A review of osteoarthritis and obesity: current understanding of the relationship and benefit of obesity treatment and prevention in the dog
Open accessAbstract
Summary: Obesity is an increasingly important health problem for both man and dog. Osteoarthritis (OA) is a significant cause of pain and disability in both species. A link between obesity and OA has been established in man, though the exact mechanism of the relationship remains to be fully elucidated – current research supports both biomechanical and biochemical theories. There is good evidence (class I*) to support weight loss as an effective treatment for human knee OA. In the dog, the relationship is just beginning to be investigated. The results of one study in dogs (class IV evidence*) suggest that preventing the development of overweightness and obesity reduces the prevalence of hip dysplasia and OA of the hip and other joints. Three other studies (class III and IV evidence*) support weight loss as an effective treatment for OA in affected over-weight and obese dogs. Further research could yield greater understanding of the pathophysiology of this relationship, perhaps identifying novel therapeutic targets. Confirmation and better understanding of the positive effect of treating and preventing obesity on symptoms and prevalence of OA is likely to be valuable in the campaign against canine obesity.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Overweight dogs are more likely to be diagnosed with urinary tract diseases; obese and overweight dogs are at risk developing orthopedic disorders and hypothyroidism.
“Overweight dogs are more likely to be diagnosed with, e.g., urinary tract diseases. Obese and overweight dogs are at risk developing orthopedic disorders and hypothyroidism [52,53].”
From A One Health Perspective on the Human-Companion Animal Relationship with Emphasis on Zoonotic Aspects. (2020) · cites this paper as [53]
Cites
Ogden, C. L., Yanovski, S. Z., Carroll, M. D., & Flegal, K. M. (2007) · Gastroenterology · doi:10.1053/j.gastro.2007.03.052 · Cited by 1,561 · see citing works
A Framework for the in Vivo Pathomechanics of Osteoarthritis at the Knee
Andriacchi, T. P., Mündermann, A., Smith, R. L., Alexander, E. J., Dyrby, C. O., & Koo, S. (2004) · Annals of Biomedical Engineering · doi:10.1023/b:abme.0000017541.82498.37 · Cited by 1,068 · see citing works
The Growing Problem of Obesity in Dogs and Cats
German, A. J. (2006) · Journal of Nutrition · doi:10.1093/jn/136.7.1940s · Cited by 860 · see citing works
Christensen, R., Bartels, E. M., Astrup, A. V., & Bliddal, H. (2007) · Annals of the Rheumatic Diseases · doi:10.1136/ard.2006.065904 · Cited by 632 · see citing works
The role of ambulatory mechanics in the initiation and progression of knee osteoarthritis
Andriacchi, T. P., & Mündermann, A. (2006) · Current Opinion in Rheumatology · doi:10.1097/01.bor.0000240365.16842.4e · Cited by 629 · see citing works
Effects of diet restriction on life span and age-related changes in dogs
Kealy, R. D., Lawler, D. F., Ballam, J. M., Mantz, S. L., Biery, D. N., Greeley, E. H., Lust, G., Segre, M., Smith, G. K., & Stowe, H. D. (2002) · Journal of the American Veterinary Medical Association · doi:10.2460/javma.2002.220.1315 · Cited by 617 · see citing works
Grotle, M., Hagen, K. B., Natvig, B., Dahl, F. A., & Kvien, T. K. (2008) · BMC Musculoskeletal Disorders · doi:10.1186/1471-2474-9-132 · Cited by 613 · see citing works
Reijman, M., Pols, H. A. P., Bergink, A. P., Hazes, J. M. W., Belo, J. N., Lievense, A. M., & Bierma‐Zeinstra, S. (2006) · Annals of the Rheumatic Diseases · doi:10.1136/ard.2006.053538 · Cited by 471 · see citing works
McGreevy, P. D., Thomson, P. C., Pride, C., Fawcett, A., Grassi, T., & Jones, B. (2005) · Veterinary Record · doi:10.1136/vr.156.22.695 · Cited by 377 · see citing works
Johnston, S. A. (1997) · Veterinary Clinics of North America Small Animal Practice · doi:10.1016/s0195-5616(97)50076-3 · Cited by 362 · see citing works
The effect of body weight on progression of knee osteoarthritis is dependent on alignment
Felson, D. T., Goggins, J., Niu, J., Zhang, Y., & Hunter, D. J. (2004) · Arthritis & Rheumatism · doi:10.1002/art.20726 · Cited by 331 · see citing works
Study of obesity in dogs visiting veterinary practices in the United Kingdom
Edney, A. T. B., & Smith, P. (1986) · Veterinary Record · doi:10.1136/vr.118.14.391 · Cited by 313 · see citing works
Influence of obesity on the development of osteoarthritis of the hip: a systematic review
Lievense, A. M. (2002) · British journal of rheumatology · doi:10.1093/rheumatology/41.10.1155 · Cited by 307 · see citing works
The Potential of Adiponectin in Driving Arthritis
