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Cited by 316

The DOI matches its Crossref record; 189 of the 189 references it cites were found in a registry or an index.

Dietary Choline Intake: Current State of Knowledge Across the Life Cycle

Open access
Wiedeman, Alejandra, Barr, Susan, Green, Timothy, Xu, Zhaoming, Innis, Sheila, Kitts, David·2018·Nutrients

Abstract

Choline, an essential dietary nutrient for humans, is required for the synthesis of the neurotransmitter, acetylcholine, the methyl group donor, betaine, and phospholipids; and therefore, choline is involved in a broad range of critical physiological functions across all stages of the life cycle. The current dietary recommendations for choline have been established as Adequate Intakes (AIs) for total choline; however, dietary choline is present in multiple different forms that are both water-soluble (e.g., free choline, phosphocholine, and glycerophosphocholine) and lipid-soluble (e.g., phosphatidylcholine and sphingomyelin). Interestingly, the different dietary choline forms consumed during infancy differ from those in adulthood. This can be explained by the primary food source, where the majority of choline present in human milk is in the water-soluble form, versus lipid-soluble forms for foods consumed later on. This review summarizes the current knowledge on dietary recommendations and assessment methods, and dietary choline intake from food sources across the life cycle.

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Metadata

Authors
Wiedeman, A., Barr, S., Green, T., Xu, Z., Innis, S., & Kitts, D.
Venue
Nutrients
Publisher
MDPI AG
Published
2018-10-16
Volume
10
Issue
10
Pages
1513
ISSN
2072-6643 (ISSN-L)
OpenAlex
W2896011713
Cited by
316
References
189
FWCI
16.33
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: Dietary Choline Intake: Current State of Knowledge Across the Life Cycle. https://app.cochat.ai/papers/10.3390/nu10101513
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Wiedeman, A., Barr, S., Green, T., Xu, Z., Innis, S., & Kitts, D. (2018). Dietary Choline Intake: Current State of Knowledge Across the Life Cycle. Nutrients. https://doi.org/10.3390/nu10101513

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