Immunogenicity and mechanisms impairing the response to vaccines in inflammatory bowel disease
Open accessAbstract
Inflammatory bowel disease (IBD) is an immunological disorder that is usually treated with immunosuppressive therapy, potentially leading to increases in vulnerability to infections. Although many infections can be prevented by vaccination, vaccination coverage in these patients in clinical practice is insufficient. Therefore, the seroprotection condition should be verified, even for routine vaccines, such as hepatitis B or pneumococcus. Response to vaccines in IBD patients is thought to be impaired due to the immunological alterations generated by the disease and to the immunomodulatory treatments. The immunogenicity of hepatitis B, influenza, and pneumococcal vaccines is impaired in IBD patients, whereas the response to papillomavirus vaccine seems similar to that observed in the healthy population. On the other hand, data on the immunogenicity of tetanus vaccine in IBD patients are conflicting. Studies assessing the response to measles-mumps-rubella, varicella, and herpes zoster vaccines in IBD patients are scarce. The cellular and molecular mechanisms responsible for the impairment of the response to vaccination in IBD patients are poorly understood. Studies aiming to assess the response to vaccines in IBD patients and to identify the mechanisms involved in their immunogenicity are warranted. A better understanding of the immune response, specifically to vaccines, in patients with immune-mediated diseases (such as IBD), is crucial when developing vaccines that trigger more potent immunologic responses.
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Reduced immunogenicity of HBV and influenza vaccines in IBD patients is thought to be influenced by this immunological impairment, but underlying pathomechanism remains to be elucidated.
“This is thought to influence the reduced immunogenicity of HBV and influenza vaccines in IBD patients, for which the underlying pathomechanism remains to be elucidated (Marín et al., 2015).”
From Viral Infections, the Microbiome, and Probiotics (2021) · cites this paper as Marín et al., 2015
IBD patients, either UC or CD, are at higher risk of viral infections and require specific antiviral care including sero-surveillance, vaccination and anti-infective therapies.
“IBD patients, either ulcerative colitis (UC) or Crohn’s disease (CD), are at higher risk of viral infections and therefore require specific antiviral care including sero-surveillance, vaccination and anti-infective therapies.”
From Viral Infections, the Microbiome, and Probiotics (2021) · cites this paper as Marín et al., 2015
Increased viral infection risk in IBD is due to immunological impairment induced by both pathophysiology and immuno-modulating medications.
“This increased risk is due to immunological impairment induced by both the pathophysiology of the disease and immuno-modulating medications (Marín et al., 2015; Magro et al., 2017).”
From Viral Infections, the Microbiome, and Probiotics (2021) · cites this paper as Marín et al., 2015
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Epidemiologic classification of human papillomavirus types associated with cervical cancer
Muñoz, N., Bosch, F. X., de Sanjosé, S., Herrero, R., Castellsagué, X., Shah, K. V., Snijders, P. J. F., & Meijer, C. J. L. M. (2003) · New England Journal of Medicine · doi:10.1056/nejmoa021641 · Cited by 6,249 · see citing works
Fiore, A. E., Shay, D. K., Broder, K., Iskander, J. K., Uyeki, T. M., Mootrey, G., Bresee, J. S., & Cox, N. S. (2001) · PsycEXTRA Dataset · doi:10.1037/e548312006-001 · Cited by 5,006 · see citing works
Franke, A., McGovern, D. P. B., Barrett, J. C., Wang, K., Radford-Smith, G. L., Ahmad, T., Lees, C. W., Balschun, T., Lee, J., Roberts, R., et al. (2010) · Nature Genetics · doi:10.1038/ng.717 · Cited by 2,520 · see citing works
A Vaccine to Prevent Herpes Zoster and Postherpetic Neuralgia in Older Adults
Oxman, M. N., Levin, M. J., Johnson, G. R., Schmader, K. E., Straus, S. E., Gelb, L. D., Arbeit, R. D., Simberkoff, M. S., Gershon, A. A., Davis, L. E., et al. (2005) · New England Journal of Medicine · doi:10.1056/nejmoa051016 · Cited by 2,412 · see citing works
Harper, D. M., Franco, E. L., Wheeler, C. M., Moscicki, A., Romanowski, B., Roteli-Martins, C. M., Jenkins, D., Schuind, A., Clemens, S. A. C., & Dubin, G. O. (2006) · The Lancet · doi:10.1016/s0140-6736(06)68439-0 · Cited by 1,629 · see citing works
