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Cited by 784

The DOI matches its Crossref record; 102 of the 102 references it cites were found in a registry or an index.

Postbiotics—A Step Beyond Pre- and Probiotics

Open access
Żółkiewicz, Jakub, Marzec, Aleksandra, Ruszczyński, Marek, Feleszko, Wojciech·2020·Nutrients

Abstract

As an imbalance in the intestinal microbiota can lead to the development of several diseases (e.g., type 1 diabetes, cancer, among others), the use of prebiotics, probiotics, and postbiotics to alter the gut microbiome has attracted recent interest. Postbiotics include any substance released by or produced through the metabolic activity of the microorganism, which exerts a beneficial effect on the host, directly or indirectly. As postbiotics do not contain live microorganisms, the risks associated with their intake are minimized. Here, we provided a critical review of postbiotics described in the literature, including their mechanisms of action, clinical characteristics, and potential therapeutic applications. We detailed the pleiotropic effects of postbiotics, including their immunomodulatory, anti-inflammatory, antioxidant, and anti-cancer properties. Although the use of postbiotics is an attractive strategy for altering the microbiome, further study into its efficacy and safety is warranted.

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Crossref · 10.3390/nu12082189

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Metadata

Authors
Żółkiewicz, J., Marzec, A., Ruszczyński, M., & Feleszko, W.
Venue
Nutrients
Publisher
MDPI AG
Published
2020-07-23
Volume
12
Issue
8
Pages
2189
ISSN
2072-6643 (ISSN-L)
OpenAlex
W3045231380
Cited by
784
References
102
FWCI
49.57
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: Postbiotics—A Step Beyond Pre- and Probiotics. https://app.cochat.ai/papers/10.3390/nu12082189
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Żółkiewicz, J., Marzec, A., Ruszczyński, M., & Feleszko, W. (2020). Postbiotics—A Step Beyond Pre- and Probiotics. Nutrients. https://doi.org/10.3390/nu12082189

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.