Amygdala and hippocampal activity during acquisition and extinction of human fear conditioning

Knight, David C., Smith, Christine N., Cheng, Dominic T., Stein, Elliot A., Helmstetter, Fred J.·2004·Cognitive, Affective, & Behavioral Neuroscience

DOI 10.3758/cabn.4.3.317

Cited by (249)

Items 101–200 of 249

The amygdala, top-down effects, and selective attention to features.
Richard H. A. H. Jacobs, R. Renken, A. Aleman, F. Cornelissen · 2012 · Neuroscience and Biobehavioral Reviews
Impaired fear extinction in adolescent rodents: Behavioural and neural analyses
Kathryn Baker, Madelyne A. Bisby, Rick Richardson · 2016 · Neuroscience & Biobehavioral Reviews
Function and mechanisms of memory destabilization and reconsolidation after retrieval
Satoshi Kida · 2020 · Proceedings of the Japan Academy Series B
Cerebellar vermis contributes to the extinction of conditioned fear
A. Utz, Mario Thürling, Thomas Ernst, Andrea Hermann, Rudolf M. Stark, Oliver Tobias Wolf, Dagmar Timmann, Christian Josef Merz · 2015 · Neuroscience Letters
Cortisol disrupts the neural correlates of extinction recall
Valerie L. Jentsch, Christian Josef Merz, Silke Lissek, Oliver Tobias Wolf · 2016 · NeuroImage
Recent Advances in the Understanding and Treatment of Anxiety Disorders
Steven L. Shearer · 2007 · Primary Care Clinics in Office Practice
Fear of pain in children and adolescents with neuropathic pain and complex regional pain syndrome
Laura E. Simons · 2015 · Pain
Forging Neuroimaging Targets for Recovery in Opioid Use Disorder
Jennifer Lorraine Stewart, April Chelsea May, Robin L. Aupperle, Jerzy Bodurka · 2019 · Frontiers in Psychiatry
Trust‐Based Relational Intervention™: Interactive Principles for Adopted Children With Special Social‐Emotional Needs
Karyn B. Purvis, David Cross, Jacquelyn S. Pennings · 2009 · The Journal of Humanistic Counseling Education and Development
Neural correlates of aversive conditioning: development of a functional imaging paradigm for the investigation of anxiety disorders
Isabelle Reinhardt, Andreas Jansen, Thilo Kellermann, André Schüppen, Nils Kohn, Alexander L. Gerlach, Tilo T. J. Kircher · 2010 · European Archives of Psychiatry and Clinical Neuroscience
Dynamic neural activity recorded from human amygdala during fear conditioning using magnetoencephalography
Sandra N. Moses, Jon M. Houck, Tim Martin, Faith M. Hanlon, Jennifer D. Ryan, Robert J. Thoma, Michael P. Weisend, Eric M. Jackson, Eero Pekkonen, Claudia D. Tesche · 2006 · Brain Research Bulletin
Exposure therapy, D-cycloserine, and functional magnetic resonance imaging in patients with snake phobia: a randomized pilot study.