Villa, L. L., Costa, R. L. R., Petta, C. A., de Andrade, R. P., Ault, K. A., Giuliano, A. R., Wheeler, C. M., Koutsky, L. A., Malm, C., Lehtinen, M., et al. (2005) · The Lancet Oncology · doi:10.1016/s1470-2045(05)70101-7 · Cited by 1,593 · see citing works
Rahier, J. F., Ben-Horin, S., Chowers, Y., Conlon, C., Munter, P. D., D’Haens, G., Domènech, E., Eliakim, R., Eser, A., Frater, J., et al. (2009) · Journal of Crohn s and Colitis · doi:10.1016/j.crohns.2009.02.010 · Cited by 1,247 · see citing works
Mast, E. E., Weinbaum, C. M., Fiore, A. E., Alter, M. J., Bell, B. P., Finelli, L., Rodewald, L. E., Douglas, J. M., Janssen, R. S., & Ward, J. W. (2006) · PubMed · Cited by 1,129 · see citing works
Prevention of Varicella: Recommendations of the Advisory Committee on Immunization Practices (ACIP)
Marin, M., Güriş, D., Chaves, S. S., Schmid, S., & Seward, J. F. (1996) · PsycEXTRA Dataset · doi:10.1037/e547262006-001 · Cited by 1,077 · see citing works
Harpaz, R., Ortega‐Sanchez, I. R., & Seward, J. F. (2008) · PubMed · Cited by 1,018 · see citing works
Rahier, J., Magro, F., Abreu, C., Armuzzi, A., Ben‐Horin, S., Chowers, Y., Cottone, M., de Ridder, L., Doherty, G. A., Ehehalt, R., et al. (2014) · Journal of Crohn s and Colitis · doi:10.1016/j.crohns.2013.12.013 · Cited by 925 · see citing works
Prevention and Control of Influenza
(1985) · Annals of Internal Medicine · doi:10.7326/0003-4819-103-4-560 · Cited by 809 · see citing works
Krützmann, S. A.-C., Rosado, M. M., Weber, H., Germing, U., Tournilhac, O., Peter, H., Berner, R., Peters, A. M. J., Boehm, T. L. J., Plebani, A., et al. (2003) · The Journal of Experimental Medicine · doi:10.1084/jem.20022020 · Cited by 678 · see citing works
Human papillomavirus and cancer: the epidemiological evidence
Muñóz, N. (2000) · Journal of Clinical Virology · doi:10.1016/s1386-6532(00)00125-6 · Cited by 597 · see citing works
Recent Insights Into the Genetics of Inflammatory Bowel Disease
Cho, J. H., & Brant, S. R. (2011) · Gastroenterology · doi:10.1053/j.gastro.2011.02.046 · Cited by 424 · see citing works
Patients with Inflammatory Bowel Disease Are at Risk for Vaccine-Preventable Illnesses
MELMED, G. Y., Ippoliti, A., Papadakis, K. A., Tran, T. T., Birt, J. L., Lee, S. K., Frenck, R. W., Targan, S. R., & Vasiliauskas, E. A. (2006) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2006.00646.x · Cited by 326 · see citing works
Zhang, J., Xie, F., Delzell, E., Chen, L., Winthrop, K. L., Lewis, J. D., Saag, K. G., Baddley, J. W., & Curtis, J. R. (2012) · JAMA · doi:10.1001/jama.2012.7304 · Cited by 283 · see citing works
The loss of IgM memory B cells correlates with clinical disease in common variable immunodeficiency
Carsetti, R., Rosado, M. M., Donnanno, S., Guazzi, V., Soresina, A., Meini, A., Plebani, A., Aiuti, F., & Quinti, I. (2005) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2004.10.048 · Cited by 261 · see citing works
Guidelines for Immunizations in Patients With Inflammatory Bowel Disease
Sands, B. E., Cuffari, C., Katz, J., Kugathasan, S., Onken, J. E., VITEK, C. R., & Orenstein, W. A. (2004) · Inflammatory Bowel Diseases · doi:10.1097/00054725-200409000-00028 · Cited by 217 · see citing works
Hepatitis B vaccine – do we need boosters?
Banatvala, J. E., & Damme, P. V. (2003) · Journal of Viral Hepatitis · doi:10.1046/j.1365-2893.2003.00400.x · Cited by 207 · see citing works
MELMED, G. Y., Agarwal, N., Frenck, R. W., Ippoliti, A. F., Ibanez, P., Papadakis, K. A., Simpson, P., Barolet-Garcia, C., Ward, J., Targan, S. R., et al. (2009) · The American Journal of Gastroenterology · doi:10.1038/ajg.2009.523 · Cited by 206 · see citing works
Respiratory viruses and chronic rejection in lung transplant recipients
Billings, J. L. (2002) · The Journal of Heart and Lung Transplantation · doi:10.1016/s1053-2498(01)00405-3 · Cited by 198 · see citing works
Loras, C., Gisbert, J. P., Mínguez, M., Merino, O., Bujanda, L., Saro, C. M., Domènech, E., Barrio, J., Andreu, M. G., Ordás, Í., et al. (2010) · Gut · doi:10.1136/gut.2010.208413 · Cited by 188 · see citing works
A Practical Guide to Vaccinating the Inflammatory Bowel Disease Patient
Wasan, S. K., Baker, S. E., Skolnik, P. R., & Farraye, F. A. (2010) · The American Journal of Gastroenterology · doi:10.1038/ajg.2009.733 · Cited by 179 · see citing works
