The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Systemic immune-inflammation index for predicting prognosis of colorectal cancer
Open accessAbstract
AIM: To investigate the clinical significance of preoperative systemic immune-inflammation index (SII) in patients with colorectal cancer (CRC). METHODS: A retrospective analysis of 1383 cases with CRC was performed following radical surgery. SII was calculated with the formula SII = (P × N)/L, where P, N, and L refer to peripheral platelet, neutrophil, and lymphocyte counts, respectively. The clinicopathological features and follow-up data were evaluated to compare SII with other systemic inflammation-based prognostic indices such as the neutrophil-lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR) in patients with CRC. RESULTS: < 0.05). The SII was an independent predictor of OS and DFS in multivariate analysis. The area under the receiver-operating characteristics (ROC) curve for SII (0.707) was larger than those for NLR (0.602) and PLR (0.566). In contrast to NLR and PLR, SII could effectively discriminate between the TNM subgroups. CONCLUSION: SII is a more powerful tool for predicting survival outcome in patients with CRC. It might assist the identification of high-risk patients among patients with the same TNM stage.
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Hu, B., Yang, X.-R., Xu, Y., Sun, Y.-F., Sun, C., Guo, W., Zhang, X., Wang, W.-M., Qiu, S.-J., Zhou, J., et al. (2014) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-14-0442 · Cited by 2,493
Cancer-related inflammation and treatment effectiveness
Diakos, C. I., Charles, K. A., McMillan, D. C., & Clarke, S. J. (2014) · The Lancet Oncology · doi:10.1016/s1470-2045(14)70263-3 · Cited by 2,193
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Inflammation-Related Biomarkers for the Prediction of Prognosis in Colorectal Cancer Patients
Yamamoto, T., Kawada, K., & Obama, K. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22158002 · Cited by 445
Prognostic value of Systemic immune-inflammation index in cancer: A meta-analysis
Yang, R., Chang, Q., Meng, X., Gao, N., & Wang, W. (2018) · Journal of Cancer · doi:10.7150/jca.25691 · Cited by 441
Liu, J., Li, S., Zhang, S., Liu, Y., Ma, L., Zhu, J., Xin, Y., Wang, Y., Yang, C., & Cheng, Y. (2019) · Journal of Clinical Laboratory Analysis · doi:10.1002/jcla.22964 · Cited by 364
Jin, Z., Wu, Q., Chen, S., Gao, J., Li, X., Zhang, X., Zhou, Y., He, D., Cheng, Z., Zhu, Y., et al. (2021) · Journal of Inflammation Research · doi:10.2147/jir.s283835 · Cited by 312
Association between Systemic Immune-Inflammation Index and Diabetic Depression
Wang, J., Zhou, D., Dai, Z., & Li, X. (2021) · Clinical Interventions in Aging · doi:10.2147/cia.s285000 · Cited by 238
Metadata
- Authors
- Chen, J.-H., Zhai, E.-T., Yuan, Y.-J., Wu, K.-M., Xu, J.-B., Peng, J.-J., Chen, C.-Q., He, Y.-L., & Cai, S.-R.
- Venue
- World Journal of Gastroenterology
- Publisher
- Baishideng Publishing Group Inc.
- Published
- 2017
- Volume
- 23
- Issue
- 34
- Pages
- 6261
- ISSN
- 1007-9327 (ISSN-L)
- OpenAlex
- W2754430781
- Cited by
- 723
- References
- 2
- FWCI
- 6.89
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Chen, J.-H., Zhai, E.-T., Yuan, Y.-J., Wu, K.-M., Xu, J.-B., Peng, J.-J., Chen, C.-Q., He, Y.-L., & Cai, S.-R. (2017). Systemic immune-inflammation index for predicting prognosis of colorectal cancer. World Journal of Gastroenterology. https://doi.org/10.3748/wjg.v23.i34.6261
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