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MALAT1: A long non‑coding RNA highly associated with human cancers (Review)

Zhao, Miaomiao, Wang, Songpo, Li, Qi, Ji, Qing, Guo, Piaoting, Liu, Xiaowei·2018·Oncology Letters
DOI 10.3892/ol.2018.8613PMC PMC6006327
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Figure 1. Literature about MALAT1. Articles were searched on PubMed, limited to ‘between 2003 and December 2014’.
Figure 1. Literature about MALAT1. Articles were searched on PubMed, limited to ‘between 2003 and December 2014’.CC BY-NC-ND · PubMed Central
Figure 2. Genes, proteins or miRNAs associated with MALAT1. The upstream regulators during the transcriptional and posttranscriptional procession and the downstream genes modulated by MALAT1 are exhibited. In addition, reciprocal interaction and other associations between MALAT1 and other genes, proteins or miRNAs are shown. MALAT1, metastasis-associated lung adenocarcinoma transcript 1; SOX17, sex-determining region-Y-box 17; SRSF1, serine/arginine-rich splicing factor 1; YAP, yes-associated protein 1; Bcl-2, B-cell lymphoma-2; miR/miRNA, microRNA; ABCA1, ATP-binding cassette transporter member 1; ROBO1, roundabout guidance receptor 1; GPC6, glupican 6; CDCP1, CUB domain-containing protein 1; LPHN2, latrophilin-2, a cell-adhesion G protein-coupled receptor and presumptive α-latrotoxin receptor; MIA2, melanoma inhibitory activity 2; LTBP3, latent transforming growth factor β-binding protein 3; PTBP2, polypyrimidine tract binding protein 2; SFPQ, splicing factor proline-glutamine rich; suz12, suz12 polycomb repressive complex 2 subunit; Ezh2, enhancer of zeste homolog 2; Bax, Bcl-2-associated X protein; Bcl-xl, B-cell lymphoma-extra-large; TDP43, TAR DNA-binding protein 43; lncRNA, long non-coding RNA; AKAP-9, A-kinase anchor protein-9.
Figure 2. Genes, proteins or miRNAs associated with MALAT1. The upstream regulators during the transcriptional and posttranscriptional procession and the downstream genes modulated by MALAT1 are exhibited. In addition, reciprocal interaction and other associations between MALAT1 and other genes, proteins or miRNAs are shown. MALAT1, metastasis-associated lung adenocarcinoma transcript 1; SOX17, sex-determining region-Y-box 17; SRSF1, serine/arginine-rich splicing factor 1; YAP, yes-associated protein 1; Bcl-2, B-cell lymphoma-2; miR/miRNA, microRNA; ABCA1, ATP-binding cassette transporter member 1; ROBO1, roundabout guidance receptor 1; GPC6, glupican 6; CDCP1, CUB domain-containing protein 1; LPHN2, latrophilin-2, a cell-adhesion G protein-coupled receptor and presumptive α-latrotoxin receptor; MIA2, melanoma inhibitory activity 2; LTBP3, latent transforming growth factor β-binding protein 3; PTBP2, polypyrimidine tract binding protein 2; SFPQ, splicing factor proline-glutamine rich; suz12, suz12 polycomb repressive complex 2 subunit; Ezh2, enhancer of zeste homolog 2; Bax, Bcl-2-associated X protein; Bcl-xl, B-cell lymphoma-extra-large; TDP43, TAR DNA-binding protein 43; lncRNA, long non-coding RNA; AKAP-9, A-kinase anchor protein-9.CC BY-NC-ND · PubMed Central

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Metadata

Authors
Zhao, M., Wang, S., Li, Q., Ji, Q., Guo, P., & Liu, X.
Affiliations
  • Department of Traditional Chinese Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, P.R. China
  • Department of Oncology, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, P.R. China
Venue
Oncology Letters
Publisher
Spandidos Publications
Published
2018-05-02
ISSN
  • 1792-1074
  • 1792-1082
DOI
10.3892/ol.2018.8613
PMC
PMC6006327
Cited by
32
References
3

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Zhao, M., Wang, S., Li, Q., Ji, Q., Guo, P., & Liu, X. (2018). MALAT1: A long non‑coding RNA highly associated with human cancers (Review). Oncology Letters. https://doi.org/10.3892/ol.2018.8613