Opportunistic infections in patients with inflammatory bowel disease: prevention and diagnosis
Viget, N. B., Vernier-Massouille, G., Salmon, D., Yazdanpanah, Y., & Jf, C. (2008) · Gut · doi:10.1136/gut.2006.114660 · Cited by 179 · see citing works
Fiorino, G., Peyrin‐Biroulet, L., Naccarato, P., Szabó, H., Sociale, O. R., Vetrano, S., Fries, W., Montanelli, A., Repici, A., Malesci, A., et al. (2011) · Inflammatory Bowel Diseases · doi:10.1002/ibd.21800 · Cited by 177 · see citing works
Gelinck, L. B. S., van der Bijl, A. E., BEYER, W. E. P., Visser, L. G., Huizinga, T. W. J., van Hogezand, R. A., Rimmelzwaan, G. F., & Kroon, F. P. (2007) · Annals of the Rheumatic Diseases · doi:10.1136/ard.2007.077552 · Cited by 175 · see citing works
Immune Response to Influenza Vaccine in Pediatric Patients With Inflammatory Bowel Disease
Mamula, P., Markowitz, J. E., Piccoli, D. A., Klimov, A. I., Cohen, L. J., & Baldassano, R. N. (2007) · Clinical Gastroenterology and Hepatology · doi:10.1016/j.cgh.2007.02.035 · Cited by 175 · see citing works
Impaired Immune Responses and Antigen-Specific Memory CD4+ T Cells in Hemodialysis Patients
Litjens, N. H. R., Huisman, M., van den Dorpel, M., & Betjes, M. G. H. (2008) · Journal of the American Society of Nephrology · doi:10.1681/asn.2007090971 · Cited by 171 · see citing works
Hollinger, F. B. (1989) · The American Journal of Medicine · doi:10.1016/0002-9343(89)90530-5 · Cited by 160 · see citing works
Vaccinating the inflammatory bowel disease patient: Deficiencies in gastroenterologists knowledge
Wasan, S. K., Coukos, J. A., & Farraye, F. A. (2011) · Inflammatory Bowel Diseases · doi:10.1002/ibd.21667 · Cited by 159 · see citing works
Immune Response to Influenza Vaccine in Children With Inflammatory Bowel Disease
Lu, Y., Jacobson, D. L., Ashworth, L. A., Grand, R. J., Meyer, A. L., McNeal, M., Gregas, M., Burchett, S. K., & Bousvaros, A. (2009) · The American Journal of Gastroenterology · doi:10.1038/ajg.2008.120 · Cited by 149 · see citing works
Gisbert, J. P., Villagrasa, J. R., Rodríguez-Nogueiras, A., & Chaparro, M. (2012) · The American Journal of Gastroenterology · doi:10.1038/ajg.2012.79 · Cited by 147 · see citing works
Hepatitis B vaccines: assessment of the seroprotective efficacy of two recombinant DNA vaccines
Coates, T., Wilson, R., Patrick, G., André, F., & Watson, V. (2001) · Clinical Therapeutics · doi:10.1016/s0149-2918(01)80044-8 · Cited by 147 · see citing works
Picco, M. F. (2010) · Yearbook of Gastroenterology · doi:10.1016/s0739-5930(10)79460-5 · Cited by 135 · see citing works
Hospitalization Attributable to Influenza and Other Viral Respiratory Illnesses in Canadian Children
Schanzer, D. L., Langley, J. M., & Tam, T. W. S. (2006) · The Pediatric Infectious Disease Journal · doi:10.1097/01.inf.0000232632.86800.8c · Cited by 130 · see citing works
Anti-TNF treatment blocks the induction of T cell-dependent humoral responses
FrancoSalinas, G., Rycke, L. D., Barendregt, B. H., Paramarta, J. E., Hreggvidstdottir, H., Cantaert, T., van der Burg, M., Tak, P. P., & Baeten, D. (2012) · Annals of the Rheumatic Diseases · doi:10.1136/annrheumdis-2011-201270 · Cited by 116 · see citing works
Immunogenetics of seasonal influenza vaccine response
Poland, G. A., Ovsyannikova, I. G., & Jacobson, R. M. (2008) · Vaccine · doi:10.1016/j.vaccine.2008.07.065 · Cited by 114 · see citing works
Gisbert, J. P., Chaparro, M., & Esteve, M. (2011) · Alimentary Pharmacology & Therapeutics · doi:10.1111/j.1365-2036.2010.04570.x · Cited by 113 · see citing works
MELMED, G. Y. (2009) · Inflammatory Bowel Diseases · doi:10.1002/ibd.20943 · Cited by 111 · see citing works
Hassan, I. A., Chopra, R., Swindell, R., & Mutton, K. J. (2003) · Bone Marrow Transplantation · doi:10.1038/sj.bmt.1704048 · Cited by 102 · see citing works
Sabatino, A. D., Rosado, M. M., Ciccocioppo, R., Cazzola, P., Morera, R., Corazza, G. R., & Carsetti, R. (2005) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2005.41939.x · Cited by 102 · see citing works
Gisbert, J. P., Menchen, L. A., García-Sánchez, V., Marín, I., Villagrasa, J. R., & Chaparro, M. (2012) · Alimentary Pharmacology & Therapeutics · doi:10.1111/j.1365-2036.2012.05110.x · Cited by 91 · see citing works
Role of influenza and other respiratory viruses in admissions of adults to Canadian hospitals
Schanzer, D. L., Langley, J. M., & Tam, T. W. S. (2008) · Influenza and Other Respiratory Viruses · doi:10.1111/j.1750-2659.2008.00035.x · Cited by 85 · see citing works
