Student or educator? Sign up with your school email and get 6 months of Pro free.
Cited by 16

The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.

Impact of Magnesium Supplementation in Muscle Damage of Professional Cyclists Competing in a Stage Race

Córdova, Alfredo, Mielgo-Ayuso, Juan, Roche, Enrique, Caballero-García, Alberto, Fernandez-Lázaro, Diego·2019·Nutrients

Abstract

Magnesium is a cofactor of different enzymatic reactions involved in anabolic and catabolic processes that affect muscular performance during exercise. In addition, it has been suggested that magnesium could participate in maintaining muscle integrity during demanding effort. The main purpose of this study was to analyze the effects of magnesium supplementation in preventing muscle damage in professional cyclists taking part in a 21-day cycling stage race. Eighteen male professional cyclists (n = 18) from two teams were recruited to participate in the research. They were divided into 2 groups: the control group (n = 9) and the magnesium-supplemented group (n = 9). The supplementation consisted of an intake of 400 mg/day of magnesium during the 3 weeks of competition. Blood samples were collected according to World Anti-Doping Agency rules at three specific moments during competition: immediately before the race; mid competition; and before the last stage. Levels of serum and erythrocyte magnesium, lactate dehydrogenase, creatinine kinase, aspartate transaminase, alanine transaminase, myoglobin, aldolase, total proteins, cortisol and creatinine were determined. Serum and erythrocyte magnesium levels decreased during the race. Circulating tissue markers increased at the end of the race in both groups. However, myoglobin increase was mitigated in the supplemented group compared with the controls. We conclude that magnesium supplementation seems to exert a protective effect on muscle damage.

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.3390/nu11081927

Cites

4 of 4 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Show all 4 references

