The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
Toxicity of Glutathione-Binding Metals: A Review of Targets and Mechanisms
Open accessAbstract
Mercury, cadmium, arsenic and lead are among priority metals for toxicological studies due to the frequent human exposure and to the significant burden of disease following acute and chronic intoxication. Among their common characteristics is chemical affinity to proteins and non-protein thiols and their ability to generate cellular oxidative stress by the best-known Fenton mechanism. Their health effects are however diverse: kidney and liver damage, cancer at specific sites, irreversible neurological damages with metal-specific features. Mechanisms for the induction of oxidative stress by interaction with the cell thiolome will be presented, based on literature evidence and of experimental findings.
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Cites
Metals, Toxicity and Oxidative Stress
Valko, M., Morris, H., & Cronin, M. (2005) · Current Medicinal Chemistry · doi:10.2174/0929867053764635 · Cited by 5,018
Oxidative mechanisms in the toxicity of metal ions
Stohs, S. J., & Bagchi, D. (1995) · Free Radical Biology and Medicine · doi:10.1016/0891-5849(94)00159-h · Cited by 4,219
Global analysis of protein expression in yeast
Ghaemmaghami, S., Huh, W.-K., Bower, K., Howson, R. W., Belle, A., Dephoure, N., O'Shea, E. K., & Weissman, J. S. (2003) · Nature · doi:10.1038/nature02046 · Cited by 3,750
Kell, D. B. (2010) · Archives of Toxicology · doi:10.1007/s00204-010-0577-x · Cited by 361
Hartwig, A. (2001) · Antioxidants & Redox Signaling · doi:10.1089/15230860152542970 · Cited by 269
Wang, S. K., Weaver, J. D., Zhang, S., & Lei, X. G. (2011) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2011.03.018 · Cited by 28
Cited by
Role of Glutathione in Cancer: From Mechanisms to Therapies
Kennedy, L., Sandhu, J. K., Harper, M.-E., & Cuperlovic-Culf, M. (2020) · Biomolecules · doi:10.3390/biom10101429 · Cited by 880
Metal–Organic Frameworks for Cell and Virus Biology: A Perspective
Riccò, R., Liang, W., Li, S., Gassensmith, J. J., Caruso, F., Doonan, C., & Falcaro, P. (2018) · ACS Nano · doi:10.1021/acsnano.7b08056 · Cited by 293
Metadata
- Authors
- Rubino, F.
- Venue
- Toxics
- Publisher
- MDPI AG
- Published
- 2015-01-26
- Volume
- 3
- Issue
- 1
- Pages
- 20-62
- ISSN
- 2305-6304 (ISSN-L)
- OpenAlex
- W2072613715
- Cited by
- 173
- References
- 6
- FWCI
- 4.22
- Type
- journal article
- Language
- en
- Open access
- gold
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