Jacobson, D. L., Bousvaros, A., Ashworth, L. A., Carey, R. G., Shrier, L. A., Burchett, S. K., Renna, H., & Lu, Y. (2013) · Inflammatory Bowel Diseases · doi:10.1097/mib.0b013e318281341b · Cited by 82 · see citing works
Immunogenicity and safety of influenza vaccination in children with inflammatory bowel disease
deBruyn, J. C. C., Hilsden, R. J., Fonseca, K., Russell, M. L., Kaplan, G. G., Vanderkooi, O. G., & Wrobel, I. T. (2011) · Inflammatory Bowel Diseases · doi:10.1002/ibd.21706 · Cited by 77 · see citing works
Altunöz, M. E., Şenateş, E., Yeşıl, A., Çalhan, T., & Övünç, A. O. K. (2011) · Digestive Diseases and Sciences · doi:10.1007/s10620-011-1980-8 · Cited by 77 · see citing works
Defect in Th1-Like Cells of Nonresponders to Hepatitis B Vaccine
Chedid, M. G., Deulofeut, H., Yunis, D. E., Lara-Marquez, M. L., Salazar, M., Deulofeut, R., Awdeh, Z., Alper, C. A., & Yunis, E. J. (1997) · Human Immunology · doi:10.1016/s0198-8859(97)00209-7 · Cited by 62 · see citing works
Shokrgozar, M. A., & Shokri, F. (2001) · Immunology · doi:10.1046/j.1365-2567.2001.01273.x · Cited by 61 · see citing works
Pérez, L. V., Camacho, F. G., Sánchez, V. G., Flores, E. I., Molina, L. C., Ruiz, A. C., Juanena, L. L. C., & Vega, J. F. D. D. (2009) · Medicina Clínica · doi:10.1016/j.medcli.2008.07.013 · Cited by 60 · see citing works
Population-based case-control study of measles, mumps, and rubella and inflammatory bowel disease
Bernstein, C. N., Rawsthorne, P. E., & Blanchard, J. (2007) · Inflammatory Bowel Diseases · doi:10.1002/ibd.20089 · Cited by 56 · see citing works
Loras, C., Gisbert, J. P., Saro, M. C. S., Piqueras, M., Sánchez-Montes, C., Barrio, J., Ordás, Í., Montserrat, A., Ferreiro, R., Zabana, Y., et al. (2014) · Journal of Crohn s and Colitis · doi:10.1016/j.crohns.2014.06.009 · Cited by 55 · see citing works
Yao, Z. Q., & Moorman, J. P. (2013) · Archivum Immunologiae et Therapiae Experimentalis · doi:10.1007/s00005-013-0219-0 · Cited by 48 · see citing works
Vaccination Coverage in Immunosuppressed Patients
Teich, N., Klugmann, T., Tiedemann, A., Holler, B., Mössner, J., Liebetrau, A., & Schiefke, I. (2011) · Deutsches Ärzteblatt international · doi:10.3238/arztebl.2011.0105 · Cited by 48 · see citing works
Leggat, D. J., Thompson, R. S., Khaskhely, N. M., Iyer, A. S., & Westerink, M. A. J. (2013) · The Journal of Infectious Diseases · doi:10.1093/infdis/jit139 · Cited by 43 · see citing works
Leggat, D. J., Khaskhely, N. M., Iyer, A. S., Mosakowski, J., Thompson, R. S., Weinandy, J. D., & Westerink, M. A. J. (2013) · Vaccine · doi:10.1016/j.vaccine.2013.07.030 · Cited by 39 · see citing works
Stevens, R. H., Oliver, M., Brogan, M., Heiserodt, J., & Targan, S. R. (1985) · Gastroenterology · doi:10.1016/0016-5085(85)90011-3 · Cited by 38 · see citing works
Crawford, N. W., Catto‐Smith, A. G., Oliver, M. R., Cameron, D. J. S., & Buttery, J. P. (2011) · BMC Gastroenterology · doi:10.1186/1471-230x-11-87 · Cited by 35 · see citing works
Cowan, M. L., Chon, W. J., Desai, A., Andrews, S. F., Bai, Y., Veguilla, V., Katz, J. M., Josephson, M. A., Wilson, P. C., Sciammas, R., et al. (2013) · Transplantation · doi:10.1097/01.tp.0000438024.10375.2d · Cited by 34 · see citing works
Nielsen, H. J., Mortensen, T., Holten-Andersen, M., Brünner, N., Sørensen, S., & Rask-Madsen, J. (2001) · Scandinavian Journal of Gastroenterology · doi:10.1080/003655201750074537 · Cited by 31 · see citing works
Splenic function and IgM-memory B cells in Crohnʼs disease patients treated with infliximab
Sabatino, A. D., Rosado, M. M., Cazzola, P., Biancheri, P., Tinozzi, F. P., Laera, M. R., Cantoro, L., Vanoli, A., Carsetti, R., & Corazza, G. R. (2008) · Inflammatory Bowel Diseases · doi:10.1002/ibd.20374 · Cited by 31 · see citing works
Albarrán, B., Goncalves, L., Salmen, S., Borges, L., Fields, H. A., Sóyano, A., Montes, H., & Berrueta, L. (2005) · Apmis · doi:10.1111/j.1600-0463.2005.apm_191.x · Cited by 29 · see citing works
Brogan, M., Shanahan, F., Oliver, M., Stevens, R. H., & Targan, S. R. (1987) · PubMed · Cited by 26 · see citing works
Pneumococcal vaccination in adults: recommendations, trends, and prospects.
Targonski, P. V., & Poland, G. A. (2007) · Cleveland Clinic Journal of Medicine · doi:10.3949/ccjm.74.6.401 · Cited by 23 · see citing works
Immunoglobulin M memory B cell decrease in inflammatory bowel disease.