Ehling, A., Schäffler, A., Herfarth, H. H., Tarner, I. H., Anders, S., Distler, O., Paul, G., Distler, J. H. W., Gay, S., Schölmerich, J., et al. (2006) · The Journal of Immunology · doi:10.4049/jimmunol.176.7.4468 · Cited by 279 · see citing works
Obesity: The Integrated Roles of Environment and Genetics
Speakman, J. R. (2004) · Journal of Nutrition · doi:10.1093/jn/134.8.2090s · Cited by 275 · see citing works
Simopoulou, T., Malizos, Κ. Ν., Iliopoulos, D., Stefanou, N., Papatheodorou, L. K., Ιωάννου, Μ., & Tsezou, A. (2007) · Osteoarthritis and Cartilage · doi:10.1016/j.joca.2007.01.018 · Cited by 275 · see citing works
Lago, R., Gómez, R., Otero, M., Lago, F., Gallego, R., Diéguez, C., Gómez-Reino, J. J., & Gualillo, O. (2008) · Osteoarthritis and Cartilage · doi:10.1016/j.joca.2007.12.008 · Cited by 273 · see citing works
Small animal clinical nutrition
Hand, M. S., Morris, M. L., & Novotny, B. J. (2000) · Medical Entomology and Zoology · Cited by 266 · see citing works
Effect of weight reduction on clinical signs of lameness in dogs with hip osteoarthritis
Impellizeri, J. A., Tetrick, M. A., & Muir, P. (2000) · Journal of the American Veterinary Medical Association · doi:10.2460/javma.2000.216.1089 · Cited by 251 · see citing works
Loeser, R. F., Yammani, R. R., Carlson, C. S., Chen, H., Cole, A. A., Im, H., Bursch, L. S., & Yan, S. D. (2005) · Arthritis & Rheumatism · doi:10.1002/art.21199 · Cited by 244 · see citing works
Osteoarthritis: rational approach to treating the individual
Jüni, P., Reichenbach, S., & Dieppe, P. A. (2006) · Best Practice & Research Clinical Rheumatology · doi:10.1016/j.berh.2006.05.002 · Cited by 237 · see citing works
Is progressive osteoarthritis an atheromatous vascular disease?
Conaghan, P. G., Vanharanta, H., & Dieppe, P. A. (2005) · Annals of the Rheumatic Diseases · doi:10.1136/ard.2005.039263 · Cited by 207 · see citing works
Do metabolic factors add to the effect of overweight on hand osteoarthritis? The Rotterdam Study
Dahaghin, S., Bierma‐Zeinstra, S., Koes, B. W., Hazes, J. M. W., & Pols, H. A. P. (2007) · Annals of the Rheumatic Diseases · doi:10.1136/ard.2005.045724 · Cited by 205 · see citing works
Lago, R., Gómez, R., Lago, F., Gómez-Reino, J. J., & Gualillo, O. (2008) · Cellular Immunology · doi:10.1016/j.cellimm.2007.09.004 · Cited by 185 · see citing works
Kealy, R. D., Lawler, D. F., Ballam, J. M., Lust, G., Biery, D. N., Smith, G. K., & Mantz, S. L. (2000) · Journal of the American Veterinary Medical Association · doi:10.2460/javma.2000.217.1678 · Cited by 185 · see citing works
Lifelong diet restriction and radiographic evidence of osteoarthritis of the hip joint in dogs
Smith, G. K., Paster, E. R., Powers, M. Y., Lawler, D. F., Biery, D. N., Shofer, F. S., McKelvie, P. J., & Kealy, R. D. (2006) · Journal of the American Veterinary Medical Association · doi:10.2460/javma.229.5.690 · Cited by 175 · see citing works
The AGE of the matrix: chemistry, consequence and cure
DeGroot, J. (2004) · Current Opinion in Pharmacology · doi:10.1016/j.coph.2004.01.007 · Cited by 165 · see citing works
Effects of limited food consumption on the incidence of hip dysplasia in growing dogs
Kealy, R. D., Olsson, S. E., Monti, K. L., Lawler, D. F., Biery, D. N., Helms, R. W., Lust, G., & Smith, G. K. (1992) · Journal of the American Veterinary Medical Association · doi:10.2460/javma.1992.201.06.857 · Cited by 152 · see citing works
Steenvoorden, M. M. C., Huizinga, T. W. J., Verzijl, N., Bank, R. A., Ronday, H. K., Luning, H. A. F., Lafeber, F. P. J. G., Toes, R. E. M., & DeGroot, J. (2005) · Arthritis & Rheumatism · doi:10.1002/art.21523 · Cited by 149 · see citing works
Kealy, R. D., Lawler, D. F., Ballam, J. M., Lust, G., Smith, G. K., Biery, D. N., & Olsson, S. (1997) · Journal of the American Veterinary Medical Association · doi:10.2460/javma.1997.210.02.222 · Cited by 149 · see citing works
Applications of Evidence‐Based Medicine: Cranial Cruciate Ligament Injury Repair in the Dog
Aragon, C. L., & Budsberg, S. C. (2005) · Veterinary Surgery · doi:10.1111/j.1532-950x.2005.00016.x · Cited by 147 · see citing works
Mlacnik, E., Bockstahler, B. A., Müller, M., Tetrick, M. A., Nap, R. C., & Zentek, J. (2006) · Journal of the American Veterinary Medical Association · doi:10.2460/javma.229.11.1756 · Cited by 119 · see citing works
Self-citationHenderson, C. J., SPECKER, B. L., Sierra, R. I., Campaigne, B. N., & Lovell, D. J. (2000) · Arthritis & Rheumatism · doi:10.1002/1529-0131(200003)43:3 · Cited by 103 · see citing works
Influence of lifetime food restriction on causes, time, and predictors of death in dogs
Lawler, D. F., Evans, R. H., Larson, B. T., Spitznagel, E. L., Ellersieck, M. R., & Kealy, R. D. (2005) · Journal of the American Veterinary Medical Association · doi:10.2460/javma.2005.226.225 · Cited by 100 · see citing works