Andrea M. Nave, D. Tolin, M. Stevens · 2012 · Journal of Clinical Psychiatry
Effects of Neonatal Amygdala Lesions on Fear Learning, Conditioned Inhibition, and Extinction in Adult Macaques
Andy M. Kazama, E. Heuer, M. Davis, J. Bachevalier · 2012 · Behavioral Neuroscience
Cortisol enhances neural differentiation during fear acquisition and extinction in contingency aware young women
Katharina Tabbert, Christian Josef Merz, Tim Klucken, Jan Schweckendiek, Dieter Vaitl, Oliver Tobias Wolf, Rudolf M. Stark · 2010 · Neurobiology of Learning and Memory
Daily physical complaints and hippocampal function: An fMRI study of pain modulation by anxiety
Motoharu Gondo, Yoshiya Moriguchi, Naoki Kodama, Noriko Sato, Nobuyuki Sudo, Chiharu Kubo, Gen Komaki · 2012 · NeuroImage
The Threatened Brain
Stephen Maren · 2007 · Science
Psychopaths Show Enhanced Amygdala Activation during Fear Conditioning
Douglas H. Schultz, Nicholas L. Balderston, Arielle Ryan Baskin-sommers, Christine L. Larson, Fred J. Helmstetter · 2016 · Frontiers in Psychology
EEG-based Computer Control Interface for Brain-Machine Interaction
József Katona, Attila Kővári · 2015 · International Journal of Online and Biomedical Engineering (iJOE)
Dispositional cognitive reappraisal modulates the neural correlates of fear acquisition and extinction
Andrea Hermann, Tanja Keck, Rudolf M. Stark · 2014 · Neurobiology of Learning and Memory
Amygdala Adaptation and Temporal Dynamics of the Salience Network in Conditioned Fear: A Single-Trial fMRI Study
Siyang Yin, Yuelu Liu, Nathan M. Petro, Andreas Keil, M. Ding · 2018 · eNeuro
Pavlovian conditioned diminution of the neurobehavioral response to threat
Adam M. Goodman, Nathaniel G. Harnett, David C. Knight · 2017 · Neuroscience & Biobehavioral Reviews
Painful stimuli evoke potentials recorded from the medial temporal lobe in humans
C.C. Liu, Shinji Ohara, Piotr J. Franaszczuk, N. Zagzoog, Michela Gallagher, Fred A. Lenz · 2009 · Neuroscience
Hippocampal Erk mechanisms linking prediction error to fear extinction: Roles of shock expectancy and contextual aversive valence
Kyu Hwan Huh, Yomayra F. Guzmán, Natalie Celia Tronson, Anita L. Guedea, Can Gao, Jelena Radulović · 2009 · Learning & Memory
Extinction resistant changes in the human auditory association cortex following threat learning
Annemieke M. Apergis-Schoute, Daniela Schiller, Joseph E. LeDoux, Elizabeth A. Phelps · 2014 · Neurobiology of Learning and Memory
ApoE isoform‐dependent deficits in extinction of contextual fear conditioning
Reid H. J. Olsen, Maayan R. Agam, Michael John Davis, Jacob Raber · 2012 · Genes Brain & Behavior
Implementing Trust-Based Relational Intervention® in a Charter School at a Residential Facility for At-Risk Youth
Sheri R. Parris, Moe Dozier, Karyn B. Purvis, Charlsie Whitney, Amy Grisham, David Cross · 2014 · Contemporary School Psychology
Fear extinction in humans: Effects of acquisition–extinction delay and masked stimulus presentations
Armita Golkar, Arne Öhman · 2012 · Biological Psychology
Reframing the Past: Role of Memory Processes in Emotion Regulation
Rosalie Samide, Maureen Ritchey · 2020 · Cognitive Therapy and Research
White matter microstructure varies with post-traumatic stress severity following medical trauma
Nathaniel G. Harnett, Edward W. Ference, Amy J. Knight, David C. Knight · 2018 · Brain Imaging and Behavior
A mechanism-oriented approach to psychopathology: The role of Pavlovian conditioning
Frauke Nees, Angela Heinrich, Herta Flor · 2015 · International Journal of Psychophysiology
28Silicon Irradiation Impairs Contextual Fear Memory in B6D2F1 Mice
Jacob Raber, Tessa Marzulla, Blair Stewart, Amy Kronenberg, Mitchell S. Turker · 2015 · Radiation Research
Altered amygdala function in nicotine addiction: insights from human neuroimaging studies.