Sabatino, A. D., Carsetti, R., Rosado, M. M., Ciccocioppo, R., Cazzola, P., Morera, R., Tinozzi, F. P., Tinozzi, S., & Corazza, G. R. (2004) · PubMed · Cited by 19 · see citing works
Good response to HBsAg vaccine in dialysis patients is associated with high CD4+/CD8+ ratio
Sarı, F., & Taşkapan, H. (2011) · International Urology and Nephrology · doi:10.1007/s11255-011-0043-6 · Cited by 18 · see citing works
Armstrong, K. E., Bush, H., Collins, J. D., Feola, D. J., Caldwell, G. G., & Thornton, A. (2010) · Journal of the International Association of Physicians in AIDS Care · doi:10.1177/1545109710368721 · Cited by 18 · see citing works
Who should receive the shingles vaccine?
Singh, A., & Englund, K. (2009) · Cleveland Clinic Journal of Medicine · doi:10.3949/ccjm.75a.08046 · Cited by 16 · see citing works
Nailing down the shingles in IBD
Kotton, C. N. (2007) · Inflammatory Bowel Diseases · doi:10.1002/ibd.20161 · Cited by 16 · see citing works
Human Leukocyte Antigens Influence the Antibody Response to Hepatitis B Vaccine.
Jafarzadeh, A., Bagheri-Jamebozorgi, M., Nemati, M., Golsaz‐Shirazi, F., & Shokri, F. (2015) · PubMed · Cited by 15 · see citing works
T cell responses to hepatitis B surface antigen are detectable in non-vaccinated individuals
Weihrauch, M. R., von Bergwelt‐Baildon, M., Kandic, M., Weskott, M., Klamp, W., Rösler, J., & Schultze, J. L. (2008) · World Journal of Gastroenterology · doi:10.3748/wjg.14.2529 · Cited by 13 · see citing works
Fallahi, G., Aghamohammadi, A., Khodadad, A., Hashemi, M., Mohammadinejad, P., Asgarian‐Omran, H., Najafi, M., Farhmand, F., Motamed, F., Soleimani, K., et al. (2014) · Gut and Liver · doi:10.5009/gnl.2014.8.1.24 · Cited by 13 · see citing works
Suzuki, T., Yamauchi, K., Kuwata, T., & Hayashi, N. (2001) · Journal of Gastroenterology and Hepatology · doi:10.1046/j.1440-1746.2001.02530.x · Cited by 13 · see citing works
Li, J., Tan, D., Liu, H., & Li, K. (2011) · PubMed · doi:10.3969/j.issn.1672-7347.2011.11.003 · Cited by 13 · see citing works
Bálint, A., Farkas, K., Kunstár, É. P., Terhes, G., Urbán, E. Z., Szűcs, M., Nyári, T., Bata‐Csörgõ, Z., Nagy, F. T., Szepes, Z., et al. (2014) · Scandinavian Journal of Gastroenterology · doi:10.3109/00365521.2014.928902 · Cited by 9 · see citing works
Nowak, Z., & Karowicz-Bilińska, A. (2007) · PubMed · Cited by 3 · see citing works
Nielsen, T. (2001) · Scandinavian Journal of Gastroenterology · doi:10.1080/00365520118314 · Cited by 1 · see citing works
(2015) · Journal of Crohn s and Colitis · doi:10.1093/ecco-jcc/jju027.557 · Cited by 1 · see citing works
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ACG clinical guideline: Preventive care in inflammatory bowel disease
Farraye, F. A., Melmed, G. Y., Lichtenstein, G. R., & Kane, S. V. (2017) · American Journal of Gastroenterology · doi:10.1038/ajg.2016.537 · Cited by 473 · see citing works
Viral Infections, the Microbiome, and Probiotics
Harper, A., Vijayakumar, V., Ouwehand, A. C., ter Haar, J., Obis, D., Espadaler, J., Binda, S., Desiraju, S., & Day, R. (2021) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2020.596166 · Cited by 177 · see citing works
Pratt, P. K., Nunes, D., Weber, H. C., Little, F. F., Kourkoumpetis, T. K., Patts, G. J., Weinberg, J., & Farraye, F. A. (2018) · Inflammatory Bowel Diseases · doi:10.1093/ibd/izx001 · Cited by 84 · see citing works
Hepatitis B vaccine nonresponders
Saco, T. V., Strauss, A. T., & Ledford, D. K. (2018) · Annals of Allergy Asthma & Immunology · doi:10.1016/j.anai.2018.03.017 · Cited by 77 · see citing works
Vaccination in Patients with Inflammatory Bowel Diseases
Manser, C. N., Maillard, M. H., Rogler, G., Schreiner, P., Rieder, F., Bühler, S., & on behalf of Swiss IBDnet, A. O. W. G. O. T. S. S. O. G. (2020) · Digestion · doi:10.1159/000503253 · Cited by 49 · see citing works
High Immunogenicity to Influenza Vaccination in Crohn’s Disease Patients Treated with Ustekinumab
Doornekamp, L., Goetgebuer, R., Schmitz, K. S., Goeijenbier, M., van der Woude, C. J., Fouchier, R. A. M., Gorp, E. C. M. V., & de Vries, A. C. (2020) · Vaccines · doi:10.3390/vaccines8030455 · Cited by 46 · see citing works
ACG Clinical Guideline Update: Preventive Care in Inflammatory Bowel Disease