Correlation between plasma leptin concentration and body fat content in dogs
Sagawa, M., Nakadomo, F., Honjoh, T., Ishioka, K., & Saito, M. (2002) · American Journal of Veterinary Research · doi:10.2460/ajvr.2002.63.7 · Cited by 82 · see citing works
Influence of borderline hip dysplasia on joint kinematics of clinically sound Belgian Shepherd dogs
Bockstahler, B. A., Henninger, W., Müller, M., Mayrhofer, E., Peham, C., & Podbregar, I. (2007) · American Journal of Veterinary Research · doi:10.2460/ajvr.68.3.271 · Cited by 72 · see citing works
Self-citationFurther evidence for leptin involvement in cartilage homeostases
Gualillo, O. (2007) · Osteoarthritis and Cartilage · doi:10.1016/j.joca.2007.04.015 · Cited by 41 · see citing works
Controlling the obesity epidemic is important for maintaining musculoskeletal health
Woolf, A. D., Breedveld, F. C., & Kvien, T. K. (2006) · Annals of the Rheumatic Diseases · doi:10.1136/ard.2006.058172 · Cited by 37 · see citing works
The Effects of Lifetime Food Restriction on the Development of Osteoarthritis in the Canine Shoulder
Runge, J. J., Biery, D. N., Lawler, D. F., Gregor, T. P., Evans, R. H., Kealy, R. D., Szabo, S. D., & Smith, G. K. (2008) · Veterinary Surgery · doi:10.1111/j.1532-950x.2007.00354.x · Cited by 36 · see citing works
Outcomes‐Based Medicine in Veterinary Surgery: Levels of Evidence
Innes, J. (2007) · Veterinary Surgery · doi:10.1111/j.1532-950x.2007.00329.x · Cited by 27 · see citing works
Associations Between Canine Juvenile Weight Gain and Coxofemoral Joint Laxity at 16 Weeks of Age
Lopez, M. J., QUINN, M. M., & Markel, M. D. (2006) · Veterinary Surgery · doi:10.1111/j.1532-950x.2006.00139.x · Cited by 7 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Overgaauw, P. A. M., Vinke, C. M., van Hagen, M. A. E., & Lipman, L. J. A. (2020) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph17113789 · Cited by 301 · see citing works
“Obese and overweight dogs are at risk developing orthopedic disorders and hypothyroidism [52,53].”
BackgroundObesity and Associated Comorbidities in People and Companion Animals: A One Health Perspective
Chandler, M. L., Cunningham, S. A., Lund, E., Khanna, C., Naramore, R., Patel, A. V., & Day, M. J. (2017) · Journal of Comparative Pathology · doi:10.1016/j.jcpa.2017.03.006 · Cited by 221 · see citing works
On the predictive utility of animal models of osteoarthritis
Malfait, A., & Little, C. B. (2015) · Arthritis Research & Therapy · doi:10.1186/s13075-015-0747-6 · Cited by 168 · see citing works
2014 AAHA Weight Management Guidelines for Dogs and Cats*†
Brooks, D., Churchill, J. A., Fein, K., Linder, D. E., Michel, K. E., Tudor, K., Ward, E., & Witzel, A. L. (2013) · Journal of the American Animal Hospital Association · doi:10.5326/jaaha-ms-6331 · Cited by 150 · see citing works
The effect of weight loss on lameness in obese dogs with osteoarthritis
Marshall, W. G., Hazewinkel, H. A. W., Mullen, D., Meyer, G. D., Baert, K., & Carmichael, S. (2010) · Veterinary Research Communications · doi:10.1007/s11259-010-9348-7 · Cited by 147 · see citing works
Self-citationPrevalence and risk factors for canine obesity surveyed in veterinary practices in Beijing, China
Mao, J., Xia, Z., Chen, J., & Yu, J. (2013) · Preventive Veterinary Medicine · doi:10.1016/j.prevetmed.2013.08.012 · Cited by 140 · see citing works
Canine and feline obesity: A One Health perspective
Sandøe, P., Palmer, C., Corr, S., Astrup, A., & Bjørnvad, C. R. (2014) · Veterinary Record · doi:10.1136/vr.g7521 · Cited by 106 · see citing works
A systematic review of studies using pedometers as an intervention for musculoskeletal diseases
Mansi, S., Milosavljevic, S., Baxter, D. G., Tumilty, S., & Hendrick, P. A. (2014) · BMC Musculoskeletal Disorders · doi:10.1186/1471-2474-15-231 · Cited by 97 · see citing works
Summers, J. F., O'Neill, D. G., Church, D. B., Collins, L., Sargan, D. R., & Brodbelt, D. C. (2019) · BMC Veterinary Research · doi:10.1186/s12917-019-1902-0 · Cited by 91 · see citing works
Current and Future Issues in the Development of Spinal Agents for the Management of Pain
Yaksh, T. L., Fisher, C. J., Hockman, T. M., & Wiese, A. J. (2016) · Current Neuropharmacology · doi:10.2174/1570159x14666160307145542 · Cited by 73 · see citing works
The Responsibility of Veterinarians to Address Companion Animal Obesity
Kipperman, B. S., & German, A. J. (2018) · Animals · doi:10.3390/ani8090143 · Cited by 63 · see citing works
Effect of age at gonadectomy on the probability of dogs becoming overweight
Lefebvre, S. L., Yang, M., Wang, M., Elliott, D. A., Buff, P. R., & Lund, E. M. (2013) · Journal of the American Veterinary Medical Association · doi:10.2460/javma.243.2.236 · Cited by 57 · see citing works
Evaluating the benefits and risks of neutering dogs and cats.