Y. Mihov, R. Hurlemann · 2012 · Neuropsychologia
Psychophysiological Investigation of Combat Veterans with Subthreshold Post-traumatic Stress Disorder Symptoms
Michelle E. Costanzo, Tanja Jovanović, Seth Davin Norrholm, Rochelle Ndiongue, Brian J. Reinhardt, Michael J. Roy · 2016 · Military Medicine
Rapid Amygdala Responses during Trace Fear Conditioning without Awareness
Nicholas L. Balderston, Douglas H. Schultz, Sylvain Baillet, Fred J. Helmstetter · 2014 · PLoS ONE
Human trace fear conditioning: right-lateralized cortical activity supports trace-interval processes
Abhishek Haritha, Kimberly H. Wood, Lawrence Ver Hoef, David C. Knight · 2012 · Cognitive Affective & Behavioral Neuroscience
Altered resting-state brain activity at functional MRI during automatic memory consolidation of fear conditioning
Tingyong Feng, Pan Feng, Zhencai Chen · 2013 · Brain Research
Fear conditioning is associated with dynamic directed functional interactions between and within the human amygdala, hippocampus, and frontal lobe
C.C. Liu, Nathan E. Crone, Piotr J. Franaszczuk, Dominic T. Cheng, David J. Schretlen, Fred A. Lenz · 2011 · Neuroscience
The Effect of Threat on Novelty Evoked Amygdala Responses
Nicholas L. Balderston, Douglas H. Schultz, Fred J. Helmstetter · 2013 · PLoS ONE
Delay and trace fear conditioning in a complex virtual learning environment—neural substrates of extinction
Heike Ewald, Evelyn Glotzbach-Schoon, Antje B. M. Gerdes, Marta Andreatta, Mathias MÃ ⁄ ller, Andreas Mühlberger, Paul Pauli · 2014 · Frontiers in Human Neuroscience
The Missing Link in Early Emotional Processing
L. Carretié, R. K. Yadav, C. Méndez-Bértolo · 2020 · Emotion Review
Facilitating translational science in anxiety disorders by adjusting extinction training in the laboratory to exposure-based therapy procedures
Maike Hollandt, Adrian Wroblewski, Yunbo Yang, Isabelle C. Ridderbusch, Tilo T. J. Kircher, Alfons O. Hamm, Benjamin Straube, Jan Richter · 2020 · Translational Psychiatry
Brain reward circuitry: The overlapping neurobiology of trauma and substance use disorders
Timothy I. Michaels, Emily Stone, Sonali Singal, Vladan Novakovic, Robert L. Barkin, Stacy J. Barkin · 2021 · World Journal of Psychiatry
Effects of RU486 in Treatment of Traumatic Stress-Induced Glucocorticoid Dysregulation and Fear-Related Abnormalities: Early versus Late Intervention
Chen-Cheng Lin, Pao‐Yun Cheng, Michael Hsiao, Yia‐Ping Liu · 2022 · International Journal of Molecular Sciences
Classical conditioning in borderline personality disorder: an fMRI study
Krause-Utz, Annegret, Keibel-Mauchnik, Jana, Ebner-Priemer, Ulrich, Bohus, Martin, Schmahl, Christian · 2016 · European Archives of Psychiatry and Clinical Neuroscience
Pair exposure with conspecific during fear conditioning induces the link between freezing and passive avoidance behaviors in rats
Hyunchan Lee, Jihyun Noh · 2016 · Neuroscience Research
Enhanced Discriminative Fear Learning of Phobia-Irrelevant Stimuli in Spider-Fearful Individuals
Carina Mosig, Christian Josef Merz, Cornelia Mohr, Dirk Adolph, Oliver Tobias Wolf, Silvia Schneider, Jürgen Margraf, Armin Zlomuzica · 2014 · Frontiers in Behavioral Neuroscience
The case for hemispheric lateralization of the human amygdala in fear processing
Tao Xie, Sanne J.H. van Rooij, Cory S. Inman, Shuo Wang, Peter Brunner, Jon Timothy Willie · 2025 · Molecular Psychiatry
Painful laser stimuli induce directed functional interactions within and between the human amygdala and hippocampus
C.C. Liu, Christine Shi, Piotr J. Franaszczuk, Nathan E. Crone, David J. Schretlen, Shinji Ohara, Fred A. Lenz · 2011 · Neuroscience
Medial Prefrontal Cortex Activity during the Extinction of Conditioned Fear: An Investigation Using Functional Near-Infrared Spectroscopy
Anne Guhn, Thomas Dresler, Tim Hahn, Andreas Mühlberger, Andreas Ströhle, Jürgen Deckert, Martin J. Herrmann · 2012 · Neuropsychobiology
Oestradiol, threat conditioning and extinction, post‐traumatic stress disorder, and prolonged exposure therapy: A common link
Mira Z. Hammoud, Edna B. Foa, Mohammed R. Milad · 2019 · Journal of Neuroendocrinology
Optimizing treatments for anxiety by age and genetics
B.J. Casey, Francis S. Lee · 2015 · Annals of the New York Academy of Sciences
Limbic areas are functionally decoupled and visual cortex takes a more central role during fear conditioning in humans
Chrysa D. Lithari, Stephan Moratti, Nathan Weisz · 2016 · Scientific Reports
Fear Extinction Learning in Posttraumatic Stress Disorder
Yana Lokshina, Jony Sheynin, Gregory S. Vogt, Israel Liberzon · 2023 · Current topics in behavioral neurosciences
Risk for anxiety and implications for treatment: developmental, environmental, and genetic factors governing fear regulation
Catherine A. Hartley, Betty Jo Casey · 2013 · Annals of the New York Academy of Sciences
Neural Substrates Underlying Learning-Related Changes of the Unconditioned Fear Response
Kimberly H. Wood, Dystany Kuykendall, Lawrence Ver Hoef, David C. Knight · 2013 · The Open Neuroimaging Journal
Individual Differences in Anticipatory Somatosensory Cortex Activity for Shock is Positively Related with Trait Anxiety and Multisensory Integration
Steven G. Greening, Tae‐Ho Lee, Mara Mather · 2016 · Brain Sciences
Dissociation of neuronal, electrodermal, and evaluative responses in disgust extinction.