Farraye, F. A., Melmed, G., Lichtenstein, G. R., Barnes, E. L., Limketkai, B. N., Caldera, F., & Kane, S. V. (2025) · The American Journal of Gastroenterology · doi:10.14309/ajg.0000000000003541 · Cited by 44 · see citing works
Jones, J., Tse, F., Carroll, M. W., deBruyn, J. C. C., McNeil, S., Pham‐Huy, A., Seow, C. H., Barrett, L. L., Bessissow, T., Carman, N., et al. (2021) · Gastroenterology · doi:10.1053/j.gastro.2021.04.034 · Cited by 39 · see citing works
Benchimol, E. I., Tse, F., Carroll, M. W., deBruyn, J. C. C., McNeil, S., Pham‐Huy, A., Seow, C. H., Barrett, L. L., Bessissow, T., Carman, N., et al. (2021) · Gastroenterology · doi:10.1053/j.gastro.2020.12.079 · Cited by 31 · see citing works
SARS-CoV-2 Vaccination in IBD: Past Lessons, Current Evidence, and Future Challenges
Wellens, J., Colombel, J., Satsangi, J. J., & Wong, S.-Y. (2021) · Journal of Crohn s and Colitis · doi:10.1093/ecco-jcc/jjab046 · Cited by 30 · see citing works
García-Serrano, C., Mirada, G., Marsal, J. R., Ortega, M., Sol, J., Solano, R., Artigues-Barberà, E., & Estany, P. (2020) · BMC Public Health · doi:10.1186/s12889-020-08850-y · Cited by 28 · see citing works
Pittet, L. F., Verolet, C. M., Michetti, P., Girardin, M., Juillerat, P., Mottet, C., Maillard, M. H., Siegrist, C., Posfay-Barbe, K. M., & the Swiss Inflammatory Bowel Disease Cohort Study Group (2019) · The American Journal of Gastroenterology · doi:10.14309/ajg.0000000000000289 · Cited by 28 · see citing works
Management Approaches to Hepatitis B Virus Vaccination Nonresponse.
Yanny, B., Konyn, P., Najarian, L. M., Mitry, A., & Saab, S. (2019) · Europe PMC (PubMed Central) · Cited by 24 · see citing works
Ferreiro‐Iglesias, R., Piqueras, M., Ricart, E., Sempere, L., Roca, M., de Carpi, J. M., Benítez, O., Zabana, Y., Mañosa, M., Rodríguez‐Moranta, F., et al. (2022) · Gastroenterología y Hepatología · doi:10.1016/j.gastrohep.2022.03.012 · Cited by 23 · see citing works
Cagol, L., Seitel, T., Ehrenberg, S., Frivolt, K., Krahl, A., Lainka, E., Gerner, P., Lenhartz, H., Vermehren, J., Radke, M. H., et al. (2019) · Vaccine · doi:10.1016/j.vaccine.2019.12.024 · Cited by 21 · see citing works
Vaccination strategies in pediatric inflammatory bowel disease
Dipasquale, V., & Romano, C. (2017) · Vaccine · doi:10.1016/j.vaccine.2017.09.031 · Cited by 21 · see citing works
Chaparro, M., Gordillo, J., Domènech, E., Esteve, M., Acosta, M. B., Villòria, A., Iglesias-Flores, E. M., Blasi, M., Naves, J. E., Benítez, O., et al. (2020) · The American Journal of Gastroenterology · doi:10.14309/ajg.0000000000000926 · Cited by 20 · see citing works
Self-citationMüller, K. E., Dohos, D., Sipos, Z., Kiss, S., Dembrovszky, F., Kovács, N., Solymár, M., Erőss, B. M., Hegyi, P. J., & Sarlós, P. (2022) · Vaccine · doi:10.1016/j.vaccine.2022.02.027 · Cited by 19 · see citing works
Health Maintenance in Inflammatory Bowel Disease
Mir, F., & Kane, S. V. (2018) · Current Gastroenterology Reports · doi:10.1007/s11894-018-0621-1 · Cited by 19 · see citing works
Jones, J., Tse, F., Carroll, M. W., deBruyn, J. C. C., McNeil, S., Pham‐Huy, A., Seow, C. H., Barrett, L. L., Bessissow, T., Carman, N., et al. (2021) · Journal of the Canadian Association of Gastroenterology · doi:10.1093/jcag/gwab016 · Cited by 19 · see citing works
Vinsard, D. G., Wakefield, D. B., Vaziri, H., & Karagozian, R. (2019) · Inflammatory Bowel Diseases · doi:10.1093/ibd/izz093 · Cited by 18 · see citing works
Seitel, T., Cagol, L., Prelog, M., Frivolt, K., Krahl, A., Trenkel, S., Speth, F., Mayer, B., Almanzar, G., Koletzko, S., et al. (2020) · Vaccine · doi:10.1016/j.vaccine.2020.10.028 · Cited by 17 · see citing works
Effectiveness of Hepatitis B Vaccination for Patients With Inflammatory Bowel and Celiac Disease
Ulrich, J. A., Habash, N. W., Ismail, Y., Tremaine, W. J., Weaver, A. L., Murray, J. A., Loftus, E. V., & Absah, I. (2023) · Clinical Gastroenterology and Hepatology · doi:10.1016/j.cgh.2023.03.025 · Cited by 16 · see citing works
Improving immunization strategies in patients with inflammatory bowel disease
Farshidpour, M. (2019) · Annals of Gastroenterology · doi:10.20524/aog.2019.0351 · Cited by 16 · see citing works