McKenzie, B. A. (2010) · CABI Reviews · doi:10.1079/pavsnnr20105045 · Cited by 54 · see citing works
Nutritional Care for Aging Cats and Dogs
Laflamme, D. P. (2012) · Veterinary Clinics of North America Small Animal Practice · doi:10.1016/j.cvsm.2012.04.002 · Cited by 55 · see citing works
Obesity, Exercise and Orthopedic Disease
Frye, C. W., Shmalberg, J. W., & Wakshlag, J. J. (2016) · Veterinary Clinics of North America Small Animal Practice · doi:10.1016/j.cvsm.2016.04.006 · Cited by 54 · see citing works
Nielsen, M. B. M., Pedersen, T. R., Mouritzen, A., Vitger, A. D., Nielsen, L. N., Poulsen, H. H., & Miles, J. E. (2020) · PLoS ONE · doi:10.1371/journal.pone.0243819 · Cited by 44 · see citing works
McKenzie, B. A. (2022) · American Journal of Veterinary Research · doi:10.2460/ajvr.22.02.0027 · Cited by 38 · see citing works
Evaluation of gait-related variables in lean and obese dogs at a trot
Brady, R. B., Sidiropoulos, A. N., Bennett, H. J., Rider, P. M., Marcellin‐Little, D. J., & DeVita, P. (2013) · American Journal of Veterinary Research · doi:10.2460/ajvr.74.5.757 · Cited by 38 · see citing works
Venator, K. R., Frye, C. W., Gamble, L.-J., & Wakshlag, J. J. (2020) · Veterinary Medicine Research and Reports · doi:10.2147/vmrr.s238598 · Cited by 36 · see citing works
King, T. A. (2021) · Emerging Topics in Life Sciences · doi:10.1042/etls20200353 · Cited by 35 · see citing works
Factors associated with failure of dog's weight loss programmes
Porsani, M. Y. H., Teixeira, F. A., Amaral, A. R., Pedrinelli, V., de Oliveira, V. V., de Oliveira, A. G., Vendramini, T. H. A., & Brunetto, M. A. (2019) · Veterinary Medicine and Science · doi:10.1002/vms3.229 · Cited by 34 · see citing works
James, H. K., McDonnell, F., & Lewis, T. (2020) · Frontiers in Veterinary Science · doi:10.3389/fvets.2019.00490 · Cited by 33 · see citing works
Brazilian owners perception of the body condition score of dogs and cats
Teixeira, F. A., Queiroz, M. R., Oba, P. M., Olivindo, R. F. G., Ernandes, M. C., Duarte, C. N., Rentas, M. F., & Brunetto, M. A. (2020) · BMC Veterinary Research · doi:10.1186/s12917-020-02679-8 · Cited by 32 · see citing works
Hind limb kinematics during therapeutic exercises in dogs with osteoarthritis of the hip joints
Bockstahler, B. A., Prickler, B., Lewy, E., Holler, P. J., Vobornik, A., & Peham, C. (2012) · American Journal of Veterinary Research · doi:10.2460/ajvr.73.9.1371 · Cited by 32 · see citing works
Self-citationPhysiotherapeutic Strategies and Their Current Evidence for Canine Osteoarthritis
Mille, M. A., McClement, J., & Lauer, S. K. (2022) · Veterinary Sciences · doi:10.3390/vetsci10010002 · Cited by 36 · see citing works
Chiang, C., Villaverde, C., Chang, W.-C., Fascetti, A. J., & Larsen, J. A. (2022) · Topics in companion animal medicine · doi:10.1016/j.tcam.2022.100640 · Cited by 32 · see citing works
Canine and Feline Obesity Management
Shepherd, M. L. (2021) · Veterinary Clinics of North America Small Animal Practice · doi:10.1016/j.cvsm.2021.01.005 · Cited by 29 · see citing works
Prevalence of asymptomatic urinary tract infections in morbidly obese dogs
Wynn, S. G., Witzel, A. L., Bartges, J. W., Moyers, T. D., & Kirk, C. A. (2016) · PeerJ · doi:10.7717/peerj.1711 · Cited by 29 · see citing works
Proposed Canadian Consensus Guidelines on Osteoarthritis Treatment Based on OA-COAST Stages 1–4
Mosley, C., Edwards, T., Romano, L., Truchetti, G., Dunbar, L., Schiller, T., Gibson, T., Bruce, C., & Troncy, É. (2022) · Frontiers in Veterinary Science · doi:10.3389/fvets.2022.830098 · Cited by 28 · see citing works
de Velde, H. V., Janssens, G. P. J., Rochus, K., Duchateau, L., Scharek‐Tedin, L., Zentek, J., Nguyen, P., Cox, E., Buyse, J. G., Biourge, V. C., et al. (2012) · Veterinary Immunology and Immunopathology · doi:10.1016/j.vetimm.2012.12.011 · Cited by 25 · see citing works
