The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.
Nanomaterials Designed for Antiviral Drug Delivery Transport across Biological Barriers
Open accessAbstract
Viral infections are a major global health problem, representing a significant cause of mortality with an unfavorable continuously amplified socio-economic impact. The increased drug resistance and constant viral replication have been the trigger for important studies regarding the use of nanotechnology in antiviral therapies. Nanomaterials offer unique physico-chemical properties that have linked benefits for drug delivery as ideal tools for viral treatment. Currently, different types of nanomaterials namely nanoparticles, liposomes, nanospheres, nanogels, nanosuspensions and nanoemulsions were studied either in vitro or in vivo for drug delivery of antiviral agents with prospects to be translated in clinical practice. This review highlights the drug delivery nanosystems incorporating the major antiviral classes and their transport across specific barriers at cellular and intracellular level. Important reflections on nanomedicines currently approved or undergoing investigations for the treatment of viral infections are also discussed. Finally, the authors present an overview on the requirements for the design of antiviral nanotherapeutics.
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Cites
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Cited by
Toward Nanotechnology-Enabled Approaches against the COVID-19 Pandemic
Weiss, C., Carriere, M., Fusco, L., Capua, I., Regla-Nava, J. A., Pasquali, M., Scott, J. A., Vitale, F., Unal, M. A., Mattevi, C., et al. (2020) · ACS Nano · doi:10.1021/acsnano.0c03697 · Cited by 601
Surface Design for Antibacterial Materials: From Fundamentals to Advanced Strategies
Li, W., Thian, E. S., Wang, M., Wang, Z., & Ren, L. (2021) · Advanced Science · doi:10.1002/advs.202100368 · Cited by 429
Nanotechnology-based antiviral therapeutics
Chakravarty, M., & Vora, A. (2021) · Drug Delivery and Translational Research · doi:10.1007/s13346-020-00818-0 · Cited by 334
Metadata
- Authors
- Cojocaru, F.-D., Botezat, D., Gardikiotis, I., Uritu, C.-M., Dodi, G., Trandafir, L., Rezus, C., Rezus, E., Tamba, B.-I., & Mihai, C.-T.
- Venue
- Pharmaceutics
- Publisher
- MDPI AG
- Published
- 2020-02-18
- Volume
- 12
- Issue
- 2
- Pages
- 171
- ISSN
- 1999-4923 (ISSN-L)
- OpenAlex
- W3008589136
- Cited by
- 206
- References
- 8
- FWCI
- 8.84
- Type
- journal article
- Language
- en
- Open access
- gold
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- Cojocaru, F.-D., Botezat, D., Gardikiotis, I., Uritu, C.-M., Dodi, G., Trandafir, L., Rezus, C., Rezus, E., Tamba, B.-I., & Mihai, C.-T. (2020). Nanomaterials Designed for Antiviral Drug Delivery Transport across Biological Barriers. Pharmaceutics. https://doi.org/10.3390/pharmaceutics12020171
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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