Tim Klucken, Jan Schweckendiek, Christian Josef Merz, Dieter Vaitl, Rudolf M. Stark · 2013 · Behavioral Neuroscience
Specific Phobia: A Disorder of Fear Conditioning and Extinction
Dan Joseph Stein, Hisato Matsunaga · 2006 · CNS Spectrums
Thalamic volume and fear extinction interact to predict acute posttraumatic stress severity
Elizabeth R. Steuber, Antonia V. Seligowski, Alyssa R. Roeckner, Mariam Reda, Lauren A. M. Lebois, Sanne J.H. van Rooij, Vishnu P. Murty, Timothy D. Ely, Steven E. Bruce, Stacey L. House et al. · 2021 · Journal of Psychiatric Research
Classically conditioned fear responses are preserved following unilateral temporal lobectomy in humans when concurrent US-expectancy ratings are used
Evelien Coppens, Adriaan Spruyt, Mathieu Vandenbulcke, Wim Van Paesschen, Debora Vansteenwegen · 2009 · Neuropsychologia
Temporal dynamics of fMRI signal changes during conditioned interoceptive pain-related fear and safety acquisition and extinction
Franziska Labrenz, Tamás Spisák, Thomas Ernst, Carlos Alexandre Gomes, Harald H. Quick, Nikolai Axmacher, Sigrid Elsenbruch, Dagmar Timmann · 2022 · Behavioural Brain Research
Subgenual and Hippocampal Pathways in Amygdala Are Set to Balance Affect and Context Processing
Mary Kate P. Joyce, Jingyi Wang, Helen Barbas · 2023 · Journal of Neuroscience
Empirically supported psychological treatments and the Research Domain Criteria (RDoC)
Dean McKay, David F. Tolin · 2016 · Journal of Affective Disorders
Pharmacological rewriting of fear memories: A beacon for post-traumatic stress disorder
Ankit Uniyal, Raghunath Singh, Ansab Akhtar, Jatinder Dhaliwal, Anurag Kuhad, Sangeeta Pilkhwal Sah · 2019 · European Journal of Pharmacology
Eye movements are captured by a perceptually simple conditioned stimulus in the absence of explicit contingency knowledge.
Lauren S. Hopkins, Fred J. Helmstetter, Deborah E. Hannula · 2016 · Emotion
Comparing three extinction methods to reduce fear expression and generalization
Yu Chen, Xiao Lin, Sizhi Ai, Yan Sun, Le Shi, Shiqiu Meng, Lin Lü, Jie Shi · 2021 · Behavioural Brain Research
Parsing neural circuits of fear learning and extinction across basic and clinical neuroscience: Towards better translation
Ho Namkung, Kerrie L. Thomas, Jérémy Hall, Akira Sawa · 2021 · Neuroscience & Biobehavioral Reviews
Neuroimaging contributions to novel surgical treatments for intractable obsessive-compulsive disorder
Rodman, Alexandra M, Milad, Mohammed R, Deckersbach, Thilo, Im, Jamie, Chou, Tina, Dougherty, Darin D · 2012 · Expert Review of Neurotherapeutics
The Impact of Cognitive, Physical, and Psychological Stressors on Subsequent Cognitive Performance
Kristy Martin, Andrew P. Flood, David B. Pyne, Julien D. Périard, Richard James Keegan, Ben Rattray · 2021 · Human Factors The Journal of the Human Factors and Ergonomics Society
Neural mechanisms of human temporal fear conditioning
Nathaniel G. Harnett, Joshua R. Shumen, Pooja A. Wagle, Kimberly H. Wood, Muriah D. Wheelock, James H. Baños, David C. Knight · 2016 · Neurobiology of Learning and Memory
How Fear Memory is Updated: From Reconsolidation to Extinction?