Maniaki, E., Murrell, J. C., Langley-Hobbs, S. J., & Blackwell, E. J. (2021) · Journal of Feline Medicine and Surgery · doi:10.1177/1098612x21991456 · Cited by 24 · see citing works
Platelet-Rich Plasma as an Orthobiologic
Carr, B. J. (2022) · Veterinary Clinics of North America Small Animal Practice · doi:10.1016/j.cvsm.2022.02.005 · Cited by 24 · see citing works
Osteoarthritis in two marine mammals and 22 land mammals: learning from skeletal remains
Nganvongpanit, K., Soponteerakul, R., Kaewkumpai, P., Punyapornwithaya, V., Buddhachat, K., Nomsiri, R., Kaewmong, P., Kittiwatanawong, K., Chawangwongsanukun, R., Angkawanish, T., et al. (2017) · Journal of Anatomy · doi:10.1111/joa.12620 · Cited by 23 · see citing works
Gilbert, S., Langenbach, A., Marcellin‐Little, D. J., Pease, A. P., & Ru, H. (2019) · Veterinary Radiology & Ultrasound · doi:10.1111/vru.12718 · Cited by 22 · see citing works
Dobenecker, B., Reese, S., Jahn, W., Schunck, M., Hugenberg, J., Louton, H., & Oesser, S. (2018) · Journal of Animal Physiology and Animal Nutrition · doi:10.1111/jpn.12863 · Cited by 21 · see citing works
Flacke, G. L., Tkalčić, S., Steck, B., Warren, K., & Martin, G. B. (2016) · Zoo Biology · doi:10.1002/zoo.21336 · Cited by 20 · see citing works
Pamela Thomson, M., Santibáñez, R., Rodríguez-Salas, C., Flores-Yáñez, C., & Garrido, D. A. (2022) · PeerJ · doi:10.7717/peerj.12695 · Cited by 20 · see citing works
Moberg, F. S., Langhorn, R., Bertelsen, P. V., Pilegaard, L. M., Sørensen, T. M., Bjørnvad, C. R., Damborg, P., Kieler, I. N., & Jessen, L. R. (2019) · Journal of Feline Medicine and Surgery · doi:10.1177/1098612x19874141 · Cited by 20 · see citing works
Ruff, K., Kopp, K. F., Von Behrens, P., Lux, M., Mahn, M. M., & Back, M. (2016) · Veterinary Medicine Research and Reports · doi:10.2147/vmrr.s101842 · Cited by 18 · see citing works
Reid, J., Gildea, E., Davies, V., Thompson, J., & Scott, M. (2024) · Frontiers in Veterinary Science · doi:10.3389/fvets.2024.1395360 · Cited by 17 · see citing works
Modulation of inflammation and oxidative stress in canine chondrocytes
Dycus, D. L., Au, A. Y., Grzanna, M. W., Wardlaw, J. L., & Frondoza, C. G. (2013) · American Journal of Veterinary Research · doi:10.2460/ajvr.74.7.983 · Cited by 16 · see citing works
Schunck, M., Louton, H., & Oesser, S. (2017) · Open Journal of Animal Sciences · doi:10.4236/ojas.2017.73020 · Cited by 16 · see citing works
An across-breed validation study of 46 genetic markers in canine hip dysplasia
Mikkola, L., Kyöstilä, K., Donner, J., Lappalainen, A. K., Hytönen, M. K., Lohi, H., & Iivanainen, A. (2021) · BMC Genomics · doi:10.1186/s12864-021-07375-x · Cited by 15 · see citing works
Morelli, G., Patuzzi, I., Losasso, C., Ricci, A., Contiero, B., Andrighetto, I., & Ricci, R. (2022) · Scientific Reports · doi:10.1038/s41598-022-13270-6 · Cited by 13 · see citing works
Cardiac effect of short‐term experimental weight gain and loss in dogs
Pelosi, A., Rosenstein, D. S., Abood, S. K., & Olivier, B. (2013) · Veterinary Record · doi:10.1136/vr.100178 · Cited by 16 · see citing works
Translational animal models using veterinary patients – An example of canine osteoarthritis (OA)
Vainio, O. (2012) · Scandinavian Journal of Pain · doi:10.1016/j.sjpain.2011.11.007 · Cited by 15 · see citing works
Impacts of Adiposity on Exercise Performance in Horses
Pratt-Phillips, S. E., & Munjizun, A. (2023) · Animals · doi:10.3390/ani13040666 · Cited by 13 · see citing works
Demographic factors associated with joint supplement use in dogs from the Dog Aging Project
Hoffman, J. M., Tolbert, M. K., & Promislow, D. (2022) · Frontiers in Veterinary Science · doi:10.3389/fvets.2022.906521 · Cited by 12 · see citing works
Min, Y., Ahn, D., Truong, T. M. T., Kim, M., Heo, Y., Jee, Y., Son, Y., & Kang, I. (2022) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2022.109223 · Cited by 12 · see citing works
