Cited by 41Essential Oils and Antimicrobial ActivityWound Healing and TreatmentsPhytochemistry and biological activity of medicinal plants

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The Antibacterial and Wound Healing Properties of Natural Products: A Review on Plant Species with Therapeutic Potential against Staphylococcus aureus Wound Infections

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Morguette, Ana Elisa Belotto, Bartolomeu-Gonçalves, Guilherme, Andriani, Gabriella Maria, Bertoncini, Giovana Elika Silveira, de Castro, Isabela Madeira, de Almeida Spoladori, Laís Fernanda, Bertão, Ariane Mayumi Saito, Tavares, Eliandro Reis, Yamauchi, Lucy Megumi, Yamada-Ogatta, Sueli Fumie·2023·Plants

DOI 10.3390/plants12112147PMC PMC10255540

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Abstract

Wounds of an acute or chronic etiology affect millions of people worldwide, with increasing prevalence every year. Microbial infections are one of the main causes that impair the wound healing process, and Staphylococcus aureus, a commensal member of the skin microbiota, is one of the main causative agents of wound infections. Crucially, a high proportion of these infections are caused by methicillin-resistant Staphylococcus aureus, which, in addition to β-lactams, has acquired resistance to almost all the antibacterial agents used to treat it, limiting therapeutic options. Studies on the antimicrobial and healing activities of extracts, essential oils, or metabolites obtained from native plants have been reported in many countries that have a diverse flora and traditions with the use of medicinal plants for the treatment of wound infections. Due to their great chemical diversity, plants have proven to be promising sources of bioactive molecules for the discovery and development of new drugs or strategies for the treatment of wounds. This review highlights the main herbal preparations that have antimicrobial and healing activities with potential for the treatment of wound infections caused by Staphylococcus aureus.

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Authors: Morguette, A. E. B., Bartolomeu-Gonçalves, G., Andriani, G. M., Bertoncini, G. E. S., de Castro, I. M., de Almeida Spoladori, L. F., Bertão, A. M. S., Tavares, E. R., Yamauchi, L. M., & Yamada-Ogatta, S. F.
Affiliations: Universidade Estadual de Londrina (BR)
Programa de Pós-Graduação em Microbiologia, Departamento de Microbiologia, Centro de Ciências Biológicas, Universidade Estadual de Londrina, Londrina 86057-970, PR, Brazil
Centro Universitário Filadélfia (BR)
ORCID: Bartolomeu-Gonçalves, Guilherme
Andriani, Gabriella Maria
de Castro, Isabela Madeira
Tavares, Eliandro Reis
Yamauchi, Lucy Megumi
Yamada-Ogatta, Sueli Fumie
Venue: Plants
Publisher: MDPI AG
Published: 2023-05-29
Volume: 12
Issue: 11
Pages: 2147
ISSN: 2223-7747 (ISSN-L)
DOI: 10.3390/plants12112147
PMC: PMC10255540
OpenAlex: W4380225223
Cited by: 31
References: 103
Citations by year: 2026: 8 · 2025: 16 · 2024: 6 · 2023: 1
FWCI: 0.72
Type: journal article
Language: en
Open access: gold
doi.org
Licence: cc-by
creativecommons.org/licenses/by/4.0/ (vor)
Locations: Plants (publishedVersion, cc-by)
PubMed Central (publishedVersion, cc-by)
PubMed (publishedVersion)
DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Funders: Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
Conselho Nacional de Desenvolvimento Científico e Tecnológico (309260/2022-1)
Topics: Life Sciences › Agricultural and Biological Sciences › Food Science › Essential Oils and Antimicrobial Activity
Health Sciences › Medicine › Surgery › Wound Healing and Treatments
Life Sciences › Agricultural and Biological Sciences › Plant Science › Phytochemistry and biological activity of medicinal plants
Keywords: Staphylococcus aureus, methicillin-resistant Staphylococcus aureus, wound infection, wound healing, antibacterial activity, medicinal plants, plant extracts, essential oils, antimicrobial resistance, herbal products

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The Antibacterial and Wound Healing Properties of Natural Products: A Review on Plant Species with Therapeutic Potential against Staphylococcus aureus Wound Infections

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