Benchimol, E. I., Tse, F., Carroll, M. W., deBruyn, J. C. C., McNeil, S., Pham‐Huy, A., Seow, C. H., Barrett, L. L., Bessissow, T., Carman, N., et al. (2021) · Journal of the Canadian Association of Gastroenterology · doi:10.1093/jcag/gwab015 · Cited by 15 · see citing works
Infecciones en la enfermedad inflamatoria intestinal
de Santiago, E. R., Albillos, A., & López–Sanromán, A. (2017) · Medicina Clínica · doi:10.1016/j.medcli.2016.12.041 · Cited by 12 · see citing works
Calvet, X., Carpio, D., Rodríguez–Lago, I., García‐Vicuña, R., Acosta, M. B., Juanola, X., Aguas, M., Castillo, C., & Jordi Gratacós, A. (2021) · Gastroenterología y Hepatología · doi:10.1016/j.gastrohep.2021.01.007 · Cited by 12 · see citing works
Health Maintenance for Adult Patients with Inflammatory Bowel Disease
Hashash, J. G., Picco, M. F., & Farraye, F. A. (2021) · Current Treatment Options in Gastroenterology · doi:10.1007/s11938-021-00364-9 · Cited by 12 · see citing works
Immunisation status of children and adolescents with a new diagnosis of inflammatory bowel disease
Ford, T. J., Danchin, M. H., McMinn, A., Perrett, K. P., Alex, G., & Crawford, N. W. (2022) · BMC Infectious Diseases · doi:10.1186/s12879-021-06976-x · Cited by 11 · see citing works
Serious and Opportunistic Infections in Elderly Patients With Inflammatory Bowel Disease.
Lin, E., Lin, K., & Katz, S. (2019) · PubMed Central · Cited by 10 · see citing works
Endo, F., Tabata, T., Sadato, D., Kawamura, M., Ando, N., Oboki, K., Ukaji, M., Kobayashi, K., Kobayashi, Y., Ikeda, T., et al. (2017) · PLoS ONE · doi:10.1371/journal.pone.0171314 · Cited by 7 · see citing works
Calvet, X., Carpio, D., Rodríguez–Lago, I., García‐Vicuña, R., Acosta, M. B., Juanola, X., Aguas, M., Castillo, C., & Jordi Gratacós, A. (2021) · Gastroenterología y Hepatología (English Edition) · doi:10.1016/j.gastre.2021.01.003 · Cited by 6 · see citing works
Ruan, W. H., Nguyen, H., Wyatt, A., Ihekweazu, F. D., Vartabedian, B. S., Karam, L. B., Walsh, S., & Kellermayer, R. (2021) · Journal of Pediatric Gastroenterology and Nutrition · doi:10.1097/mpg.0000000000003211 · Cited by 6 · see citing works
Impact of an Intervention to Promote the Vaccination of Patients with Inflammatory Bowel Disease
García-Serrano, C., Artigues-Barberà, E., Mirada, G., Estany, P., Sol, J., & Ortega, M. (2023) · Vaccines · doi:10.3390/vaccines11111649 · Cited by 6 · see citing works
Vaccination strategies for Korean patients with inflammatory bowel disease
Lee, Y. J., & Kim, E. S. (2022) · The Korean Journal of Internal Medicine · doi:10.3904/kjim.2022.149 · Cited by 6 · see citing works
Vaccines – beliefs and concerns: the voice of patients with inflammatory immunomediated diseases
Abreu, C., Martins, A., Branco, E. A., Rocha, R., Sarmento, A., & Magro, F. (2023) · European Journal of Gastroenterology & Hepatology · doi:10.1097/meg.0000000000002589 · Cited by 4 · see citing works
Common Mistakes in Managing Patients with Inflammatory Bowel Disease
Gisbert, J. P., & Chaparro, M. (2024) · Journal of Clinical Medicine · doi:10.3390/jcm13164795 · Cited by 4 · see citing works
Infections in inflammatory bowel disease
de Santiago, E. R., Albillos, A., & López–Sanromán, A. (2017) · Medicina Clínica (English Edition) · doi:10.1016/j.medcle.2017.04.020 · Cited by 4 · see citing works
Gheonea, T. C., Bogdán, M., Meca, A.-D., Rogoveanu, I., & Oancea, C. N. (2024) · Frontiers in Pharmacology · doi:10.3389/fphar.2024.1380878 · Cited by 3 · see citing works
Ostrov, B. E., & Amsterdam, D. (2021) · Immunological Investigations · doi:10.1080/08820139.2021.1900863 · Cited by 3 · see citing works
Silva, V. M., Capela, T. L., Freitas, M., Gonçalves, T. C., Carvalho, P. B., de Castro, F. D., Moreira, M. J., & Cotter, J. B. (2022) · Inflammatory Bowel Diseases · doi:10.1093/ibd/izac187 · Cited by 3 · see citing works
Makarova, E., Goleva, O. V., Gabrusskaya, T., Ulanova, N., Volkova, N., Shilova, E. R., Tolkmit, M., Revnova, M. O., Михайловна, Х. С., & Kostik, M. M. (2025) · World Journal of Clinical Pediatrics · doi:10.5409/wjcp.v14.i3.104704 · Cited by 2 · see citing works
Health Care Maintenance in Patients with Crohn's Disease
Hashash, J. G., & Farraye, F. A. (2022) · Gastroenterology Clinics of North America · doi:10.1016/j.gtc.2021.12.015 · Cited by 2 · see citing works