Musolino, V., Marrelli, M., Perri, M. R., Palermo, M., Gliozzi, M., Mollace, V., & Conforti, F. (2022) · Molecules · doi:10.3390/molecules28010032 · Cited by 12 · see citing works
Knee Joint Osteoarthritis in Overweight Cats: The Clinical and Radiographic Findings
Bonecka, J., Skibniewski, M., Zep, P., & Domino, M. (2023) · Animals · doi:10.3390/ani13152427 · Cited by 12 · see citing works
Traughber, Z. T., Detweiler, K. B., Price, A. K., Knap, K. E., Harper, T. A. M., Swanson, K. S., & de Godoy, M. R. C. (2021) · American Journal of Veterinary Research · doi:10.2460/ajvr.82.10.787 · Cited by 12 · see citing works
Janke, N., Coe, J. B., Bernardo, T. M., Dewey, C. E., & STONE, E. A. (2022) · Veterinary Record · doi:10.1002/vetr.1378 · Cited by 12 · see citing works
Krasuska, M., & Webb, T. L. (2018) · Preventive Veterinary Medicine · doi:10.1016/j.prevetmed.2018.08.016 · Cited by 11 · see citing works
Söder, J., Wernersson, S., Höglund, K., Hagman, R., Lindåse, S. S., & Dicksved, J. (2022) · Acta veterinaria Scandinavica · doi:10.1186/s13028-022-00628-z · Cited by 11 · see citing works
Age-Associated Cartilage Degeneration of the Canine Humeral Head
Craig, L. E., & Reed, A. (2012) · Veterinary Pathology · doi:10.1177/0300985812452584 · Cited by 11 · see citing works
Pan, Y., Spears, J. K., Xu, H., & Bhatnagar, S. (2023) · Journal of Animal Science · doi:10.1093/jas/skad183 · Cited by 10 · see citing works
Body composition of medium to giant breed dogs with or without cranial cruciate ligament disease
Santarossa, A., Gibson, T. W. G., Kerr, C. L., Monteith, G. J., Durzi, T., Gowland, S., & Verbrugghe, A. (2020) · Veterinary Surgery · doi:10.1111/vsu.13434 · Cited by 10 · see citing works
Skeletal Pathology of Farm-Reared Obese Juvenile Blue Foxes (Vulpes lagopus)
Mustonen, A., Lawier, D., Ahola, L., Koistinen, T., Jalkanen, L., Mononen, J., Lamidi, M., & Nieminen, P. (2017) · Journal of Veterinary Anatomy · doi:10.21608/jva.2017.45445 · Cited by 10 · see citing works
Haddad, K. K. (2024) · Animals · doi:10.3390/ani14050740 · Cited by 9 · see citing works
Bound, N. J., Upjohn, M. J., Jackson, S., & BAINES, S. J. (2011) · Veterinary Record · doi:10.1136/vr.d1021 · Cited by 9 · see citing works
Slavov, E., Georgiev, I. P., Dzhelebov, P., Kanelov, I., Andonova, M., Georgieva, T. M., & Dimitrova, S. (2010) · Veterinary Research Communications · doi:10.1007/s11259-010-9345-x · Cited by 9 · see citing works
Torres, M., Damiá, E., Romero, A. D., Peláez, P., de Miguel, L., Chicharro, D., Carrillo, J. M., Rubio, M., & Sopena, J. J. (2023) · Frontiers in Veterinary Science · doi:10.3389/fvets.2023.1131666 · Cited by 11 · see citing works
Yuma, P., Fowler, J., Duerr, F. M., Kogan, L. R., Stockman, J. A., Graham, D. J., & Duncan, C. (2018) · Topics in companion animal medicine · doi:10.1053/j.tcam.2018.11.002 · Cited by 8 · see citing works
Regenerative Medicine and Rehabilitation Therapy in the Canine
Carr, B. J. (2023) · Veterinary Clinics of North America Small Animal Practice · doi:10.1016/j.cvsm.2023.02.011 · Cited by 6 · see citing works
The Role of Chondroprotectants, Nutraceuticals, and Nutrition in Rehabilitation
Raditic, D., & Bartges, J. W. (2013) · Elsevier eBooks · doi:10.1016/b978-1-4377-0309-2.00015-6 · Cited by 6 · see citing works
Macrı̀, F., Cicero, L. L., Angileri, V., Biondi, V., Miele, P., Scaletta, L., Costa, G. L., Cassata, G., & Pietro, S. D. (2021) · BMC Veterinary Research · doi:10.1186/s12917-021-02899-6 · Cited by 6 · see citing works
Collagen Hydrolysates as Nutritional Support in Canine Osteoarthritis: A Narrative Review
Blees, N. R., Teunissen, M., Dobenecker, B., Prawitt, J., Tryfonidou, M. A., & Corbee, R. J. (2024) · Journal of Animal Physiology and Animal Nutrition · doi:10.1111/jpn.14076 · Cited by 5 · see citing works
