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Cited by 33Birth, Development, and HealthDiabetes, Cardiovascular Risks, and LipoproteinsObesity, Physical Activity, Diet

Metabolic Syndrome and Its Associated Early-Life Factors among Chinese and Spanish Adolescents: A Pilot Study

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Wang, Jiao, Perona, Javier S., Schmidt-RioValle, Jacqueline, Chen, Yajun, Jing, Jin, González-Jiménez, Emilio·2019·Nutrients
DOI 10.3390/nu11071568PMC PMC6682950
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Abstract

Metabolic syndrome (MetS) is a growing problem worldwide in adolescents. This study compared two sample populations of young people in Spain and China, and analyzed the association of birth weight and breastfeeding duration with MetS. A cross-sectional study was conducted in adolescents (10–15 years old); 1150 Chinese and 976 Spanish adolescents. The variables analyzed were anthropometric characteristics, biochemical markers, and demographic characteristics using the same methodology and data collection protocol. Also, birth weight and breastfeeding were retrospectively analyzed during the first year of life. The results showed statistically significant differences between the two groups in reference to body mass index (BMI), blood pressure, triglyceride, glucose, and high-density lipoprotein cholesterol (HDL-C) levels. The MetS prevalence was higher in Spanish adolescents (2.5%) than in the Chinese group (0.5%). Breastfeeding duration was inversely associated with hypertriglyceridemia, low HDL-C, and MetS, whereas higher birth weight was associated with hyperglycemia, low HDL-C, hypertriglyceridemia, and abdominal obesity. Spanish adolescents showed more altered MetS components, and consequently, a higher MetS prevalence than the Chinese adolescents. This made them more vulnerable to cardiometabolic risk. Our results highlight the need for interventions designed by health professionals, which would encourage pregnant women to breastfeed their children.

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Authors
Wang, J., Perona, J. S., Schmidt-RioValle, J., Chen, Y., Jing, J., & González-Jiménez, E.
Affiliations
  • Sun Yat-sen University (CN)
  • Instituto de la Grasa (ES)
  • Departamento de Enfermería, CTS-436 Adscrito al Centro de Investigación Mente, Cerebro y Comportamiento (CIMCYC), University of Granada, Av/Ilustración 60, 18016 Granada, Spain
  • Department of Maternal and Child Health Care, School of Public Health, Sun Yat-Sen University, Guangzhou 510080, China
Corresponding author
Chen, Yajun
ORCID
Venue
Nutrients
Publisher
MDPI AG
Published
2019-07-11
Volume
11
Issue
7
Pages
1568
ISSN
2072-6643 (ISSN-L)
DOI
10.3390/nu11071568
PMC
PMC6682950
OpenAlex
W2958371547
Cited by
33
References
1
Citations by year
2026: 2 · 2025: 3 · 2024: 2 · 2023: 4 · 2022: 6 · 2021: 11 · 2020: 5
FWCI
5.72
Type
journal article
Language
en
Open access
Licence
Locations
  • Nutrients (publishedVersion, cc-by)
  • Europe PMC (PubMed Central) (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • Institutional Repository of the University of Granada (University of Granada) (submittedVersion, cc-by)
  • DIGITAL.CSIC (Spanish National Research Council (CSIC)) (submittedVersion, cc-by)
  • LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas) (submittedVersion, cc-by)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
Funders
  • National Natural Science Foundation of China (81673193)
  • Comisión Interministerial de Ciencia y Tecnología
Topics
  • Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Birth, Development, and Health
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Obesity, Physical Activity, Diet
Keywords
metabolic syndrome, adolescents, birth weight, breastfeeding duration, early life factors, hypertriglyceridemia, low HDL cholesterol, hyperglycemia, abdominal obesity, body mass index, blood pressure, cardiometabolic risk, cross-cultural comparison, Chinese adolescents, Spanish adolescents
MeSH terms
Adolescent, Birth Weight, Breast Feeding, Child, China, Female, Humans, Male, Pilot Projects, Spain, Metabolic Syndrome, White People, Asian People

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