Research works printed but not linked: 32

  1. Clarkson, 1995, Exercise and mineral status of athletes: Calcium, magnesium, phosphorus, and iron, Med. Sci. Sports Exerc., 27, 831, 10.1249/00005768-199506000-00007 · DOI
  2. Gimenez, 1990, Effect of swimming to exhaustion, at low temperatures, on serum Zn, Cu, Mg and Ca in rats, Physiol. Behav., 48, 595, 10.1016/0031-9384(90)90197-C · DOI
  3. Brilla, 1992, Effect of magnesium supplementation on strength training in humans, J. Am. Coll. Nutr., 11, 326, 10.1080/07315724.1992.10718233 · DOI · Paper page
  4. Shapiro, 1987, Changes in serum magnesium concentration after strenuous exercise, J. Am. Coll. Nutr., 6, 35, 10.1080/07315724.1987.10720163 · DOI
  5. Matias, 2015, Magnesium and phase angle: A prognostic tool for monitoring cellular integrity in judo athletes, Magnes. Res., 28, 92, 10.1684/mrh.2015.0389 · DOI
  6. Monteiro, 2016, Coordination between antioxidant defences might be partially modulated by magnesium status, Magnes. Res, 29, 161, 10.1684/mrh.2016.0414 · DOI
  7. Tang, 2016, Relationships between micronutrient losses in sweat and blood pressure among heat-exposed steelworkers, Ind. Health, 54, 215, 10.2486/indhealth.2014-0225 · DOI
  8. Bohl, 2002, Magnesium and Exercise, Crit. Rev. Food Sci. Nutr., 42, 533, 10.1080/20024091054247 · DOI
  9. Cordova, 1992, Changes on plasmatic and erythrocytic magnesium levels after high-intensity exercises in men, Physiol. Behav., 52, 819, 10.1016/0031-9384(92)90420-7 · DOI
  10. Nielsen, 2006, Update on the relationship between magnesium and exercise, Magnes. Res., 19, 180
  11. Alfredo, 2017, Effect of Magnesium Supplementation on Muscular Damage Markers in Basketball Players during a Full Season, J. Magnes. Res., 30, 61, 10.1684/mrh.2017.0424 · DOI
  12. Pojskic, 2018, Association Between Conditioning Capacities and Shooting Performance in Professional Basketball Players: An Analysis of Stationary and Dynamic Shooting Skills, J. Strength Cond. Res., 32, 1981, 10.1519/JSC.0000000000002100 · DOI
  13. 2015, Changes in Circulating Cytokines and Markers of Muscle Damage in Elite Cyclists during a Multi-stage Competition, Clin. Physiol. Funct. Imaging, 35, 351, 10.1111/cpf.12170 · DOI
  14. Schuchardt, 2017, Intestinal Absorption and Factors Influencing Bioavailability of Magnesium-An Update, Curr. Nutr. Food Sci., 13, 260, 10.2174/1573401313666170427162740 · DOI
  15. Black, 2012, Energy intakes of ultraendurance cyclists during competition, an observational study, Int. J. Sport Nutr. Exerc. Metab., 22, 19, 10.1123/ijsnem.22.1.19 · DOI · Paper page
  16. Foster, 1996, Athletic performance in relation to training load, Wis. Med J., 95, 370
  17. Córdova, A., Mielgo-Ayuso, J., Fernandez-Lazaro, C.I., Caballero-García, A., Roche, E., and Fernández-Lázaro, D. (2019). Effect of Iron Supplementation on the Modulation of Iron Metabolism, Muscle Damage Biomarkers and Cortisol in Professional Cyclists. Nutrients, 11. · DOI
  18. Czaja, 2011, Evaluation for magnesium and vitamin B6 supplementation among Polish elite athletes, Roczniki Państwowego Zakładu Higieny, 62, 413
  19. Muros, 2019, Nutritional Intake and Body Composition Changes in a UCI World Tour Cycling Team during the Tour of Spain, Eur. J. Sport Sci., 19, 86, 10.1080/17461391.2018.1497088 · DOI
  20. Navas, 1997, Compartmental shifts of calcium and magnesium as a result of swimming and swimming training in rats, Med. Sci. Sports Exerc., 29, 882, 10.1097/00005768-199707000-00007 · DOI
  21. Shapira, 1989, Delayed metabolic changes after strenuous exertion in trained young men, Magnes. Res., 2, 211
  22. Shapiro, 1999, Not Only Strenuous but also Sustained Moderate Physical Effort Causes Magnesium, Trace Elem. Electrolytes, 16, 156
  23. Gueux, 2002, Increased phagocytosis and production of reactive oxygen species by neutrophils during magnesium deficiency in rats and inhibition by high magnesium concentration, Br. J. Nutr., 87, 107, 10.1079/BJN2001498 · DOI
  24. Okazaki, 2013, Significant positive relationship between serum magnesium and muscle quality in maintenance hemodialysis patients, Magnes Res, 26, 182, 10.1684/mrh.2014.0352 · DOI
  25. Rock, 1995, Dietary magnesium deficiency in rats enhances free radical production in skeletal muscle, J. Nutr., 125, 1205
  26. 2002, Relationship between serum magnesium levels and C-reactive protein concentration, in non-diabetic, non-hypertensive obese subjects, Int. J. Obes., 26, 469, 10.1038/sj.ijo.0801954 · DOI
  27. Colombini, 2012, Serum Creatine Kinase Activity and its Relationship with Renal Function Indices in Professional Cyclists during the Giro D’Italia 3-Week Stage Race, Clin. J. Sport Med., 22, 408, 10.1097/JSM.0b013e31825e66cc · DOI
  28. Cordova, 2014, Oxidative Stress Markers After a Race in Professional Cyclists, Int. J. Sport Nutr. Exerc. Metab., 25, 171, 10.1123/ijsnem.2014-0090 · DOI
  29. Mena, 1996, Changes in plasma enzyme activities in professional racing cyclists, Br. J. Sports Med., 30, 122, 10.1136/bjsm.30.2.122 · DOI
  30. Shing, 2016, Acute Protease Supplementation Effects on Muscle Damage and Recovery across Consecutive Days of Cycle Racing, Eur. J. Sport Sci., 16, 206, 10.1080/17461391.2014.1001878 · DOI
  31. Dajak, 2016, ACTH, Cortisol and IL-6 Levels in Athletes following Magnesium Supplementation, J. Med. Biochem., 35, 375, 10.1515/jomb-2016-0021 · DOI · Paper page
  32. Nowacki, 2000, Inflammatory response following acute magnesium deficiency in the rat, Biochim. Biophys. Acta, 1501, 91, 10.1016/S0925-4439(00)00018-1 · DOI · Paper page

Cited by

Metadata

Authors
Córdova, A., Mielgo-Ayuso, J., Roche, E., Caballero-García, A., & Fernandez-Lázaro, D.
Affiliations
  • Department of Biochemistry and Physiology, Faculty of Health of Sciences, University of Valladolid Campus de Soria, 42003 Soria, Spain
  • Department of Applied Biology-Nutrition and Institute of Bioengineering, Alicante Institute for Health and Biomedical Research (ISABIAL Foundation), 03550 Alicante, Spain
  • Department of Anatomy and Radiology, Faculty of Health of Sciences, University of Valladolid, 42004 Soria, Spain
  • Department of Cell Biology, Histology and Pharmacology, Faculty of Health of Sciences, University of Valladolid, 42004 Soria, Spain
Venue
Nutrients
Publisher
MDPI AG
Published
2019-08-16
Volume
11
Issue
8
Pages
1927
ISSN
2072-6643
Cited by
16
References
4
Language
en

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.