Buttin, P., Santoro, V., Agbalé, M., Goin, B., Cachon, T., Viguier, É., & Martini, F. M. (2022) · Open Veterinary Journal · doi:10.5455/ovj.2022.v12.i3.11 · Cited by 5 · see citing works
Lloyd, I., Furtado, T., German, A. J., Watkins, F., Christley, R., & Westgarth, C. (2023) · Anthrozoös · doi:10.1080/08927936.2023.2166714 · Cited by 5 · see citing works
Murrell, J. C., Grandemange, E., Woehrlé, F., Menard, J., & White, K. (2014) · Open Journal of Veterinary Medicine · doi:10.4236/ojvm.2014.45010 · Cited by 5 · see citing works
Impact of feeding method on overall activity of indoor, client‐owned dogs
Su, D. K., Murphy, M., Hand, A., Zhu, X., & Witzel-Rollins, A. (2019) · Journal of Small Animal Practice · doi:10.1111/jsap.13003 · Cited by 5 · see citing works
Ragetly, G. R., Martins, Â., Ciprian Andrei, O. B. E. R., Boiocchi, S., & Nicolas, C. S. (2025) · Frontiers in Veterinary Science · doi:10.3389/fvets.2025.1561793 · Cited by 4 · see citing works
Khalil, E., Metwally, M., El-Shafey, A., Eshra, E. A., Imam, J., Hambolu, J. O., Onyeanusi, B. I., Ayo, J. O., Sulaiman, M., Nzalak, J. O., et al. (2017) · Journal of Veterinary Anatomy · doi:10.21608/jva.2017.36830 · Cited by 4 · see citing works
Physical Rehabilitation for Geriatric and Arthritic Patients
Marcellin‐Little, D. J., Levine, D. F., & Millis, D. L. (2013) · Elsevier eBooks · doi:10.1016/b978-1-4377-0309-2.00035-1 · Cited by 4 · see citing works
Torres, M., Damiá, E., Peláez, P., de Miguel, L., Cuervo, B., Cerón, J. M. C., Carrillo, J. M., Rubio, M., & Sopena, J. J. (2022) · Frontiers in Veterinary Science · doi:10.3389/fvets.2022.1057079 · Cited by 4 · see citing works
Osteoartrose de quadril em cães e gatos: Revisão
Lamounier, A. R., Soares, J. D. O., Lage, M. H. H., & de Melo, V. S. C. (2023) · PubVet · doi:10.31533/pubvet.v17n02a1347 · Cited by 3 · see citing works
Carrera, A. L. C., Minto, B. W., Malard, P. F., & Brunel, H. D. S. S. (2023) · Veterinary Medicine International · doi:10.1155/2023/8819506 · Cited by 3 · see citing works
The General and Systemic Consequences of Obesity in Cats and Dogs
Masood, W. (2024) · Veterinary Integrative Sciences · doi:10.12982/vis.2024.020 · Cited by 3 · see citing works
Moreau, M., & Troncy, É. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-805186-3.00025-4 · Cited by 3 · see citing works
Moncunill-Solé, B., Arzi, B., Filliquist, B., Vapniarsky, N., Zavodovskaya, R., & Angelone, C. (2023) · Palaeoworld · doi:10.1016/j.palwor.2023.03.004 · Cited by 2 · see citing works
Ponn, P. C., Tipold, A., Goericke‐Pesch, S., & Volk, A. V. (2025) · Animals · doi:10.3390/ani15070933 · Cited by 2 · see citing works
From functional ingredients to bioactive compounds: a review of their role in commercial pet food
Guo, X., Farooq, N., Liu, H., Xie, X., Zhu, Z., & Li, L. (2026) · Veterinary Research Communications · doi:10.1007/s11259-026-11178-4 · Cited by 2 · see citing works
Clinical Guide to Obesity and Nonherbal Nutraceuticals in Canine Orthopedic Conditions
Ratsch, B. E., Levine, D. F., & Wakshlag, J. J. (2022) · Veterinary Clinics of North America Small Animal Practice · doi:10.1016/j.cvsm.2022.03.002 · Cited by 2 · see citing works
Kim, H.-W., Kim, Y., Kim, W. K., Kang, K.-W., & Kang, B. (2024) · American Journal of Veterinary Research · doi:10.2460/ajvr.24.07.0190 · Cited by 2 · see citing works
イヌにおける CT 撮影により得られた体脂肪評価と BCS 評価の相関
神田, 鉄., 前田, 憲., 亜弥乃, 井., 和紀, 柴., 千晴, 野., 山本達也, Murao, N., 加計, 悟., 古本, 佳., & 古川, 敏. (2013) · ペット栄養学会誌 · doi:10.11266/jpan.16.1 · Cited by 2 · see citing works
Energy Requirements for Growth in the Norfolk Terrier
Bradley, S., Alexander, J. E., Haydock, R., Bakke, A. M., & Watson, P. (2021) · Animals · doi:10.3390/ani11051380 · Cited by 2 · see citing works
Nutritional Management of Orthopedic Diseases
Hazewinkel, H. A. W. (2012) · doi:10.1002/9781118785669.ch10 · Cited by 2 · see citing works
