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Cited by 578

The DOI matches its Crossref record; 128 of the 128 references it cites were found in a registry or an index.

The Use of Natural Polymers in Tissue Engineering: A Focus on Electrospun Extracellular Matrix Analogues

Open access
Sell, Scott A., Wolfe, Patricia S., Garg, Koyal, McCool, Jennifer M., Rodriguez, Isaac A., Bowlin, Gary L.·2010·Polymers

Abstract

Natural polymers such as collagens, elastin, and fibrinogen make up much of the body’s native extracellular matrix (ECM). This ECM provides structure and mechanical integrity to tissues, as well as communicating with the cellular components it supports to help facilitate and regulate daily cellular processes and wound healing. An ideal tissue engineering scaffold would not only replicate the structure of this ECM, but would also replicate the many functions that the ECM performs. In the past decade, the process of electrospinning has proven effective in creating non-woven ECM analogue scaffolds of micro to nanoscale diameter fibers from an array of synthetic and natural polymers. The ability of this fabrication technique to utilize the aforementioned natural polymers to create tissue engineering scaffolds has yielded promising results, both in vitro and in vivo, due in part to the enhanced bioactivity afforded by materials normally found within the human body. This review will present the process of electrospinning and describe the use of natural polymers in the creation of bioactive ECM analogues in tissue engineering.

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Crossref · 10.3390/polym2040522

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Metadata

Authors
Sell, S. A., Wolfe, P. S., Garg, K., McCool, J. M., Rodriguez, I. A., & Bowlin, G. L.
Venue
Polymers
Publisher
MDPI AG
Published
2010-11-09
Volume
2
Issue
4
Pages
522-553
ISSN
2073-4360 (ISSN-L)
OpenAlex
W2046164358
Cited by
578
References
128
FWCI
6.35
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: The Use of Natural Polymers in Tissue Engineering: A Focus on Electrospun Extracellular Matrix Analogues. https://app.cochat.ai/papers/10.3390/polym2040522
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Sell, S. A., Wolfe, P. S., Garg, K., McCool, J. M., Rodriguez, I. A., & Bowlin, G. L. (2010). The Use of Natural Polymers in Tissue Engineering: A Focus on Electrospun Extracellular Matrix Analogues. Polymers. https://doi.org/10.3390/polym2040522

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Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.