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Cited by 445

The DOI matches its Crossref record; 73 of the 73 references it cites were found in a registry or an index.

Inflammation-Related Biomarkers for the Prediction of Prognosis in Colorectal Cancer Patients

Open access
Yamamoto, Takehito, Kawada, Kenji, Obama, Kazutaka·2021·International Journal of Molecular Sciences

Abstract

Colorectal cancer (CRC) is the leading cause of cancer deaths around the world. It is necessary to identify patients with poor prognosis or with high risk for recurrence so that we can selectively perform intensive treatments such as preoperative and/or postoperative chemotherapy and extended surgery. The clinical usefulness of inflammation-related prognostic biomarkers available from routine blood examination has been reported in many types of cancer, e.g., neutrophil–lymphocyte ratio (NLR), lymphocyte–C-reactive protein ratio (LCR), platelet–lymphocyte ratio (PLR), lymphocyte–monocyte ratio (LMR), and so on. Moreover, some scoring systems based on circulating blood cell counts and albumin concentration have been also reported to predict cancer patients’ prognosis, such as the Glasgow prognostic score (GPS), systemic inflammation score (SIS), and prognostic nutritional index (PNI). The optimal biomarker and optimal cutoff value of the markers can be different depending on the cancer type. In this review, we summarize the prognostic impact of each inflammation-related marker in CRC.

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Metadata

Authors
Yamamoto, T., Kawada, K., & Obama, K.
Venue
International Journal of Molecular Sciences
Publisher
MDPI AG
Published
2021-07-27
Volume
22
Issue
15
Pages
8002
ISSN
1422-0067 (ISSN-L)
OpenAlex
W3183775578
Cited by
445
References
73
FWCI
20.71
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: Inflammation-Related Biomarkers for the Prediction of Prognosis in Colorectal Cancer Patients. https://app.cochat.ai/papers/10.3390/ijms22158002
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Yamamoto, T., Kawada, K., & Obama, K. (2021). Inflammation-Related Biomarkers for the Prediction of Prognosis in Colorectal Cancer Patients. International Journal of Molecular Sciences. https://doi.org/10.3390/ijms22158002

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