Jiahui Chen, Zhuowen Fang, Xiaolan Zhang, Yanrong Zheng, Zhong Chen · 2025 · Neuroscience Bulletin
In the face of adversity: Refugee children’s traumatic stressors, trust, and prosocial behavior
Keng‐Hie Song, Ju‐Hyun Song, Tina Malti · 2023 · International Journal of Behavioral Development
Ready for translation: non-invasive auricular vagus nerve stimulation inhibits psychophysiological indices of stimulus-specific fear and facilitates responding to repeated exposure in phobic individuals
Christoph Szeska, Kai Klepzig, Alfons O. Hamm, Mathias Weymar · 2025 · Translational Psychiatry
The effect of partial and continuous reinforcement on the generalization of conditioned fear in humans
Shaochen Zhao, Wei Chen, Jing Jie, Min Fan, Junjiao Li, Muxin Rong, Zifan Yang, Xifu Zheng · 2022 · Learning and Motivation
Human serotonin transporter availability predicts fear conditioning
Fredrik Åhs, Andreas Frick, Tomas Furmark, Mats Fredrikson · 2014 · International Journal of Psychophysiology
Behavioral, Physiological and EEG Activities Associated with Conditioned Fear as Sensors for Fear and Anxiety
Jui‐Hong Chien, Luana Colloca, Anna Korzeniewska, Timothy J. Meeker, O. Joe Bienvenu, Mark Saffer, Fred A. Lenz · 2020 · Sensors
Neurobehavioral Mechanisms of Traumatic Stress in Post-traumatic Stress Disorder
M. Danet Lapiz Bluhm, Alan L. Peterson · 2014 · Current topics in behavioral neurosciences
Dynamic competition between large-scale functional networks differentiates fear conditioning and extinction in humans
Lars Marstaller, Hana Burianová, David C. Reutens · 2016 · NeuroImage
The Effect of Early Life Stress on Emotional Behaviors in GPR37KO Mice
Vandana Veenit, Xiaoqun Zhang, Antonio Ambrosini, Vasco C. Sousa, Per Svenningsson · 2021 · International Journal of Molecular Sciences
Comparison of behavioral and brain indices of fear renewal during a standard vs. novel immersive reality Pavlovian fear extinction paradigm in healthy adults
Nicole L. Zabik, Craig Peters, Allesandra S. Iadipaolo, Hilary A. Marusak, Christine A. Rabinak · 2022 · Behavioural Brain Research
Discrimination Exposure, Neural Reactivity to Stress, and Psychological Distress
Devon K Grey, Juliann B. Purcell, Kristen N. Buford, Mark A. Schuster, Marc N. Elliott, Susan Tortolero Emery, Sylvie Mrug, David C. Knight · 2024 · American Journal of Psychiatry
Sex differences in contextual fear conditioning and extinction after acute and chronic nicotine treatment
Jack V. Keady, Marissa C. Hessing, Judy C. Songrady, Kristen A. McLaurin, Jill R Turner · 2024 · Biology of Sex Differences
The effect of stress and reward on encoding future fear memories
Lauren E. DiFazio, Michael S. Fanselow, Melissa J. Sharpe · 2021 · Behavioural Brain Research
Measuring extinction learning across the lifespan – Adaptation of an optimized paradigm to closely match exposure treatment procedures
Dirk Adolph, Tabea Flasinski, Michael W. Lippert, Verena Pflug, Alfons O. Hamm, Jan Richter, Jürgen Margraf, Silvia Schneider · 2022 · Biological Psychology
Using optimal combined moderators to define heterogeneity in neural responses to randomized conditions: Application to the effect of sleep loss on fear learning
Meredith L. Wallace, Layla Banihashemi, Christopher Paul O'Donnell, Vishwajit Laxmikant Nimgaonkar, Chowdari V. Kodavali, Rebecca Landes McNamee, Anne Germain · 2018 · NeuroImage
Emotional responses in monkeys differ depending on the stimulus type, sex, and neonatal amygdala lesion status.