Ferreiro‐Iglesias, R., Piqueras, M., Ricart, E., Sempere, L., Roca, M., de Carpi, J. M., Benítez, O., Zabana, Y., Mañosa, M., Rodríguez‐Moranta, F., et al. (2022) · Gastroenterología y Hepatología (English Edition) · doi:10.1016/j.gastre.2022.03.004 · Cited by 2 · see citing works
Hard Palate Lesion due to Herpes Zoster Virus Infection
Gomibuchi, T., & Tsutsumi, T. (2016) · Internal Medicine · doi:10.2169/internalmedicine.55.7064 · Cited by 1 · see citing works
Infection risk of targeted synthetic drugs used in immune-mediated inflammatory diseases
García, P., Velasco, A. A., & Miguel, M. D. (2022) · Boletín de información farmacoterapéutica de Navarra · doi:10.54095/bitn20223002en · Cited by 1 · see citing works
Response to COVID-19 Vaccination in Patients with Inflammatory Bowel Disease on Biological Treatment
Bodini, G., Giuliana, E., Giberti, I., Guarona, G., Benvenuto, F., Ferretti, E., Demarzo, M. G., Rin, G. D., Icardi, G., & Giannini, E. G. (2022) · Gastrointestinal Disorders · doi:10.3390/gidisord4020009 · Cited by 1 · see citing works
Beaudoux, O., Cadiot, G., & Bressenot, A. (2020) · Annales de Pathologie · doi:10.1016/j.annpat.2019.12.007
Healthcare Maintenance in the Patient with Inflammatory Bowel Disease: High-Yield Interventions
Roitman, I., Mone, A., & Swaminath, A. C. (2021) · Clinical gastroenterology · doi:10.1007/978-3-030-81780-0_7
Mishra, V. (2021) · University journal of medicine and medical specialities
Vaccination for Inflammatory Bowel Disease Patients
Yunihastuti, E. (2022) · The Indonesian Journal of Gastroenterology Hepatology and Digestive Endoscopy · doi:10.24871/231202252-61
Montori, M., Martini, F., BLASIO, F. D., Buono, T., Quatraccioni, C., Guardati, P., CALZOLARI, M., ROSSI, C., Bendia, E., Menzo, S., et al. (2022) · Minerva Gastroenterology · doi:10.23736/s2724-5985.22.03134-5
Tomanguillo, J., Searls, L., Annie, F., Kemper, S. E., & Naravadi, V. V. R. (2023) · Cureus · doi:10.7759/cureus.34004
Roblin, X., Vieujean, S., Nancey, S., Hébuterne, X., Arab-Hocine, N., Savoye, G., Viennot, S., Bouguen, G., Fuméry, M., Duru, G., et al. (2025) · Journal of Crohn s and Colitis · doi:10.1093/ecco-jcc/jjaf115
García-Serrano, C., Mirada, G., Marsal, J. R., Ortega, M., Sol, J., Solano, R., Artigues, E. M., & Estany, P. (2020) · Figshare · doi:10.6084/m9.figshare.12332330
Soleto, I., Marín, A. C., Martin, M. B., Bernardo, D., Chaparro, M., & Gisbert, J. P. (2026) · International Journal of Molecular Sciences · doi:10.3390/ijms27010531
Self-citation
- Authors
- Marín, A. C.
- Affiliations
- Hospital Universitario de La Princesa (ES)
- Corresponding author
- Marín, Alicia C
- ORCID
- Marín, Alicia C
- Venue
- World Journal of Gastroenterology
- Publisher
- Baishideng Publishing Group Inc.
- Published
- 2015
- Volume
- 21
- Issue
- 40
- Pages
- 11273
- ISSN
- 1007-9327 (ISSN-L)
- PMC
- PMC4616204
- OpenAlex
- W2337226296
- Cited by
- 58
- References
- 78
- Citations by year
- 2026: 1 · 2025: 3 · 2024: 3 · 2023: 4 · 2022: 11 · 2021: 13 · 2020: 7 · 2019: 6 · 2018: 4 · 2017: 5 · 2016: 1
- FWCI
- 0.42
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- cc-by-nc
- Locations
- World Journal of Gastroenterology (publishedVersion, cc-by-nc)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas) (submittedVersion, other-oa)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Inflammatory Bowel Disease
- Life Sciences › Immunology and Microbiology › Immunology › Immune responses and vaccinations
- Health Sciences › Medicine › Rheumatology › Rheumatoid Arthritis Research and Therapies
- Keywords
- inflammatory bowel disease, vaccine immunogenicity, immunosuppressive therapy, hepatitis B vaccine, pneumococcal vaccine, influenza vaccination, papillomavirus vaccine, tetanus vaccine, MMR vaccine, varicella vaccine, herpes zoster vaccine, seroprotection, infection control, immune-mediated diseases
- MeSH terms
- Antibodies, Colitis, Ulcerative, Crohn Disease, Humans, Immunization Schedule, Immunosuppressive Agents, Serologic Tests, Vaccination, Vaccines, Attenuated, Vaccines, Inactivated, Biomarkers, Immunocompromised Host
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