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Cited by 280

The DOI matches its Crossref record; 143 of the 143 references it cites were found in a registry or an index.

Nutrition and Frailty: Opportunities for Prevention and Treatment

Open access
Ni Lochlainn, Mary, Cox, Natalie J., Wilson, Thomas, Hayhoe, Richard P. G., Ramsay, Sheena E., Granic, Antoneta, Isanejad, Masoud, Roberts, Helen C., Wilson, Daisy, Welch, Carly, Hurst, Christopher, Atkins, Janice L., Mendonça, Nuno, Horner, Katy, Tuttiett, Esme R., Morgan, Yvie, Heslop, Phil, Williams, Elizabeth A., Steves, Claire J., Greig, Carolyn, Draper, John, Corish, Clare A., Welch, Ailsa, Witham, Miles D., Sayer, Avan A., Robinson, Sian·2021·Nutrients
DOI 10.3390/nu13072349
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Abstract

Frailty is a syndrome of growing importance given the global ageing population. While frailty is a multifactorial process, poor nutritional status is considered a key contributor to its pathophysiology. As nutrition is a modifiable risk factor for frailty, strategies to prevent and treat frailty should consider dietary change. Observational evidence linking nutrition with frailty appears most robust for dietary quality: for example, dietary patterns such as the Mediterranean diet appear to be protective. In addition, research on specific foods, such as a higher consumption of fruit and vegetables and lower consumption of ultra-processed foods are consistent, with healthier profiles linked to lower frailty risk. Few dietary intervention studies have been conducted to date, although a growing number of trials that combine supplementation with exercise training suggest a multi-domain approach may be more effective. This review is based on an interdisciplinary workshop, held in November 2020, and synthesises current understanding of dietary influences on frailty, focusing on opportunities for prevention and treatment. Longer term prospective studies and well-designed trials are needed to determine the causal effects of nutrition on frailty risk and progression and how dietary change can be used to prevent and/or treat frailty in the future.

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Metadata

Authors
Ni Lochlainn, M., Cox, N. J., Wilson, T., Hayhoe, R. P. G., Ramsay, S. E., Granic, A., Isanejad, M., Roberts, H. C., Wilson, D., Welch, C., Hurst, C., Atkins, J. L., Mendonça, N., Horner, K., Tuttiett, E. R., Morgan, Y., Heslop, P., Williams, E. A., Steves, C. J., Greig, C., Draper, J., Corish, C. A., Welch, A., Witham, M. D., Sayer, A. A., & Robinson, S.
Venue
Nutrients
Publisher
MDPI AG
Published
2021-07-09
Volume
13
Issue
7
Pages
2349
ISSN
2072-6643 (ISSN-L)
DOI
10.3390/nu13072349
OpenAlex
W3182756837
Cited by
280
References
143
FWCI
16.82
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: Nutrition and Frailty: Opportunities for Prevention and Treatment. https://app.cochat.ai/papers/10.3390/nu13072349
The paper
Ni Lochlainn, M., Cox, N. J., Wilson, T., Hayhoe, R. P. G., Ramsay, S. E., Granic, A., Isanejad, M., Roberts, H. C., Wilson, D., Welch, C., Hurst, C., Atkins, J. L., Mendonça, N., Horner, K., Tuttiett, E. R., Morgan, Y., Heslop, P., Williams, E. A., Steves, C. J., . . . Robinson, S. (2021). Nutrition and Frailty: Opportunities for Prevention and Treatment. Nutrients. https://doi.org/10.3390/nu13072349

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.