Alejandra Medina, Jennifer Torres, Andy M. Kazama, Jocelyne Bachevalier, Jessica Raper · 2020 · Behavioral Neuroscience
Fear, Trauma, and Posttraumatic Stress Disorder: Clinical, Neurobiological, and Cultural Perspectives
Mikael Rubin, Maya Neria, Yuval Neria · 2016 · Springer eBooks
Neurocognitive mechanisms of mental imagery-based disgust learning
Jinxia Wang, Siyi Shen, Benjamin Becker, Michelle Hei Lam Tsang, Ying Mei, Jan Wikgren, Yi Lei · 2024 · Behaviour Research and Therapy
A amígdala e a tênue fronteira entre memória e emoção
Fabíola da Silva Albuquerque, Regina H. Silva · 2009 · Revista de Psiquiatria do Rio Grande do Sul
Neuronal Basis of Learning
Joseph E. Steinmetz, Derick H. Lindquist · 2009
Comparing brain activity patterns during spontaneous exploratory and cue-instructed learning using single photon-emission computed tomography (SPECT) imaging of regional cerebral blood flow in freely behaving rats
Anja Mannewitz, Joerg Bock, Silke Kreitz, A. Hess, Jürgen Goldschmidt, Henning Scheich, Katharina Braun · 2018 · Brain Structure and Function
Anticipation and the Neural Response to Threat
Nathaniel G. Harnett, Kimberly H. Wood, Muriah D. Wheelock, Amy J. Knight, David C. Knight · 2016 · Springer eBooks
Altered fronto-limbic-motor response to stress differs between functional and epileptic seizures in a TBI model
Adam M. Goodman, Jane B. Allendorfer, Gabriella C Taylor, Noah S. Philip, Stephen Correia, Andrew S. Blum, William Curt LaFrance Jr, Jerzy P. Szaflarski · 2024 · Epilepsy & Behavior
Fear learning sculpts functional brain connectivity at rest beyond the traditional fear network
Christoph Fraenz, Dorothea Metzen, Christian Josef Merz, Helene Selpien, Patrick Friedrich, Sebastian Ocklenburg, Nikolai Axmacher, Erhan Genç · 2025 · Behavioural Brain Research
Downregulation of lncRNAs Gomafu, NONMMUT033604.2, and NONMMUT064397.2 in the hippocampus of mice with model of post-traumatic stress disorder
Anastasia Klymenko, Vasyl S. Nagibin, Anastasiia Horlova, Yulia Dobropolska, R. Bogovik, Dmytro Stroy, Dmytro S. Isaev, Victor Dosenko · 2024 · The World Journal of Biological Psychiatry
There is nothing to fear but the amygdala: applying advances in the neuropsychiatry of fear to public policy
Lawrence Amsel, Spencer Harbo, Amitai Halberstam · 2014 · Mind & Society
Impairments in trace EB conditioning by knife-cut lesions to the fornix in rabbits: Reversal by galantamine
Barbara B. Oswald, Stephanie A. Maddox, Donald A. Powell · 2007 · Neurobiology of Learning and Memory
The Cognitive Neuroscience of Fear Learning
Daniel Stjepanović, Kevin S. LaBar · 2018 · Wiley eBooks
The human amygdala in threat learning and extinction
Sjoerd W. Meijer, Eleonora Carpino, Benjamin R. Kop, Jesse Lam, Lycia D. de Voogd, Karin Roelofs, Lennart Verhagen · 2026 · Science Advances
Behavioral interventions to eliminate fear responses
Jing-Li Yue, Le Shi, Xiao Lin, Muhammad Zahid Khan, Jie Shi, Lin Lü · 2018 · Science China Life Sciences