- en
- Open access
- gold
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- Li, Q., Cai, T., Huang, Y., Xia, X., Cole, S., & Cai, Y. (2017). A Review of the Structure, Preparation, and Application of NLCs, PNPs, and PLNs. Nanomaterials. https://doi.org/10.3390/nano7060122
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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