Chronic Pain Management for the Companion Animal
Norkus, C. L. (2014) · doi:10.1002/9781119421436.ch9 · Cited by 2 · see citing works
Intra-Articular Administration of a Synthetic Lubricin in Canine Stifles
Hayashi, K., Bourgeois, A., Lopez, D. J., Caserto, B. G., Berthelsen, E. S., Krotscheck, U., Reesink, H. L., Kim, S.-Y., & Putnam, D. A. (2021) · Veterinary and Comparative Orthopaedics and Traumatology · doi:10.1055/s-0041-1736189 · Cited by 1 · see citing works
Morros-Nuevo, A., Salt, C., Pavey, J., Wainwright, J. F., Dittmann, M. T., Keep, B., Wallis, N. J., & Raffan, E. (2026) · BMC Veterinary Research · doi:10.1186/s12917-025-04990-8 · Cited by 1 · see citing works
RISK TO ACQUIRING TOXOPLASMOSIS HUMAN TO HUMAN
Rosales-Aguilar, M., & Sánchez-Díaz, M. D. L. R. (2022) · doi:10.22533/at.ed.69822150217 · Cited by 1 · see citing works
Cánovas, F., Planes-Muñoz, D., Zurbano, M. J., Messia, P., & Vasallo-Morillas, M. I. (2023) · World Journal of Food Science and Technology · doi:10.11648/j.wjfst.20230703.11 · Cited by 1 · see citing works
Insights into the Prevalence of Diabetes Mellitus in Dogs in Pakistan
Khalid, A., Ahmad, B., Waheed, M. A., Azhar, R., Ashfaq, K., Khan, A. A., Ahmed, H. A., Sana, M. A., Kharl, R. B., & Alvi, M. A. (2025) · Indus journal of bioscience research. · doi:10.70749/ijbr.v3i3.838 · Cited by 1 · see citing works
Piantedosi, D., Giada, M., Musco, N., Carlo, S., della Valle, M. F., Francesco, P., Saad, N., Giulia, A., Maria, F., Lombardi, P., et al. (2025) · BMC Veterinary Research · doi:10.1186/s12917-025-04946-y · Cited by 1 · see citing works
Stem Cell Veterinary Medicines as Signs Pointing Towards Successful Human Stem Cell Therapeutics
Vertès, A. A. (2015) · Wiley eBooks · doi:10.1002/9781118846193.ch15 · Cited by 1 · see citing works
Literatuurstudie voercontrole vleeskuikenouderdieren
van Emous, R. (2020) · doi:10.18174/539675 · Cited by 1 · see citing works
Nutritional Management of Orthopedic Diseases
Hazewinkel, H. A. W. (2023) · doi:10.1002/9781119375241.ch10 · Cited by 1 · see citing works
Budsberg, S. C., & Hinson, W. D. (2024) · doi:10.1002/9781119830306.ch71 · Cited by 1 · see citing works
Non‐Pharmacologic Management of Pain
Wright, B. D. (2024) · doi:10.1002/9781119830306.ch49 · Cited by 1 · see citing works
- Authors
- Bockstahler, B. A., Hulse, D. A., Carmichael, S., & Marshall, W. G.
- Affiliations
- University of Veterinary Medicine Vienna (AT)
- Texas A&M University (US)
- University of Glasgow (GB)
- ORCID
- Bockstahler, B. A.
- Venue
- Veterinary and Comparative Orthopaedics and Traumatology
- Publisher
- Georg Thieme Verlag KG
- Published
- 2009
- Volume
- 22
- Issue
- 05
- Pages
- 339-345
- ISSN
- 0932-0814 (ISSN-L)
- 2567-6911
- OpenAlex
- W2111477529
- Cited by
- 134
- References
- 41
- Citations by year
- 2026: 7 · 2025: 6 · 2024: 8 · 2023: 13 · 2022: 27 · 2021: 10 · 2020: 7 · 2019: 6 · 2018: 4 · 2017: 6 · 2016: 6 · 2015: 5 · 2014: 5 · 2013: 11 · 2012: 6
- FWCI
- 0.95
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Veterinary and Comparative Orthopaedics and Traumatology (publishedVersion)
- PubMed (publishedVersion)
- Open Research (University of Surrey) (submittedVersion)
- ENLIGHTEN (Jurnal Bimbingan dan Konseling Islam) (submittedVersion)
- Surrey Research Insight Open Access (The University of Surrey) (submittedVersion)
- Topics
- Health Sciences › Veterinary › Small Animals › Veterinary Orthopedics and Neurology
- Health Sciences › Veterinary › Small Animals › Veterinary Medicine and Surgery
- Health Sciences › Medicine › Rheumatology › Osteoarthritis Treatment and Mechanisms
- Keywords
- canine osteoarthritis, canine obesity, weight loss, obesity treatment, obesity prevention, hip dysplasia, knee osteoarthritis, overweight dogs
- MeSH terms
- Animals, Dog Diseases, Dogs, Obesity, Osteoarthritis
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review