The DOI matches its Crossref record; 74 of the 74 references it cites were found in a registry or an index.
Emerging roles of lactic acid bacteria in protection against colorectal cancer
Open accessAbstract
Colorectal cancer (CRC) is the third leading cause of cancer deaths worldwide and the fourth most common cancer diagnosed among men and women in the United States. Considering the risk factors of CRC, dietary therapy has become one of the most effective approaches in reducing CRC morbidity and mortality. The use of probiotics is increasing in popularity for both the prevention and treatment of a variety of diseases. As the most common types of microbes used as probiotics, lactic acid bacteria (LAB) are comprised of an ecologically diverse group of microorganisms united by formation of lactic acid as the primary metabolite of sugar metabolism. LAB have been successfully used in managing diarrhea, food allergies, and inflammatory bowel disease. LAB also demonstrated a host of properties in preventing colorectal cancer development by inhibiting initiation or progression through multiple pathways. In this review, we discuss recent insights into cellular and molecular mechanisms of LAB in CRC prevention including apoptosis, antioxidant DNA damages, immune responses, and epigenetics. The emerging experimental findings from clinical trials as well as the proposed mechanisms of gut microbiota in carcinogenesis will also be briefly discussed.
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Cited by
Colorectal Carcinoma: A General Overview and Future Perspectives in Colorectal Cancer
Mármol, I., Sánchez-de-Diego, C., Pradilla Dieste, A., Cerrada, E., & Rodriguez Yoldi, M. (2017) · International Journal of Molecular Sciences · doi:10.3390/ijms18010197 · Cited by 1,525
Tiptiri-Kourpeti, A., Spyridopoulou, K., Santarmaki, V., Aindelis, G., Tompoulidou, E., Lamprianidou, E. E., Saxami, G., Ypsilantis, P., Lampri, E. S., Simopoulos, C., et al. (2016) · PLOS ONE · doi:10.1371/journal.pone.0147960 · Cited by 319
The Role of Probiotics in Cancer Prevention
Śliżewska, K., Markowiak-Kopeć, P., & Śliżewska, W. (2020) · Cancers · doi:10.3390/cancers13010020 · Cited by 282
Dietary Emulsifier–Induced Low-Grade Inflammation Promotes Colon Carcinogenesis
Viennois, E., Merlin, D., Gewirtz, A. T., & Chassaing, B. (2017) · Cancer Research · doi:10.1158/0008-5472.can-16-1359 · Cited by 268
Obesity and cancer: existing and new hypotheses for a causal connection
Stone, T. W., McPherson, M., & Gail Darlington, L. (2018) · eBioMedicine · doi:10.1016/j.ebiom.2018.02.022 · Cited by 262
Metadata
- Authors
- Zhong, L.
- Venue
- World Journal of Gastroenterology
- Publisher
- Baishideng Publishing Group Inc.
- Published
- 2014
- Volume
- 20
- Issue
- 24
- Pages
- 7878
- ISSN
- 1007-9327 (ISSN-L)
- OpenAlex
- W2095416491
- Cited by
- 256
- References
- 74
- FWCI
- 25.94
- Type
- journal article
- Language
- en
- Open access
- hybrid
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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